Cancer mortality in workers at risk of occupational exposure to ionizing radiation in a company in the nuclear sector headquarters in São Paulo.

OBJECTIVE: To compare cancer mortality among workers exposed to gamma and X radiation and the general population of the city of São Paulo, as well as that of the subgroup monitored with those not monitored for gamma and X radiation in a work unit with ionizing radiation based in the city of São Paulo. METHODS: Between 2016 and 2021, a retrospective open cohort study was carried out with workers who were employed from 08/31/1956 to 12/31/2016 based on data collected at the company and in official institutions. Standardized mortality ratios (SMR) were calculated by sex, age and calendar period of cancers grouped according to type, risk factor and organ system in two analyses: in the external analysis, the mortality of the study population was compared with that of the general population of the city of São Paulo; In the internal analysis, the mortality of the monitored subgroup was compared with that of the subgroup not monitored for gamma and X radiation. RESULTS: The external mortality analysis showed SMR=0.224 (95%CI 0.208-0.240) and the healthy worker effect, while the internal mortality analysis showed SMR=0.685 (95%CI 0.618-0.758). CONCLUSION: This study showed lower cancer mortality among exposed workers when compared to mortality in the general population and the healthy worker effect. Among workers monitored for gamma and X radiation, cancer mortality was lower when compared to those not monitored.

Cancer mortality in workers at risk of occupational exposure to ionizing radiation in a company in the nuclear sector headquarters in São Paulo / Mortalidade por câncer em trabalhadores com risco de exposição ocupacional à radiação ionizante em empresa do setor nuclear sediada em São Paulo

ABSTRACT Objective: To compare cancer mortality among workers exposed to gamma and X radiation and the general population of the city of São Paulo, as well as that of the subgroup monitored with those not monitored for gamma and X radiation in a work unit with ionizing radiation based in the city of São Paulo. Methods: Between 2016 and 2021, a retrospective open cohort study was carried out with workers who were employed from 08/31/1956 to 12/31/2016 based on data collected at the company and in official institutions. Standardized mortality ratios (SMR) were calculated by sex, age and calendar period of cancers grouped according to type, risk factor and organ system in two analyses: in the external analysis, the mortality of the study population was compared with that of the general population of the city of São Paulo; In the internal analysis, the mortality of the monitored subgroup was compared with that of the subgroup not monitored for gamma and X radiation. Results: The external mortality analysis showed SMR=0.224 (95%CI 0.208-0.240) and the healthy worker effect, while the internal mortality analysis showed SMR=0.685 (95%CI 0.618-0.758). Conclusion: This study showed lower cancer mortality among exposed workers when compared to mortality in the general population and the healthy worker effect. Among workers monitored for gamma and X radiation, cancer mortality was lower when compared to those not monitored.

RESUMO Objetivo: Comparar a mortalidade por câncer entre trabalhadores expostos à radiação gama e X e a população geral do município de São Paulo, bem como a do subgrupo monitorado com o não monitorado para radiação gama e X em uma unidade de trabalho sediada no município de São Paulo. Métodos: Entre 2016 e 2021 foi realizado estudo de coorte aberta retrospectiva com trabalhadores que tiveram vínculo empregatício desde 31/08/1956 até 31/12/2016 a partir de dados coletados na empresa e em instituições oficiais. Foram calculadas as razões de mortalidade padronizadas (RMP) por sexo, idade e período calendário de cânceres agrupados segundo o tipo, o fator de risco e o sistema orgânico em duas análises: na análise externa, comparou-se a mortalidade da população de estudo com a da população geral do município de São Paulo; já na análise interna, comparou-se a mortalidade do subgrupo monitorado com a do subgrupo não monitorado para radiação gama e X. Resultados: A análise externa de mortalidade mostrou RMP=0,224 (IC95% 0,208-0,240) e o efeito do trabalhador sadio, enquanto a análise interna de mortalidade mostrou RMP = 0,685 (IC95% 0,618-0,758). Conclusão: Este estudo mostrou menor mortalidade por câncer entre os trabalhadores expostos quando comparada com a mortalidade da população geral e o efeito do trabalhador sadio. Entre os trabalhadores monitorados para radiação gama e X, a mortalidade por câncer foi menor quando comparada com a dos não monitorados.

Psychometric Properties of an Instrument for Assessing University Administrators' Knowledge on Gender-Based Violence.

OBJECTIVE: To evaluate the factorial structure of the instrument measuring university administrators' knowledge of gender-based violence. METHODS: This cross-sectional methodological study was conducted from August to November 2020 with 101 university administrators. Data on demographic and functional characteristics were collected, and the "QUEST VBG UNIV" instrument was applied. Descriptive analysis was performed, the structure of the questionnaire was assessed using exploratory factor analysis (EFA), and the stability of the factors was verified through ORION and FDI tests. RESULTS: Of the original 38 items across the 4 sections of the questionnaire, 19 were retained within 2 factors, with appropriate factor loadings. Factor 1 had an explained variance of 15.69%, and Factor 2 had an explained variance of 9.10%. The reliability was deemed satisfactory (ORION > 0.900, FDI > 0.900). CONCLUSIONS: The questionnaire presented a valid and reliable factorial structure for measuring knowledge about gender-based violence, thereby representing a suitable option for situational assessments in universities.

