Immunization against covid-19 and mortality in hospitalized patients: a retrospective cohort.

OBJECTIVE: To evaluate the effectiveness of vaccines developed against covid-19 in reducing mortality in people hospitalized with severe acute respiratory syndrome (SARS) caused by SARS-CoV-2. METHODS: This is a retrospective cohort that evaluated risk factors and the effectiveness of the two-dose vaccination schedule in reducing the mortality of people hospitalized for covid-19 in the state of Paraíba from February to November 2021. The explanatory variables were vaccination status, presence of comorbidities, socioeconomic and demographic characteristics. Descriptive analyses and bivariate and multivariable logistic regression were performed. RESULTS: Most hospitalizations and deaths occurred until May 2021. The percentage of patients with a complete vaccination schedule was similar across patients admitted to public and private hospitals and higher in residents of less developed municipalities. Multivariable analysis demonstrated that women (OR = 0.896; 95%CI 0.830-0.967) and people admitted to private hospitals (OR = 0.756; 95%CI 0.679-0.842) were less likely to die. Presence of any comorbidity (OR = 1.627; 95%CI 1.500-1.765) and age ≥ 80 years (OR = 7.426; 95%CI 6.309-8.741) were risk factors for death. Patients with complete vaccination schedule at the time of admission were 41.7% less likely to die (OR = 0.583; 95% CI 0.501-0.679) from covid-19 in the adjusted analysis, as compared to unvaccinated patients. CONCLUSIONS: The study reveals that immunization was effective in reducing the likelihood of death from covid-19. The results suggest that greater vaccination coverage in the first half of 2021 would prevent thousands of deaths in the country.

Immunization against covid-19 and mortality in hospitalized patients: a retrospective cohort / Imunização contra covid-19 e mortalidade em pacientes hospitalizados: coorte retrospectiva

ABSTRACT OBJECTIVE To evaluate the effectiveness of vaccines developed against covid-19 in reducing mortality in people hospitalized with severe acute respiratory syndrome (SARS) caused by SARS-CoV-2. METHODS This is a retrospective cohort that evaluated risk factors and the effectiveness of the two-dose vaccination schedule in reducing the mortality of people hospitalized for covid-19 in the state of Paraíba from February to November 2021. The explanatory variables were vaccination status, presence of comorbidities, socioeconomic and demographic characteristics. Descriptive analyses and bivariate and multivariable logistic regression were performed. RESULTS Most hospitalizations and deaths occurred until May 2021. The percentage of patients with a complete vaccination schedule was similar across patients admitted to public and private hospitals and higher in residents of less developed municipalities. Multivariable analysis demonstrated that women (OR = 0.896; 95%CI 0.830-0.967) and people admitted to private hospitals (OR = 0.756; 95%CI 0.679-0.842) were less likely to die. Presence of any comorbidity (OR = 1.627; 95%CI 1.500-1.765) and age ≥ 80 years (OR = 7.426; 95%CI 6.309-8.741) were risk factors for death. Patients with complete vaccination schedule at the time of admission were 41.7% less likely to die (OR = 0.583; 95% CI 0.501-0.679) from covid-19 in the adjusted analysis, as compared to unvaccinated patients. CONCLUSIONS The study reveals that immunization was effective in reducing the likelihood of death from covid-19. The results suggest that greater vaccination coverage in the first half of 2021 would prevent thousands of deaths in the country.

