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Appl Radiat Isot ; 167: 109353, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33039761

ABSTRACT

In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector.


Subject(s)
Boron Neutron Capture Therapy/methods , Radiometry/methods , Autoradiography , Cell Line, Tumor , Dose-Response Relationship, Radiation , Humans
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