ABSTRACT
This study sought to analyze an explanatory model on the relationship among sociodemographic factors, health-promoting lifestyle behaviors and psychological distress (depression, anxiety and stress) in college students. This is an observational, analytical and cross-sectional study conducted on a national sample of 4203 students who entered a macro university in Honduras in 2021, 2022 and 2023. We used a sociodemographic survey, the Health-Promoting Lifestyle Profile (HPLP-II) and the Depression, Anxiety and Stress Scales (DASS-21). Univariate analysis and a multivariate structural equation model were conducted. The average HPLP-II score was 117.45 (±â 23.41), and the average DASS-21 score was 20.06 (±â 14.16). The multivariate model showed a good data fit (comparative fit indexâ =â 0.951; Tucker-Lewis indexâ =â 0.957; root mean square error of approximationâ =â 0.067 [90% CIâ =â 0.067-0.068]). Results indicate that being a woman (ßâ =â 0.11; pâ <â 0.001) and being enrolled in biological and health sciences (ßâ =â 0.09; pâ <â 0.001) significantly predict HPLP-II scores. Furthermore, being a woman (ßâ =â 0.17; pâ <â 0.001), age (ßâ =â 0.10; pâ <â 0.001) and having pre-existing medical conditions (ßâ =â 0.16; pâ <â 0.001) significantly explain part of the variance of DASS-21. A significant reverse relationship between health-promoting behavior and psychological distress was shown (râ =â -0.36; pâ <â 0.001). This study identifies protective and risky sociodemographic factors linked to health-promoting lifestyle behaviors and psychological distress. Our findings have implications for developing comprehensive intervention policies and strategies to promote health in higher education settings.