ABSTRACT
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Subject(s)
Humans , Male , Adult , Sertoli Cell Tumor/surgery , Testicular Neoplasms/surgery , Diagnosis, DifferentialABSTRACT
Objetivo: Comunicación de dos casos clínicos con diagnóstico de linfoma testicular primario y revisión de la literatura existente sobre esta patología. Métodos/ Resultados: Descripción de dos casos de linfoma testicular primario en dos varones de 69 y 61 años. En ambos casos su motivo de consulta fue un aumento de volumen testicular derecho. Tras practicar una orquiectomía inguinal se diagnóstico, en el primer caso, un linfoma difuso tipo T de células grandes y medianas, estadio I (E)-A, que tras seguir tratamiento con quimioterapia (R-CHOP) se mantiene en remisión a los tres años. En el segundo caso, el diagnóstico fue de linfoma difuso de células grandes tipo B, que tras recibir distintas pautas de quimioterapia, falleció a los 14 meses del diagnóstico. Conclusiones: El linfoma testicular es una entidad muy poco frecuente, a pesar de ser considerado el tumor testicular más común en mayores de 60 años. En su mayoría se trata de linfomas no Hodgkin difusos de grado intermedio alto de malignidad e inmunofenotipo B, considerando como excepcionales los de tipo T. Su pronóstico es pobre debido a su gran tendencia a la propagación sistémica. Su tratamiento se basa en orquiectomía, quimioterapia y radioterapia, si bien no existe una pauta estandarizada del mismo (AU)
Objective: We report two cases of primary testicular lymphoma and performed a bibliography review about this pathology. Methods/Results: We describe two cases of primary testicular lymphoma in two male patients 69 and 61 yr. old respectively. In both cases, reason for consultation was increase of the right testicular size. After inguinal orchyectomy the diagnosis for the first case was large and medium T cell diffuse lymphoma, stage I (E)-A; three years after chemotherapy (R-CHOP) the patient is in complete remission. In the second case, the diagnosis was diffuse large B-cell lymphoma, and after receiving various chemotherapy regimens died 14 months after diagnosis. Conclusions: Testicular lymphoma is a very rare entity, despite being considered the most common testicular tumor in patients over the age of 60 years. Most of them are non-Hodgkin diffuse, intermediate or high grade of malignancy , B-cell immunophenotype, being T-cell exceptional. Prognosis is poor due to their high tendency to systemic dissemination. The treatment is based on orchiectomy, chemotherapy and radiotherapy, although there is not a standardized regimen (AU)
Subject(s)
Humans , Male , Middle Aged , Testicular Neoplasms/diagnosis , Testicular Neoplasms/therapy , Lymphoma/complications , Orchiectomy/methods , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/drug therapy , Germinoma/complications , Lymphoma, Non-Hodgkin/complications , Leydig Cells/pathology , Leydig Cells , Testicular Diseases/pathologyABSTRACT
Pure primary squamous cell carcinoma (SCC) is an extremely rare type of breast tumor. We report one of such cases in a 32-year-old woman, diagnosed by fine-needle aspiration cytology (FNAC). Aspiration smears were characterized by squamous cells, both isolated and in aggregates, at various stages of maturation. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. Pure primary SCC of the breast has a distinctive cytomorphologic appearance, and diagnosis of this tumor by FNAC is possible. For its diagnosis, the exclusion of SCC of local cutaneous structures and metastasis of distant squamous carcinoma are mandatory.
Subject(s)
Biopsy, Fine-Needle , Breast Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Adult , Breast Neoplasms/therapy , Carcinoma, Squamous Cell/therapy , Chemotherapy, Adjuvant , Female , Humans , Radiotherapy, AdjuvantABSTRACT
We report a case of retroperitoneal leiomyosarcoma recurrence. This entity is rare, < 0.2% of all tumours in humans and 25-30% of retroperitoneal sarcomas. The diagnosis is usually delayed in relationship with scarce clinical signs which favorite the development of great tumour volume before diagnosis. The treatment is surgical, with wide margins excision. Radiotherapy and chemotherapy are not adequates for treatment of this pathological entity.
Subject(s)
Leiomyosarcoma/diagnosis , Retroperitoneal Neoplasms/diagnosis , Female , Humans , Middle AgedABSTRACT
Se presenta un caso de recidiva tumoral de un leiomiosarcoma retroperitoneal. Son tumores infrecuentes, representando < 0,2 por ciento de todas las tumoraciones del organismo, y de un 25-30 por ciento de los sarcomas retroperitoneales. Suelen diagnosticarse tardíamente debido a su vaga sintomatología, alcanzando grandes volúmenes tumorales. El tratamiento es la completa escisión quirúrgica con amplios márgenes, no habiendo demostrado utilidad otras terapias como la radioterapia o la quimioterapia (AU)
Subject(s)
Middle Aged , Female , Humans , Leiomyosarcoma , Retroperitoneal NeoplasmsABSTRACT
We present a case of pure prostatic leiomyoma, benign and rare entity, diagnosed in a patient with prostatism. We review the published papers about this disease and the different subjects about etiology, clinic, histopathology, diagnosis and treatment.