Comprometimento da Capacidade para o Trabalho e efeitos neuropsicológicos entre trabalhadores com Covid-19 prévia / Impairment of Work Ability and neuropsychological effects among workers who have had COVID-19

RESUMO A Covid-19 é uma doença multissistêmica e consequências funcionais e tardias estão em estudo. Sequelas psicológicas e neurocognitivas podem comprometer a Capacidade para o Trabalho (CT) dos trabalhadores. Objetivou-se investigar a CT de pessoas previamente infectadas pelo Sars-CoV-2, correlacionando-a com avaliação da sonolência, ansiedade, depressão e fadiga. Estudo transversal, com trabalhadores diagnosticados com Covid-19 e em acompanhamento no Serviço de Neurologia da Universidade Estadual de Campinas (Unicamp). Aplicou-se o instrumento Índice de Capacidade para o Trabalho (ICT), um formulário com dados sociodemográficos e ocupacionais, bem como escalas de sonolência, ansiedade, depressão e fadiga. Dos 119 trabalhadores que participaram do estudo, mais da metade apresentaram comprometimento da CT (52,9%). Distúrbio emocional foi o agravo relatado mais frequente (31,9%). A regressão logística múltipla mostrou que a interação entre ansiedade e sonolência esteve associada ao comprometimento da CT (OR=4,50 com p=0,002). Ansiedade e sonolência foram alterações tardias da Covid-19 e associadas ao comprometimento da CT dos trabalhadores avaliados. Este estudo demonstra a necessidade de que todos os trabalhadores com teste positivo por Covid-19 tenham sua CT avaliada por ocasião do retorno ao trabalho. Ações de promoção à saúde, reabilitação funcional e adaptação do trabalho de acordo com as sequelas apresentadas pelos trabalhadores.

ABSTRACT COVID-19 is a multisystemic disease, with functional and late consequences still under study. Psychological and neurocognitive sequelae impact workers' quality of life and may compromise the Work Ability (WA). The objective was to investigate the WA of people infected with SARS-CoV-2, correlating it with the assessment of sleepiness, anxiety, depression and fatigue. Cross-sectional study, involving workers diagnosed with COVID-19 under follow-up at the Department of Neurology of Universidade Estadual de Campinas (UNICAMP). Application of the Work Ability Index (WAI) analyzed with sociodemographic and occupational variables, as well the sleepiness, anxiety, depression and fatigue scales. Multiple logistic regression analysis was performed. 119 workers participated in the study and, among them, more than half had WA impairment (52.9%). Emotional disorders were the most frequent reported problem (31.9%). Multiple logistic regression showed that the interaction between anxiety and sleepiness was associated with WA impairment (OR=4.50, p=0.002). Anxiety and sleepiness were associated with previous COVID-19 and they were associated with WA impairment among workers. This study shows the WA evaluation should be provided for all workers with a previous history of COVID-19, when they return to work. This assessment can guide health promotion actions, functional rehabilitation and work adaptation to the sequelae presented by workers, singularly.

Return to work after sick leave due to musculoskeletal disorder or injury: a longitudinal study conducted in Brazil.

BACKGROUND: Musculoskeletal disorders and injuries (MSDI) are conditions that affect the locomotor system characterized by pain and impairment of functionality. They are the leading cause of years lived with disability. The aim of this study was to analyze the factors that influence the return to work (RTW) among workers on sick leave due to MSDI.   METHODS: A longitudinal study was conducted in the city of São Paulo, Brazil, between 2020-2022. The participants were 216 workers who required social security compensation due to MSDI. They filled out online questionnaires about their sociodemographic characteristics, health risk behaviors, work characteristics and health conditions. They were followed for 365 days after their first day of sick leave. A Cox regression was performed to identify the factors that influenced their first RTW. RESULTS: Most participants were male (53.0%), mean age was 39.5 years (SD 10.6), 70.4% returned to work within the one-year follow-up period. The mean duration of sick leave was 192.6 days. Factors associated with a lower RTW were age 40 years and older (HR 0.54; 95%CI 0.39-0.76) and the interaction between perceptions of the need for improvement in the physical and psychological domains of quality of life (HR 0.67; 95%CI 0.48-0.94). CONCLUSIONS: Occupational healthcare professionals should pay greater attention to patients who are aging and those with perceived worse physical and psychological conditions, in order to facilitate the reintegration process and promote sustained RTW after sick leave due to musculoskeletal disorder or injury.

Quality of life in adult patients using dialyzable leukocyte extract for allergic rhinitis.

