ABSTRACT
OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects the joints and other organs, including the development of the former in a growing child. This study aimed to evaluate the feasibility of texture analysis (TA) based on magnetic resonance imaging (MRI) to provide biomarkers that serve to identify patients likely to progress to temporomandibular joint damage by associating JIA with age, gender and disease onset age. METHODS: The radiological database was retrospectively reviewed. A total of 45 patients were first divided into control group (23) and JIA group (22). TA was performed using grey-level co-occurrence matrix (GLCM) parameters, in which 11 textural parameters were calculated using MaZda software. These 11 parameters were ranked based on the p value obtained with ANOVA and then correlated with age, gender and disease onset age. RESULTS: Significant differences in texture parameters of condyle were demonstrated between JIA group and control group (p < 0.05). There was a progressive loss of uniformity in the grayscale pixels of MRI with an increasing age in JIA group. CONCLUSIONS: MRI TA of the condyle can make it possible to detect the alterations in bone marrow of patients with JIA and promising tool which may help the image analysis.
Subject(s)
Arthritis, Juvenile , Mandibular Condyle , Child , Humans , Mandibular Condyle/diagnostic imaging , Mandibular Condyle/pathology , Arthritis, Juvenile/diagnostic imaging , Arthritis, Juvenile/complications , Retrospective Studies , Temporomandibular Joint , Magnetic Resonance Imaging/methodsABSTRACT
OBJECTIVE: The aim of this study was to investigate the TMJ components in patients with juvenile idiopathic arthritis (JIA) and to compare them with a control group based on magnetic resonance imaging (MRI) measurements. METHODS: This study comprised an assessment of MRI measurements of 96 temporomandibular joints (TMJ) following classification criteria set by the International League of Associations for Rheumatology (ILAR). Three measurements were considered for study: condyle excursion angle (CEA), height of articular eminence (HAE) and inclination of articular eminence (IAE). All TMJs were assessed by linear measurements made by using the OnDemand 3D software. The comparison between the groups was performed by using Mann-Whitney's test. RESULTS: Lower measurement values were found for IAE, HAE and CEA in JIA patients (P-values < 0.001, 0.005 and < 0.001, respectively). CONCLUSION: The study showed the differences in MRI measurements between JIA patients and controls, with the former with the lowest indices.
Subject(s)
Arthritis, Juvenile , Temporomandibular Joint Disorders , Arthritis, Juvenile/diagnostic imaging , Arthritis, Juvenile/pathology , Humans , Magnetic Resonance Imaging/methods , Retrospective Studies , Temporomandibular Joint/diagnostic imaging , Temporomandibular Joint Disorders/diagnostic imagingABSTRACT
O objetivo deste estudo foi verificar a variação do volume do disco articular da ATM em pacientes com DTM e em indivíduos de controle, correlacionando-a com diagnóstico de imagem de RM e com dados clínicos. Foram analisados 29 exames de ressonância magnética entre pacientes e controles, totalizando 58 ATMs, em cortes sagitais sequenciais das imagens de RM. O software livre MRIcro foi utilizado para delineamento manual dos limites anatômicos do disco articular e obtenção o volume do disco. Para analisar a correlação entre os volumes dos discos e as variáveis clínicas e por imagem, empregou-se o teste de Kruskal-Wallis. Para caracterizar e comparar as variáveis entre gênero e idade foi aplicado o Teste t de Student independente. Observou-se uma correlação entre o deslocamento do disco (p-valor = 0.001 para ATM direita e p-valor = 0.002 para ATM esquerda) e o volume do disco, que aumentou significativamente no grupo de pacientes. Não foi encontrada associação significativa entre gênero e volume dos discos direito e esquerdo (respectivamente; p-valor = 0,640 e 0,390). Concluiu-se que o volume do disco articular aumentou com a presença de desarranjo intra-articular.
The objective of this study was to measure the variation in the volume of temporomandibular joint disc in the patients with TMD compared with control individuals, in magnetic resonance images and clinical data. Twenty nine subjects have been analyzed between patients and control, totalizing 58 TMJ's in MR sequential sections. The software MRICro was used to anatomic delineation and to acquire the volume. Statistical analysis was conducted using Kruskal-Wallis test to correlate between disc volumes and clinical imaging variables. To compare the dependence on variables gender and age, Student Independence test was used. A correlation has been detected between disc displacement (p-value = 0.001 for right TMJ and p-value = 0.002 for left TMJ) and disc volume, which exhibited significant increase in patients. No significant correlation has been observed between gender and left and right disc volumes (respectively; p-value = 0,640 e 0,390). It was concluded that joint disc volume increased with the presence of internal derangement.
