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1.
Sensors (Basel) ; 23(24)2023 Dec 13.
Article in English | MEDLINE | ID: mdl-38139637

ABSTRACT

Microelectromechanical systems (MEMS)-based filter with microchannels enables the removal of various microorganisms, including viruses and bacteria, from fluids. Membranes with porous channels can be used as filtration interfaces in MEMS hemofilters or mini-dialyzers. The main problems associated with the filtration process are optimization of membrane geometry and fouling. A nanoporous aluminum oxide membrane was fabricated using an optimized two-step anodization process. Computational strength modeling and analysis of the membrane with specified parameters were performed using the ANSYS structural module. A fuzzy simulation was performed for the numerical analysis of flux through the membrane. The membrane was then incorporated with the prototype for successive filtration. The fluid flux and permeation analysis of the filtration process have been studied. Scanning electron microscope (SEM) micrographs of membranes have been obtained before and after the filtration cycles. The SEM results indicate membrane fouling after multiple cycles, and thus the flux is affected. This type of fabricated membrane and setup are suitable for the separation and purification of various fluids. However, after several filtration cycles, the membrane was degraded. It requires a prolonged chemical cleaning. High-density water has been used for filtration purposes, so this MEMS-based filter can also be used as a mini-dialyzer and hemofilter in various applications for filtration. Such a demonstration also opens up a new strategy for maximizing filtration efficiency and reducing energy costs for the filtration process by using a layered membrane setup.

2.
Sensors (Basel) ; 20(13)2020 Jun 30.
Article in English | MEDLINE | ID: mdl-32630055

ABSTRACT

The demand of devices for safe mobility of blind people is increasing with advancement in wireless communication. Artificial intelligent devices with multiple input and output methods are used for reliable data estimation based on maximum probability. A model of a smart home for safe and robust mobility of blind people has been proposed. Fuzzy logic has been used for simulation. Outputs from the internet of things (IoT) devices comprising sensors and bluetooth are taken as input of the fuzzy controller. Rules have been developed based on the conditions and requirements of the blind person to generate decisions as output. These outputs are communicated through IoT devices to assist the blind person or user for safe movement. The proposed system provides the user with easy navigation and obstacle avoidance.


Subject(s)
Environment Design , Fuzzy Logic , Housing , Internet of Things , Visually Impaired Persons , Artificial Intelligence , Computer Simulation , Humans
3.
R Soc Open Sci ; 6(5): 182135, 2019 May.
Article in English | MEDLINE | ID: mdl-31218038

ABSTRACT

Magnetic cores loaded with metallic nanoparticles can be promising nano-carriers for successful drug delivery at infectious sites. We report fabrication, characteristic analysis and in vitro antibacterial performance of nanocomposites comprising cobalt cores (Co-cores) functionalized with a varied concentration of silver nanoparticles (AgNPs). A two-step polyol process synchronized with the transmetalation reduction method was used. Co-cores were synthesized with cobalt acetate, and decoration of AgNPs was carried out with silver acetate. The density of AgNPs was varied by changing the amount of silver content as 0.01, 0.1 and 0.2 g in the synthesis solution. Both AgNPs and Co-cores were spherical having a size range of 30-80 nm and 200 nm to more than 1 µm, respectively, as determined by scanning electron microscopy. The metallic nature and face-centred cubic crystalline phase of prepared nanocomposites were confirmed by X-ray diffraction. Biocompatibility analysis confirmed high cell viability of MCF7 at low concentrations of tested particles. The antibacterial performance of nanocomposites (Co@AgNPs) against Escherichia coli and Bacillus subtilis was found to be AgNPs density-dependent, and nanocomposites with the highest AgNPs density exhibited the maximum bactericidal efficacy. We therefore propose that Co@AgNPs as effective drug containers for various biomedical applications.

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