Allergic rhinitis (AR) has considerable impact on the general health of individuals. Therefore, treatment trials should include an evaluation of quality of life. We aimed to determine changes in the quality of life of moderate/severe AR patients treated with standard treatment in addition to dialyzable leukocyte extract (DLE), a peptide-based immunomodulator. In a prospective, non-controlled trial, DLE was added to the standard treatment regimen for patients with moderate/severe AR. DLE was administered orally at 2 mg per day for 5 days, followed by 4 mg per week for 5 weeks, and then 2 mg per week for 5 weeks. The primary endpoints were overall improved Standardized Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) scores, domain scores, and individual item scores of 0.5 points or higher. Statistical significance was defined as P < .05. Thirty patients (50% female) aged 14 to 60 years old (33.4 ± 11.9) were enrolled in this study. The mean overall basal quality of life score was 3.41 ± 1.22. After 11 weeks, the mean RQLQ score was 1.74 ± 1.09 ( P < .0001; 95% confidence interval [CI], 1.05-2.33), and all the domain scores improved (daily activities P < .001, 95% CI 0.91-2.15, sleep P < .001, 95% CI 0.9-2.26, non-hay fever symptoms P = .001, 95% CI 0.51-1.82, practical problems P < .001, 95% CI 1.55-2.85, nasal symptoms P < .001, 95% CI 1.36-2.67, ocular symptoms P < .001, 95% CI 1.05-2.17, emotional P < .001, 95% CI 1.23-2.55). Each of the 28 individual item scores on the RQLQ showed clinical (minimal important difference [MID] ≥ 0.5) and statistical ( P < .05) improvements. DLE might be a beneficial adjuvant treatment for AR. Our results provide preliminary data for future research. Clinical trials registration ID: NCT02506998.

Overweight and Obesity in Brazilian Immigrants in Massachusetts, USA: A Time Series Analysis (2009-2020).

INTRODUCTION: Obesity is considered a growing public health problem by the Brazilian Ministry of Health and a global epidemic by the World Health Organization (WHO). In 2020, the Centers for Disease Control and Prevention (CDC) estimated the prevalence of adult obesity at 31.9% in the USA. The USA is one of the main destinations for Brazilian immigrants in search of better living conditions, and Massachusetts is one of the states with the highest presence of Brazilians. Changes in lifestyle and eating habits are often associated with increases in overweight and obesity in immigrants in the USA, especially Hispanics, an official classification that does not, however, include Brazilians. The aim of this study was to describe the temporal trend of overweight and obesity in Brazilian immigrants assisted by the Cambridge Health Alliance (CHA) healthcare network in Massachusetts. METHODS: This was an ecological time series study of 128,206 records of Brazilians aged between 18 and 60 years based on hospital data from 2009 to 2020. RESULTS: Mean age was 38.9 (SD = 10.6), and 61% of the sample were women. The prevalence of overweight and obesity was 38.4% and 25.4%, respectively. Obesity exhibited an increasing trend, while eutrophy and overweight decreased during the study period. CONCLUSION: As little is known about the health of Brazilian immigrants in the USA, this study contributes to the literature on the subject. The observed increasing trends agree with the worldwide increase in obesity and indicate the need for future research exploring individual factors associated with immigrant acculturation.

Psychometric Properties of an Instrument for Assessing University Administrators' Knowledge on Gender-Based Violence / Propiedades Psicométricas de un Instrumento para Evaluar el Conocimiento de los Administradores Universitarios sobre la Violencia de Género / Propriedades psicométricas de um instrumento de avaliação do conhecimento de gestores sobre violência de gênero na universidade

ABSTRACT Objective: To evaluate the factorial structure of the instrument measuring university administrators' knowledge of gender-based violence. Methods: This cross-sectional methodological study was conducted from August to November 2020 with 101 university administrators. Data on demographic and functional characteristics were collected, and the "QUEST VBG UNIV" instrument was applied. Descriptive analysis was performed, the structure of the questionnaire was assessed using exploratory factor analysis (EFA), and the stability of the factors was verified through ORION and FDI tests. Results: Of the original 38 items across the 4 sections of the questionnaire, 19 were retained within 2 factors, with appropriate factor loadings. Factor 1 had an explained variance of 15.69%, and Factor 2 had an explained variance of 9.10%. The reliability was deemed satisfactory (ORION > 0.900, FDI > 0.900). Conclusions: The questionnaire presented a valid and reliable factorial structure for measuring knowledge about gender-based violence, thereby representing a suitable option for situational assessments in universities.