RESUMO OBJETIVO Avaliar a efetividade das vacinas desenvolvidas contra a covid-19 na redução da mortalidade em pessoas internadas com síndrome respiratória aguda grave (SRAG) causada pelo SARS-CoV-2. MÉTODOS Trata-se de uma coorte retrospectiva que avaliou fatores de riscos e a efetividade do esquema vacinal com duas doses na redução da mortalidade de pessoas internadas por covid-19 no estado da Paraíba entre fevereiro e novembro de 2021. As variáveis explicativas foram situação vacinal, presença de comorbidades, características socioeconômicas e demográficas. Foram realizadas análises descritivas e regressão logística bivariada e multivariável. RESULTADOS A maior parte das internações e óbitos ocorreram até maio de 2021. O percentual de pacientes com esquema vacinal completo foi similar entre pacientes internados em hospitais públicos e privados e superior em residentes de municípios com menor desenvolvimento. A análise multivariável demonstrou que mulheres (OR = 0,896; IC95% 0,830-0,967) e pessoas internadas em hospitais privados (OR = 0,756; IC95% 0,679-0,842) apresentaram menor chance de morte. A presença de alguma comorbidade (OR = 1,627; IC95% 1,500-1,765) e idade ≥ 80 anos (OR = 7,426; IC95% 6,309-8,741) foram fatores de risco de óbito. Pacientes com esquema vacinal completo no momento da internação apresentaram uma chance 41,7% menor de morte (OR = 0,583; IC95% 0,501-0,679) por covid-19 na análise ajustada, quando comparados com pacientes não vacinados. CONCLUSÕES O estudo revela que a imunização foi efetiva na redução da chance de óbito por covid-19. Os resultados sugerem que uma maior cobertura vacinal no primeiro semestre de 2021 evitaria milhares de mortes no país.

'Scorched Earth: The portrait of health in Brazil after the Bolsonaro's administration and the first 100 days of the Lula Government in health'.

This article is a rejoinder to the rebuttal letter authored by Jair Bolsonaro's former Minister of Health and Secretary of Primary Care to our initial article, 'From Bolsonaro to Lula: The opportunity to rebuild universal healthcare in Brazil during the government transition,' published in the International Journal of Health Planning and Management. We aim to refute the claims that we consider unsubstantiated and disconnected from reality, while reiterating the risks posed by authoritarian and antidemocratic far-right governments, such as Bolsonarism in Brazil, to the sustainability and resilience of universal health systems. This political threat is gaining momentum across several countries worldwide, thereby endangering the Democratic Rule of Law, institutions, and social policies. Furthermore, we emphasise the significant actions implemented during the first 100 days of President Lula's government, which align with the priorities established during the governmental transition process and strengthen the prospects of reconstructing and fortifying the Brazilian universal health system.

From Bolsonaro to Lula: The opportunity to rebuild universal healthcare in Brazil in the government transition.

This paper takes the government transition that took place between 2022 and 2023 in Brazil as a case study and aims to analyse how a cycle of radical right-wing populist government acted to dismantle Brazil's national health system foundations. It describes how governance was built based on political-clientelism and market-privatising interests and on the adoption of long-term fiscal austerity policies, whose results are public defunding and weakening and disorganisation of the country's national health system, with a significant worsening of health indicators and the capacity to respond to the population health needs. The lessons from recent experience in Brazil should serve as learning and a source of academic and political reflection, since there is an ongoing international movement and signs of rise of radical right-wing populist regimes in several countries, which endanger the Democratic Rule of Law, institutions, and social policies. It allows putting into perspective how political cycles of this nature can affect national universal health systems, including those that have experienced substantial progress towards universal access and universal health coverage. Keeping in mind the Brazilian experience, it was possible to observe the progressive structuring of a radical right-wing neo-populism and in the sanitarian.

Health systems resilience: is it time to revisit resilience after COVID-19?

The concept of health system resilience has been challenged by the COVID-19 pandemic. Even well-established health systems, considered resilient, collapsed during the pandemic. To revisit the concept of resilience two years and a half after the initial impact of COVID-19, we conducted a qualitative study with 26 international experts in health systems to explore their views on concepts, stages, analytical frameworks, and implementation from a comparative perspective of high- and low-and-middle-income countries (HICs and LMICs). The interview guide was informed by a comprehensive literature review, and all interviewees had practice and academic expertise in some of the largest health systems in the world. Results show that the pandemic did modify experts' views on various aspects of health system resilience, which we summarize and propose as refinements to the current understanding of health systems resilience.

Social determinants of health in Brazil during the COVID-19 pandemic: strengths and limitations of emergency responses.

