ABSTRACT
Solitary epithelioid histiocytoma (previously called reticulohistiocytoma) is a rare benign dermal histiocytic proliferation characterized by the presence of large, eosinophilic histiocytes with 'glassy' cytoplasm. This entity assumes importance because of its close histologic resemblance to several benign as well as malignant cutaneous lesions. Involvement of the penis is extremely rare, and to our knowledge, only one case has been previously described in the literature. We report a case of solitary epithelioid histiocytoma in a 34-year-old man who presented with a nodule in the glans penis. Microscopy showed proliferation of large epithelioid histiocytes with abundant eosinophilic cytoplasm, which expressed CD68, CD163 and vimentin. This case highlights the significance of recognizing this unusual lesion and differentiating it from its histologic mimics.
Subject(s)
Histiocytosis, Non-Langerhans-Cell/pathology , Penile Diseases/pathology , Adult , Histiocytosis, Non-Langerhans-Cell/surgery , Humans , Immunohistochemistry , Male , Penile Diseases/surgeryABSTRACT
Acute appendicitis of amebic origin is considered a rare cause of acute appendicitis. We report a case of amebic appendicitis presenting with fever, severe pain in the right lower quadrant of the abdomen and rebound tenderness. Lab investigations revealed neutrophilic leukocytosis. The patient underwent appendectomy. Histopathological examination revealed numerous Entameba histolytica trophozoites in the mucosa of the appendix. Acute appendicitis of amebic origin does not appear frequently. Appendicular amebiasis can give the clinical features of acute appendicitis and should be treated accordingly.
Subject(s)
Appendicitis/diagnosis , Appendicitis/parasitology , Dysentery, Amebic/diagnosis , Dysentery, Amebic/parasitology , Entamoeba histolytica/isolation & purification , Adult , Appendectomy , Appendicitis/pathology , Appendicitis/surgery , Dysentery, Amebic/pathology , Dysentery, Amebic/surgery , Histocytochemistry , Humans , MaleABSTRACT
The paranasal sinuses are an extremely unusual location for a vascular hamartoma. As far as we know, only 1 such case has been previously reported in the English-language literature. We report 3 new cases of vascular hamartoma of the paranasal sinuses, which occurred in a 20-year-old woman and in 2 men aged 36 and 45 years. Radiologically, the lesion in the woman was confined to the sinuses, while evidence of intraorbital extension was seen in the 2 men. No intracranial extension was seen in any patient. The diagnosis was confirmed by histopathologic examination of the excised lesions. All 3 patients were alive without recurrence at 12 to 24 months of follow-up.
Subject(s)
Hamartoma/pathology , Hamartoma/surgery , Paranasal Sinus Diseases/pathology , Paranasal Sinus Diseases/surgery , Adult , Biopsy, Needle , Female , Follow-Up Studies , Hamartoma/diagnostic imaging , Humans , Immunohistochemistry , Male , Middle Aged , Paranasal Sinus Diseases/diagnostic imaging , Rare Diseases , Risk Assessment , Sampling Studies , Tomography, X-Ray Computed , Treatment Outcome , Young AdultABSTRACT
Proliferating trichilemmal tumor (PTT) is an uncommon, usually benign lesion that usually arises on the scalp of elderly women. The lesion bears close morphologic resemblance to squamous cell carcinoma at the microscopic level, making correct histologic diagnosis extremely important. We present a case of PTT occurring on the chest wall of a 75-years-old man to highlight the significance of recognizing this unusual tumor at an uncommon location and discuss points of differentiation from squamous cell carcinoma.