RESUMEN Objetivo: Evaluar la estructura factorial del instrumento que mide el conocimiento de los administradores universitarios sobre la violencia de género. Métodos: Estudio metodológico transversal se llevó a cabo de agosto a noviembre de 2020 con 101 administradores universitarios. Se recogieron datos sobre características demográficas y funcionales, y se aplicó el instrumento "QUEST VBG UNIV". Se realizó un análisis descriptivo, se evaluó la estructura del cuestionario utilizando análisis factorial exploratorio (AFE), y se verificó la estabilidad de los factores a través de las pruebas ORION y FDI. Resultados: De los 38 ítems originales en las 4 secciones del cuestionario, se retuvieron 19 en 2 factores, con cargas factoriales adecuadas. El Factor 1 tuvo una varianza explicada del 15.69%, y el Factor 2 una varianza explicada del 9.10%. Se consideró que la fiabilidad era satisfactoria (ORION > 0.900, FDI > 0.900). Conclusiones: El cuestionario es una herramienta válida y confiable para medir el conocimiento sobre la violencia de género en las universidades.

RESUMO Objetivo: Avaliar a estrutura fatorial do instrumento de medição do conhecimento de gestores sobre violência de gênero na universidade. Métodos: Estudo transversal de caráter metodológico, realizado no período de agosto a novembro de 2020 com 101 gestores universitários. Foram coletados dados sobre características demográficas e funcionais, e o instrumento "QUEST VBG UNIV" foi aplicado. Realizou-se análise descritiva, avaliação da estrutura do questionário usando análise fatorial exploratória (AFE), e verificação da estabilidade dos fatores pelos testes ORION e FDI. Resultados: Dos 38 itens originais das 4 seções do questionário, 19 foram retidos em 2 fatores, com cargas fatoriais adequadas. O Fator 1 teve variância explicada de 15,69%, e o Fator 2 de 9,10%. A confiabilidade foi considerada satisfatória (ORION > 0,900, FDI > 0,900). Conclusões: O questionário apresentou estrutura fatorial válida e confiável para mensurar o conhecimento sobre violência de gênero, representando uma opção adequada para avaliações situacionais em universidades.

Factors associated with visual function among computer-based administrative workers: a Brazilian cross-sectional study.

Introduction: Several studies have shown that eye and vision problems are among the most significant issues reported by individuals who use computers at work. Objectives: To investigate individual and occupational environmental factors associated with visual function among workers who perform computer-based administrative tasks. Methods: This is a cross-sectional study conducted in 2014-2015 with 303 workers of a public hospital in the city of São Paulo, Brazil. The participants answered a structured questionnaire, including the 25-Item National Eye Institute Visual Function Questionnaire. Statistical analyses used descriptive analysis, tests of association and multiple linear regression analysis. Results: Most participants were female (61.1%); the mean age was 46.0 (standard deviation [SD]) ± 12.5, and approximately 91.7% of them reported wearing corrective lenses. Regarding visual function, the mean score at the 25-Item National Eye Institute Visual Function Questionnaire was 78.0, SD ±7.1. A regression analysis showed that visual function declined with age (ß -0.218; 95%CI -0.276--0.16l) and effort at work (ß -0.656; 95%CI -0.928--0.383). Conclusions: The mean quality of visual health in the studied group was good. The younger the age and the lower the effort at work, the better the visual function. Our results point to the relevance of establishing periodical and preventive health actions, including eye health assessments.

Introdução: Vários estudos mostraram que os problemas oculares e visuais são distúrbios importantes relatados por usuários de computador. Objetivos: Investigar os fatores ambientais individuais e ocupacionais associados à função visual em trabalhadores administrativos usuários de computador. Métodos: Estudo transversal realizado em 2014-2015, com 303 trabalhadores de um hospital público da cidade de São Paulo, Brasil. Os participantes responderam a um questionário estruturado, incluindo o Questionário de Função Visual do National Eye Institute de 25 Itens. A análise estatística utilizou variáveis descritivas e qualitativas e uma análise de regressão linear múltipla. Resultados: A maioria dos participantes era do sexo feminino (61,1%); a média de idade era de 46,0 (desvio-padrão) ± 12,5, aproximadamente 91,7% deles relataram o uso de lentes corretivas. O escore médio do Questionário de Função Visual do National Eye Institute de 25 Itens foi de 78,0 desvios padrão ± 7,1. A análise de regressão mostrou que a função visual diminuiu com o aumento da idade (ß −0,218; IC95% −0,276--0,161) e esforços no trabalho (ß −0,656; IC95% −0,928--0,383). Conclusões: A qualidade média da saúde visual era boa no grupo. A função visual era melhor entre os mais jovens e com percepção de menor esforço no trabalho. Os resultados apontam para a relevância de manter ações periódicas, como a avaliação da saúde ocular.

Factors associated with work ability and intention to leave nursing profession: a nested case-control study.

