ABSTRACT
OBJECTIVE: The aim of this study was measure and compare Secretory IgA levels in the respiratory tract. DESIGN: Cross-sectional study. SETTING: Neumology Department of General Hospital. La Raza Medical Center Mexico. MATERIAL AND METHOD: There were 35 volunteers. Samples of sputum, washings nasopharyngeal and bronchial was obtained from thirty five patients with COPD. Measurement of SIgA levels was performed by nephelometric technique. Results is reported as ratio of SIgA concentration/Total proteins concentration named SIgA relative concentration. Correlation index was obtained of three type of samples. RESULTS: The SIgA values of sputum, washings nasopharyngeal and bronchial was similar similar +/- 0.011, 0.064 +/- 0.007 and 0.082 +/- 0.017 respectively). Multiple correlation was r = 0.508 (p < 0.01).
Subject(s)
Bronchoalveolar Lavage Fluid/immunology , Immunoglobulin A, Secretory/analysis , Lung Diseases, Obstructive/immunology , Nasopharynx/immunology , Sputum/immunology , Adolescent , Adult , Aged , Bronchitis/immunology , Chronic Disease , Cross-Sectional Studies , Humans , Male , Middle Aged , Nephelometry and TurbidimetryABSTRACT
The present study was realized to evaluate the effectiveness, security and tolerability of slow release micro pellets theophylline, in a group of 168 asthmatic children, between 2 and 15 years old. The improvement of the symptoms was obtained, since the treatment began. The final evaluation was considered excellent and good in 86.90% of the cases, and the tolerability, excellent and good in 94.64% of the patients. In conclusion the slow-release micro pellets theophylline is a very effective and secure drug, with a very good tolerability for the treatment of the asthmatics in pediatric age.