ABSTRACT
This case report discusses the dislocation of a Descemet stripping endothelial keratoplasty (DSEK) lenticule in a man aged 82 years who underwent DSEK for pseudophakic bullous keratopathy.
Subject(s)
Corneal Diseases , Descemet Stripping Endothelial Keratoplasty , Humans , Corneal Diseases/surgery , Endothelium, Corneal , Anterior Chamber/surgery , Descemet Membrane/surgeryABSTRACT
Brittle cornea syndrome (BCS) is a genetic connective tissue disorder with discernible ocular features such as blue scleral and thin cornea that predominantly presents in younger children. We herein describe cases of three siblings with BCS, two of whom presented to us with open globe injuries following trivial trauma. Clinical examination of the other eye in both showed diffusely thin corneas and blue sclera. A systemic evaluation revealed sensorineural hearing loss and hyperextensible joints. The third sibling was screened and found to have features concurrent with BCS. This report highlights the challenges faced in the management of ocular injuries and consecutive complications in these patients.
Subject(s)
Eye Abnormalities , Joint Instability , Skin Abnormalities , Child , Eye Abnormalities/diagnosis , Eye Abnormalities/genetics , Humans , Joint Instability/congenital , Joint Instability/etiology , Joint Instability/genetics , Male , Siblings , Skin Abnormalities/diagnosis , Skin Abnormalities/geneticsABSTRACT
The aim of our retrospective study is to report a case series of ocular infections caused by a rare fungus, Scedosporium apiospermum, in a South Indian population. Thirteen cases of culture-positive S. apiospermum infections diagnosed between January 2011 and March 2016 were included in this study. The parameters evaluated were predisposing factors, treatment and final clinical outcome. The most common mode of presentation was keratitis (84.6%) followed by sclerokeratitis (15.3%). The predisposing factors involved were unspecified foreign body injury (30.7%), organic matter injury (15.3%), uncontrolled diabetes (7.6%), and recent manual small-incision cataract surgery (7.6%). Five cases (38.46%) had no predisposing factor. Of the 11 keratitis cases, nine (69.2%) responded well to combination medical therapy while one case (7.6%) required therapeutic keratoplasty. One case was lost to follow-up. Both cases which presented with sclerokeratitis showed no response to medico-surgical treatment progressing to panophthalmitis and evisceration.