This study aims to identify factors associated with impaired work ability and intention to leave the nursing profession. This is a case-control nested within a cross-sectional study. Samples were randomly selected for work ability (475 controls and 158 cases) and intention to leave profession (454 controls and 151 cases). Data on demographic, lifestyle, occupational features, work environment, work ability and intention to leave profession were collected. Multiple logistic regression analysis was performed. Factors associated with work ability impairment were: risk for moderate (OR=1.28) and high (OR=2.26) job strain, effort-reward imbalance (OR=2.82), high overcommitment (OR=1.77), situations that may contribute to musculoskeletal pain/injury with moderate (OR=1.82) or high (OR=2.58) exposures, degree level (OR=2.13) or elementary/high school level (OR=1.67), and low physical activity (OR=1.74). Age of 31-40 years (OR=0.26) and ≥41 years (OR=0.27) were protective factors. Factors associated with intention to leave profession were: high risk for job strain (OR=1.81), effort-reward imbalance (OR=3.25), situations that may contribute to musculoskeletal pain/injury with high exposure (OR=1.54), and insomnia symptoms (OR=2.72). Age >40 years was a protective factor (OR=0.50). Individual characteristics and occupational conditions were associated with work ability impairment and intention to leave profession. Measures to improve working conditions and individual resources were recommended.

Fatores associados ao consumo abusivo de álcool em profissionais de enfermagem no estado de São Paulo, Brasil / Factors associated with alcohol abuse in nursing professionals in São Paulo State, Brazil

Resumo Objetivo: identificar fatores associados ao consumo abusivo de álcool entre profissionais de Enfermagem no estado de São Paulo. Métodos: trata-se de um estudo caso-controle aninhado a um transversal. Foram coletados dados sobre características demográficas, do estilo de vida, capacidade para o trabalho, aspectos ocupacionais, do ambiente de trabalho físico e psicossocial e de consumo abusivo de álcool (questionário CAGE). Foi realizada análise de regressão logística múltipla. Resultados: o estudo envolveu 119 casos e 356 controles. Após ajuste por idade, o consumo abusivo de álcool foi associado ao sexo masculino (OR: 3,39; IC95%:1,96;5,85), tabagismo atual ou pregresso (OR: 2,11; IC95%: 1,32;3,38) e à qualidade do sono ruim (OR: 1,91; IC95%:1,12;3,25); e negativamente associado a carga horária de trabalho semanal ≥50 horas (OR: 0,54; IC95%:0,32;0,92) e renda familiar mensal de ≥6,1 salários-mínimos (OR: 0,37; IC95%: 0,20;0,67). Conclusões: jornada de trabalho e características individuais estiveram associadas ao consumo abusivo de álcool. Programas de prevenção e tratamento do consumo abusivo de álcool em profissionais da Enfermagem deveriam ser implementados nos locais de trabalho, visando reduzir os danos causados pelo álcool para trabalhadores e pacientes.

Abstract Objective: to identify factors associated with alcohol abuse in nursing professionals in São Paulo State. Methods: this is a case-control nested in a cross-sectional study. We collected data on demographic characteristics, lifestyle, work ability, occupational features, physical and psychosocial work environment, and alcohol abuse (CAGE Questionnaire). Multiple logistic regression analyses were performed. Results: the study involved 119 participants in the case group and 356 in the control group. After age adjustment, alcohol abuse was associated with male sex (OR: 3.39; 95%CI: 1.96;5.85), current or former smoking (OR: 2.11; 95%CI: 1.32;3.38), and poor sleep quality (OR: 1.91; 95%CI: 1.12;3.25); and negatively associated with ≥50 weekly working hours (OR: 0.54;95%CI: 0.32;0.92) and a monthly family income ≥6.1 minimum wages(OR: 0.37; 95%CI: 0.20;0.67). Conclusions: working hours and individual characteristics were associated with alcohol abuse. Workplaces should implement programs to prevent and treat alcohol abuse in nursing professionals to reduce workers' and patients' alcohol-related harms.

Capacidade para o trabalho e intenção de saída da profissão na enfermagem de São Paulo / Work ability and intending to leave the nursing profession in São Paulo / Capacidad de trabajo e intención de dejar la profesión en enfermería en São Paulo

identificar o perfil de capacidade para o trabalho e intenção de saída da profissão na enfermagem. Método: um estudo transversal junto a 3051 profissionais do estado de São Paulo, com coleta de dados realizada por meio da internet avaliando características pessoais, ocupacionais, condições de trabalho, capacidade para o trabalho e ISP. Foi feita análise descritiva dos dados e associações verificadas por meio do teste qui-quadrado. Resultados: entre os profissionais, 55,4% tinham capacidade para o trabalho comprometida e 33,5% tinham intenção de saída presente. A intenção de saída aumentava na medida em que aumentava o comprometimento da capacidade para o trabalho (p<0,001). Foram identificadas condições físicas e psicossociais inadequadas de trabalho. Conclusão: o comprometimento da capacidade para o trabalho e a presença de intenção de saída da profissão a foram frequentes entre os profissionais de enfermagem, sendo que condições laborais inadequadas estão presentes no trabalho desse contingente profissional.

