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Growth Factors ; 40(5-6): 163-174, 2022 11.
Article in English | MEDLINE | ID: mdl-36026559

ABSTRACT

Platelet-rich blood derivatives are being nowadays increasingly used in the treatment of tendon-related pathologies as a rich source of growth factors. We sought to ascertain if local application of platelet lysate (PL) to augment rotator cuff repair ameliorates patient outcomes compared to ketorolac tromethamine treated group. A total of forty patients, with clinical diagnosis of Rotator Cuff Tendinopathy were randomized to receive sub acromial injections of PL every week for a total of 3 injections and two injection of ketorolac tromethamine once every two weeks. Subjective assessments included VAS, SPADI and shoulder range of motion were assessed at baseline and at 1 and 6 months after injection. Taking both control and PL groups, it was vividly seen that the outcomes were identical at the initial state, as well as the short-term one; whereas, when considering the 6-month period, there is a seemingly remarkable superiority in PL group in all parameters.


Subject(s)
Platelet-Rich Plasma , Rotator Cuff Injuries , Tendinopathy , Humans , Rotator Cuff , Ketorolac Tromethamine/therapeutic use , Rotator Cuff Injuries/drug therapy , Tendinopathy/drug therapy , Tendons , Treatment Outcome
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