Subject(s)
Leiomyoma/pathology , Prostatic Neoplasms/pathology , Aged , Humans , MaleABSTRACT
Se presenta un nuevo caso de leiomioma de próstata puro, tumor benigno de presentación infrecuente, diagnosticado en un varón con prostatismo. Se realiza revisión de la literatura existente y se comentan los aspectos etipatogénicos, clínicos, anatomopatológicos, diagnósticos y terapéuticos (AU)
Subject(s)
Aged , Male , Humans , Leiomyoma , Prostatic NeoplasmsABSTRACT
The hyperthyroidism is associated to different clinical situations with a relative frequency on the daily practice. Anyway, there have been discovered and published some clinical cases of thyroid cancer with insufficient symptoms, associated with a typical clinical hyperthyroidism and that have been related with Graves Basedow Disease. We expose here two different kinds of non typical thyroid cancer as a contribution to medical literature. In these cases, thanks to a careful exploration, further tests and, above all, fine needle aspiration puncture, hidden cancer was discovered. Cancer was not expected because of clinical symptoms. The definitive treatment was marked by fine needle aspiration puncture.
Subject(s)
Adenoma/diagnosis , Carcinoma, Papillary/diagnosis , Thyroid Neoplasms/diagnosis , Adenoma/surgery , Adult , Biopsy, Needle , Carcinoma, Papillary/surgery , Chronic Disease , Female , Graves Disease/diagnosis , Graves Disease/surgery , Humans , Thyroid Gland/pathology , Thyroid Neoplasms/surgery , ThyroidectomyABSTRACT
El hipertiroidismo va asociado a distintas entidades clínicas de relativa frecuencia en la practica diaria. No obstante no debemos olvidar que existen casos de cancer de tiroides de presentación larvada asociados a una clínica hipertiroidea típica que han sido publicados, y que se han relacionado principalmente con la enfermedad de Graves Basedow. Presentamos aquí, dos casos de cancer de tiroides de presentación atípica, para añadir a la literatura. En estos casos la exploración cuidadosa, las pruebas complementarias y sobre todo la PAAF fueron las que indicaron la existencia de un carcinoma oculto, que dada la presentación del cuadro clínico no se sospechaba inicialmente. Fue la PAAF la que permitió aplicar el tratamiento definitivo (AU)
Subject(s)
Adult , Female , Humans , Adenoma , Biopsy, Needle , Carcinoma, Papillary , Chronic Disease , Graves Disease/surgery , Graves Disease/diagnosis , Thyroid Gland/pathology , Thyroidectomy , Thyroid Neoplasms , Adenoma/surgery , Adenoma/diagnosis , Carcinoma, Papillary/surgery , Carcinoma, Papillary/diagnosis , Graves Disease , Thyroid Neoplasms/surgery , Thyroid Neoplasms/diagnosisABSTRACT
Presentation of one case of inverted papilloma of the renal pelvis, an uncommon entity with very few cases described in the international literature. The pathoanatomic presentation is that of a benign tumour, which would provide an option for conservative therapy through segmentary resection and termino-terminal anastomosis. Due to its low frequency, pre-operative diagnosis of this tumour is difficult, although the number of diagnosis could be increased with the use of endourologic techniques. In spite of the benign nature, it can be multifocal and relapsing. A close follow-up monitoring is recommended.
Subject(s)
Papilloma, Inverted/pathology , Ureteral Neoplasms/pathology , Humans , Male , Middle AgedSubject(s)
Amyloidosis/pathology , Lung Diseases/pathology , Biopsy, Needle , Humans , Male , Middle AgedABSTRACT
The cytologic findings in fine needle aspiration smears and cell blocks from a malignant retroperitoneal paraganglioma with subsequent histologic confirmation are described. The aspirate contained clusters of cells with ill-defined borders, often varied in size, round or oval nuclei and marked anisokaryosis. An unusual feature was the presence of prominent intranuclear vacuoles in some cells. The histologic and ultrastructural findings, as well as the results of histochemical and immunodiagnostic staining, are also presented.
Subject(s)
Paraganglioma/pathology , Retroperitoneal Neoplasms/pathology , Adenocarcinoma/pathology , Adenoma, Islet Cell/pathology , Biopsy, Needle , Carcinoma, Hepatocellular/pathology , Cell Nucleus/pathology , Chromogranins/analysis , Diagnosis, Differential , Humans , Immunohistochemistry , Liver Neoplasms/pathology , Male , Middle Aged , Paraganglioma/ultrastructure , Retroperitoneal Neoplasms/ultrastructureABSTRACT
We present a case of rhinoscleroma that were studied in a spanish patient. The location was nasal and extranasal, appearing in the larynx. The diagnosis was established by the morphological picture. A review is given of the geographical distribution of this disease and the principal diagnostic procedures are outlined with special emphasis ou the most reliable staining methods (PAS, Gram), immunofluorescence, immunoperoxydase reactions and electron microscopic study are discussed.