to identify the profile of work ability and intention to leave the nursing profession. Method: in this cross-sectional study of 3051 nurses in São Paulo state, data on personal and occupational characteristics, working conditions, work ability and intention to leave were collected through the Internet. Descriptive analysis was performed and associations were identified using the chi-square test. Results: 55.4% of the nurses' work ability was impaired and 33.5% intended to leave. Intention to leave increased as impairment of fitness for work increased (p < 0.001). Inadequate physical and psychosocial work conditions were identified. Conclusion: impaired work ability and the intention to leave the profession were frequent among professional nurses, and their work was found to suffer from inadequate labour conditions.

identificar el perfil de capacidad para el trabajo e intención de dejar la profesión en enfermería. Método: estudio transversal junto a 3051 profesionales del estado de São Paulo, con recolección de datos realizada a través de internet, evaluando características personales y ocupacionales, condiciones de trabajo, capacidad para el trabajo e intención de abandonarlo. Se realizó un análisis descriptivo de los datos y asociaciones verificadas mediante la prueba de chi-cuadrado. Resultados: Entre los profesionales, el 55,4% tenía capacidad de trabajo comprometida y el 33,5% tenía presente intención de dejarlo. La intención de abandonarlo crecía a medida que aumentaba la discapacidad para el trabajo (p<0,001). Se identificaron condiciones de trabajo físicas y psicosociales inadecuadas. Conclusión: la disminución de capacidad para el trabajo y la presencia de intención de dejar la profesión fueron frecuentes entre los profesionales de enfermería; se presentan también condiciones de trabajo inadecuadas en el trabajo de este contingente profesional.

Aging and the Future of Decent Work.

The United Nations identified decent work and economic growth as a sustainable development goal for 2030. Decent work is a term that sums up aspirations for people in their working lives. One of the factors that influences the achievement of decent work is aging. This article examines how aspects of aging and organizational factors affect work ability across the lifespan and throughout one's work career. Additionally, the critical issue of worker physical mobility was also addressed as a practical limitation to functional aging. Through our investigation, we identified gaps in the literature where research and interventions should be promoted. These include early disability studies; population dashboards of workers' health metrics; intervention and cost effectiveness in health promotion and prevention of early functional aging at work; policies for tailoring demands to individual needs and abilities; and inequities of social protection for aging workers.

Chitosan as a Coating for Biocontrol in Postharvest Products: A Bibliometric Review.

The aim of this work was to carry out a systematic literature review focused on the scientific production, trends, and characteristics of a knowledge domain of high worldwide importance, namely, the use of chitosan as a coating for postharvest disease biocontrol in fruits and vegetables, which are generated mainly by fungi and bacteria such as Aspergillus niger, Rhizopus stolonifera, and Botrytis cinerea. For this, the analysis of 875 published documents in the Scopus database was performed for the years 2011 to 2021. The information of the keywords' co-occurrence was visualized and studied using the free access VOSviewer software to show the trend of the topic in general. The study showed a research increase of the chitosan and nanoparticle chitosan coating applications to diminish the postharvest damage by microorganisms (fungi and bacteria), as well as the improvement of the shelf life and quality of the products.

Return to Work After a Disabling Mental Disorder: Predictors From a Brazilian 1-Year Longitudinal Study.

OBJECTIVE: This study aims to analyze factors that influence return to work (RTW) among workers on sickness absence due to mental disorders. METHODS: A longitudinal study conducted between 2014 and 2017 in São Paulo, Brazil. The 385 participants answered a questionnaire including sociodemographics, habits/lifestyle, job characteristics, and clinical information. Survival analysis was performed to identify factors influencing the RTW. RESULTS: Most of participants were females (74.5%), worked in jobs dealing with public (44.2%) and were depressed (52.4%). RTW occurred for 68.3% participants over 1-year follow-up. Mean duration of absence was 163.83 days. The risk profile for remaining absent was heavy smokers, be abstainer, obese, deal with the public, perceived great effort at work, and low self-efficacy. CONCLUSIONS: These findings can contribute in discussion about disability prevention and interventions to assure mental health care for workers.

[The frequency of adverse reactions to sulfamethoxazole with trimethoprim and risk factors in HIV patients]. / Frecuencia de reacciones adversas a sulfametoxazol con trimetoprima y factores de riesgo en pacientes con VIH.

BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMZ) is the long-term use antimicrobial of choice in the prevention and treatment of opportunistic germs in patients with acquired immunodeficiency syndrome (AIDS) in whom the frequency of ADR (adverse drug reactions) is of 30% to 50 %. OBJECTIVE: To determine the adverse reactions to TMP-SMZ and their risk factors in AIDS patients. METHODS: The patients included in the study were older than 18 years of age, admitted from January 2018 to May 2019 with a confirmed diagnosis of HIV, and had had adverse drug reactions; 319 files were reviewed. RESULTS: A frequency of 13.16 % in adverse reactions was reported; out of 42 patients with ADR, 23 had had ADR to TMP-SMZ (54.76 %). The highest rate of adverse reactions was represented by a rash, with 56.5 %, followed by angioedema, with 21.73 %, and nettle rash, with 17.39 %. The risk factors were: infectious comorbidity (OR = 2.6) and CD4 count < 100 (OR = 6.9), without statistical significance. The dose of TMP/SMZ was a risk factor (OR = 12.7) with p = 0.017. CONCLUSIONS: TMP-SMZ used in AIDS patients reached 54 % of the adverse drug reactions, and the dose of this medication was a risk factor.

