Comparing Canada's proposed Critical Cyber Systems Protection Act with cybersecurity legal requirements in the EU.

This article examines the Canadian federal government's proposed Critical Cyber Systems Protection Act (CCSPA), compares it with existing and proposed cybersecurity legal requirements in the European Union (EU), and sets out recommendations to address shortcomings of the proposed Canadian legislation. One of the cornerstone components of Bill C­26, the CCSPA seeks to regulate critical cyber systems in federally regulated private sectors. It represents a significant overhaul of Canadian cybersecurity regulation. However, the current proposed legislation exhibits many flaws, including a commitment to, and entrenchment of, a patchwork approach to regulation that focuses on formal registration; a lack of oversight of its confidentiality provisions; a weak penalty scheme that focuses solely on compliance, not deterrence; and diluted conduct, reporting, and mitigation obligations. To repair these flaws, this article reviews the provisions of the proposed law and compares them with the EU's Directive Concerning Measures for a High Common Level of Security of Network and Information Systems Across the Union, the first EU-wide cybersecurity legislation, as well as its proposed successor, the NIS2 Directive. Where relevant, various other cybersecurity regulations in peer states are discussed. Specific recommendations are put forward.

Cell salvage in acute and chronic wounds: a potential treatment strategy. Experimental data and early clinical results.

On 9 May 2018, the authors took part in a closed panel discussion on the impact of cell salvage in acute and chronic wounds. The goal was to deliberate the possible use of plurogel micelle matrix (PMM) as a new treatment strategy for wound healing and the authors openly shared their experiences, thoughts, experimental data and early clinical results. The outcome of the panel discussion has been abridged in this paper. The cell membrane consists of a lipid bilayer, which provides a diffusion barrier separating the inside of a cell from its environment. Cell membrane injury can result in acute cellular necrosis when defects are too large and cannot be resealed. There is a potential hazard to the body when these dying cells release endogenous alarm signals referred to as 'damage (or danger) associated molecular patterns' (DAMPs), which trigger the innate immune system and modulate inflammation. Cell salvage by membrane resealing is a promising target to ensure the survival of the individual cell and prevention of further tissue degeneration by inflammatory processes. Non-ionic surfactants such as poloxamers, poloxamines and PMM have the potential to resuscitate cells by inserting themselves into damaged membranes and stabilising the unstable portions of the lipid bilayers. The amphiphilic properties of these molecules are amenable to insertion into cell wall defects and so can play a crucial, reparative role. This new approach to cell rescue or salvage has gained increasing interest as several clinical conditions have been linked to cell membrane injury via oxidative stress-mediated lipid peroxidation or thermal disruption. The repair of the cell membrane is an important step in salvaging cells from necrosis to prevent further tissue degeneration by inflammatory processes. This is applicable to acute burns and chronic wounds such as diabetic foot ulcers (DFUs), chronic venous leg ulcers (VLUs), and pressure ulcers (PUs). Experimental data shows that PMM is biocompatible and able to insert itself into damaged membranes, salvaging their barrier function and aiding cell survival. Moreover, the six case studies presented in this paper reveal the potential of this treatment strategy.

A Need to Know Basis? Canadian Federalism and the Disclosure of Egg and Sperm Donor Identities.

In Canada, gamete donation can be known or anonymous. When a child is conceived using anonymously donated gametes, that child does not have a right to know the identity of their donor. Currently, there is no registry storing gamete donor information accessible to donor-conceived persons and no legislation or judicial precedent protecting a donor-conceived person's right to know the identity of their biological parent(s). With third party reproduction now regularly shifting the traditional outlines of family, these practices are increasing- ly attracting judicial oversight. This paper examines the consequences of the Supreme Court of Canada's Reference re Assisted Human Reproduction Act, S.C. 2004, c. 2 (AHRA), which identified donor anonymity as a matter of provincial jurisdiction. The paper argues that the Supreme Court's decision defined the future of anonymous gamete donation in Canada by strongly protecting anonymity.