Antecedentes: Trimetoprima-sulfametoxazol (TMP-SMZ) es el antimicrobiano de elección y de uso prolongado en la prevención y tratamiento de infecciones por gérmenes oportunistas en los pacientes con síndrome de inmunodeficiencia adquirida (sida), en quienes la frecuencia de reacciones adversas a medicamentos es de 30 a 50 %. Objetivo: Determinar las reacciones adversas a TMP-SMZ y sus factores de riesgo en pacientes con sida. Métodos: Se incluyeron pacientes mayores de 18 años con diagnóstico confirmado de infección por VIH y que presentaron reacción adversa a fármacos, de enero de 2018 a mayo de 2019. Se revisaron 319 expedientes. Resultados: Se reportó 13.16 % de reacciones adversas; de 42 pacientes con reacciones adversas a medicamentos, 23 fueron a TMP-SMZ (54.76 %). El rash representó 56.5 % de las reacciones adversas, el angioedema 21.73 % y la urticaria 17.39 %. Los factores de riesgo fueron la comorbilidad infecciosa (RM = 2.6) y la cuenta de CD4 < 100 (RM = 6.9), sin significación estadística; la dosis de TMP-SMZ fue un factor de riesgo (RM = 12.7), con p = 0.017. Conclusiones: El TMP-SMZ en los pacientes con sida ocasionó 54 % de las reacciones adversas a medicamentos y la dosis fue un factor de riesgo.

Resiliência e capacidade para o trabalho em trabalhadores de enfermagem / Resilience and work ability in nursing workers / Resiliencia y capacidad laboral en trabajadores de enfermería

Objetivo: verificar a associação da resiliência com a capacidade para o trabalho em trabalhadores de enfermagem. Método: estudo transversal realizado com 375 trabalhadores de enfermagem de um hospital universitário, na cidade de São Paulo, Brasil, por meio de três instrumentos autoaplicáveis: um para caracterização sociodemográfica e profissional, a Escala de Resiliência e o Índice de Capacidade para o Trabalho. Os dados foram analisados por meio de regressão linear múltipla. O projeto foi aprovado por Comitê de Ética em Pesquisa da instituição. Resultados: Entre os trabalhadores participantes, 15,2% apresentaram baixa resiliência e 30,4% mostraram capacidade para o trabalho comprometida. Quanto maior o escore do Índice de Capacidade para o Trabalho, maior a pontuação da Escala de Resiliência (=0,722; p<0,001). Conclusão: a resiliência foi associada de forma positiva à capacidade para o trabalho

Objective: to verify the association of resilience with work ability in nursing workers. Method: cross-sectional study carried out with 375 nursing workers from a university hospital in the city of São Paulo, Brazil, using three self-applicable instruments: one for sociodemographic and professional characterization, the Resilience Scale and the Work Ability Index. Data were analyzed using multiple linear regression analysis. The research project was approved by the Institution's Research Ethics Committee. Results: Among participants workers, 15.2% showed low resilience and 30.4% have some level of impaired work ability. The higher the Work Ability Index score, the higher the Resilience Scale score (=0.722; p<0.001). Conclusion: resilience was positively associated with the work ability.

Objetivo: verificar la asociación de resiliencia con capacidad laboral en trabajadores de enfermería. Método: estudio transversal realizado con 375 trabajadores de enfermería de un hospital universitario en la ciudad de São Paulo, Brasil, utilizando tres instrumentos auto-aplicables: uno para caracterización sociodemográfica y profesional, la Escala de Resiliencia y el Índice de Capacidad Laboral. Los datos se analizaron mediante análisis de regresión lineal múltiple. El proyecto de investigación fue aprobado por el Comité de Ética de Investigación de la Institución. Resultados: Entre los trabajadores participantes, el 15.2% mostró baja capacidad de recuperación y el 30.4% tiene algún nivel de capacidad laboral deteriorada. Cuanto más alto sea el puntaje del Índice de Habilidad de Trabajo, más alto será el puntaje de la Escala de Resiliencia (=0.722; p<0.001). Conclusión: la resiliencia se asoció positivamente con la capacidad de trabajo.

Work Ability and Job Survival: Four-Year Follow-Up.

BACKGROUND: Employees with impaired work ability might be at higher risk of remaining shorter in the job than those with adequate work ability. The aim of the study was to establish whether work ability plays a role in job survival. METHODS: Four-year follow-up (2008-2012) study of 1037 employees of a hospital in São Paulo, Brazil. Work ability was categorized as "adequate" or "impaired". Employment status at the end of follow-up was categorized as active, resignation or dismissal. Survival analysis was performed using the Kaplan-Meier method and the Cox proportional-hazards model. RESULTS: About 78.9% of the participants had adequate and 21.1% impaired work ability. Job survival was longer for the participants with adequate work ability independently from the type of job termination (p < 0.001). The odds of job termination were higher for the participants with impaired work ability (p < 0.001) who either resigned (hazard ratio-HR = 1.58) or were dismissed (HR = 1.68). CONCLUSION: Job survival was shorter for the employees with impaired work ability independently from the type of job termination. It was also shorter for the employees who were dismissed compared to those who resigned. Duration in the job might be extended through actions to enhance work ability.

Validity and reliability of the Brazilian version of the Johns Hopkins Fall Risk Assessment Tool to assess the risk of falls. / Validade e confiabilidade da versão brasileira da Johns Hopkins Fall Risk Assessment Tool para avaliação do risco de quedas.

OBJECTIVE: To evaluate the validity and reliability of the Johns Hopkins Fall Risk Assessment Tool (JH-FRAT), which assesses the risk of falls in hospitalized inpatients. METHOD: Study with 297 patients at a hospital in São Paulo, using retrospective data form 2014. Validity was assessed by accuracy (sensitivity, specificity, positive predictive value - PPV and negative predictive value - NPV) and discriminant analysis (comparison of patients with and without falls in relation to the scale items and comparison of previous risk situations in relation to the injury). The χ2 test and Fisher's exact test were used. Reliability was assessed by reproducibility between methods and interobserver test-retest comparison in a subsample of 60 patients. We used the Kappa, quadratic weighted Kappa and PABAK statistics. RESULTS: Sensitivity was 97.0%, specificity was 6%, PPV was 36.2% and NPV was 90.6%. Five of the eight items of the scale and the overall classification showed risk discrimination capability (p < 0.050). The risk of previous situations did not discriminate the injury resulting from the falls (p = 0.557). Reproducibility between methods was substantial (PABAK = 0.71). The interobserver reproducibility ranged between items (PABAK 0.25 to 1.00) and was substantial to the overall risk classification (PABAK = 0.71). CONCLUSION: JH-FRAT showed validity and reliability expected of a screening tool for risk of falls, and it can contribute to the implementation of fall management strategies in hospitals.

OBJETIVO: Avaliar a validade e a confiabilidade da escala Johns Hopkins Fall Risk Assessment Tool (JH-FRAT) para avaliação do risco de quedas em pacientes hospitalizados. MÉTODO: Estudo retroativo com 297 pacientes de um hospital privado de São Paulo usando dados de 2014. A validade foi avaliada por meio da acurácia (sensibilidade, especificidade, valores preditivos positivo - VPP e negativo - VPN), da validade de critério, verificando-se as associações entre a classificação do risco pelas escalas JH-FRAT e Morse, e da análise discriminante (comparação dos pacientes com e sem quedas em relação aos itens da escala e verificação de situações prévias de risco em relação ao dano ocorrido). Foram utilizados os testes de associação χ2. A confiabilidade foi avaliada por meio da reprodutibilidade teste-reteste interobservadores, usando as estatísticas Kappa ponderado quadrático e prevalence-adjusted and bias-adjusted Kappa (PABAK). RESULTADOS: A sensibilidade foi de 97,0%, a especificidade, 14,6%, o VPP, 36,2%, e o VPN, 90,6%. A análise de critério mostrou associação (p < 0,0001) entre as avaliações pelas duas escalas. Cinco dos oito itens da escala e a classificação geral mostraram capacidade de discriminação do risco (p < 0,050). A reprodutibilidade interobservadores variou entre itens (PABAK de 0,25 a 1,00) e foi substancial na classificação do risco global (PABAK = 0,71). CONCLUSÃO: A JH-FRAT apresentou validade e confiabilidade esperadas para um instrumento de triagem do risco de quedas, podendo contribuir na aplicação de estratégias para a gestão de quedas em hospitais.

Work Ability as Determinant of Termination of Employment: To Resign or Be Dismissed?

OBJECTIVE: The aim of this study was to investigate whether work ability plays a role in termination of employment (resignation or dismissal) in the short-to-medium run. METHODS: Four-year cohort study with 1060 Brazilian hospital workers. The outcome was final employment status (active, resignation, or dismissal). Multinomial models were fit. RESULTS: At the end of follow-up, 14.3% of the workers had resigned and 34.0% were dismissed. Impaired work ability was a risk factor for dismissal (relative risk ratio  = 1.39), but not for resignation. Also, job strain, age and sex, family income, nutritional status, and workshift were associated with employment termination. CONCLUSIONS: Impaired work ability was a risk factor for dismissal but not for resignation in the short-to-medium run. Individual and occupational characteristics also contributed to employment termination. Improvement of work ability and working conditions are recommended to prevent quitting the job.