Economic crises often expose the most vulnerable to higher health risks and tend to exacerbate existing inequalities. The Social Determinants of Health (SDoH) framework illustrates many layers of inequalities that would affect outcomes of the COVID-19 pandemic. The impacts of emergency policy responses considering the SDoH framework are important for all sectors in policymaking. However, its assessment in Global South countries is limited, due to high informality rates and data availability. We address this gap using a unique dataset that allows for the analysis of occupational categories before and after the COVID-19 pandemic in Brazil, incorporating the emergency assistance provided in 2020. Results show that, although labor earnings fell 4% for the self-employed at each death from COVID-19, increasing unemployment and inactivity among the typically most vulnerable, those effects were offset by emergency policies, reducing poverty. Groups often considered less vulnerable, such as formal employees, had an increase. The policy responses to this shock served then as a leveler of previous SDoH, despite ignoring the health-risk gradient there is along the income distribution. A poverty rebound that ensued after the sudden discontinuation of those policies is a lesson for future crises, and on how SDoH inequalities should be addressed.

Inovações na Gestão em Saúde e a Resiliência do SUS: a experiência capixaba na resposta à Covid-19 / Innovations in Health Management and the Resilience of the SUS: the Espírito Santo experience in the response to Covid-19

A pandemia da Covid-19 foi a maior prova a que os sistemas de saúde e já foram submetidos. Dentre as lições deixadas pela pandemia está a necessidade de os países fortalecerem a resiliência de seus sistemas de saúde. Além da estrutura organizacional, a resiliência dos sistemas de saúde depende de elementos como a preparação para rápida resposta a ameaças a saúde coletiva, liderança para tomada de decisões, coordenação de múltiplas ações, mobilização de recursos para gestão da crise e, sobretudo, aprendizagem com a resposta à crise. Nesse sentido, analisar como os governos responderam à Covid-19 é essencial para identificar eventuais falhas e sucessos que possam oferecer lições para a ampliar a capacidade de resiliência e aprimorar a estrutura organizacional dos sistemas de saúde. Dentro dessa perspectiva apresenta-se esta publicação, que trata de uma análise descritiva de projetos e inovações na gestão em saúde implementados pelo governo do Espírito Santo, em partícula pela Secretaria Estadual de Saúde, que contribuíram para ampliar a capacidade de resiliência do SUS na resposta à Covid-19. Os resultados da análise da experiência capixaba estão alinhados com achados de outros estudos internacionais, que chegam à conclusão de que novos instrumentos, estratégias e liderança, são cruciais para que um novo ciclo político de organização do SUS, conduzido pelos governos estaduais, se desenvolva. Nesse contexto, o esforço do Espírito Santo não deve ser considerado apenas um programa de modernização e aprimoramento da gestão, mas uma iniciativa concreta de transformação da direcionalidade da atuação dos governos estaduais para tornar sua ação mais efetiva e coerente com os valores que fundamentam o SUS frente aos desafios contemporâneos enfrentados pelo setor saúde.

Políticas de ampliação do acesso ao ensino superior e mudança no perfil de egressos de medicina no Brasil: um estudo transversal / Policies for expanding access to higher education and changing the profile of medical graduates in Brazil: a cross-sectional study

Resumo Este estudo avalia o impacto de políticas de ampliação do acesso ao ensino superior na redução de iniquidades no perfil dos egressos de cursos médicos no Brasil. Estudo transversal que utiliza dados do Censo da Educação Superior de 2018. Foram realizadas análises para identificar associação entre ser beneficiário da Lei de Cotas, do Programa Universidade para Todos ou do Fundo de Financiamento Estudantil e três marcadores: nascimento em município de pequeno porte, ser não-branco ou ter cursado ensino médio em escola pública. Realizamos análises utilizando teste de qui-quadrado de Pearson e análise multivariada através de regressão de Poisson. Houve associação significativa entre ser beneficiário destas políticas e ser egresso não branco, ter nascido em município de pequeno porte e ser egresso de escola pública no ensino médio. Todas as políticas apresentaram resultados de Razões de Prevalências (RP) ajustadas superiores a um e com significância estatística. A Lei de Cotas foi a política mais efetiva com RP=1,92 para ser egresso não-branco, RP=6,66 para ter estudado ensino médio em escola pública e RP=1,08 para ter nascido em município de pequeno porte. Apesar destes resultados, estes grupos continuam sub-representados nos cursos médicos e na composição da força de trabalho.

Abstract This study assesses the effectiveness of policies to expand access to higher education in reducing inequities in the profile of graduates from medical courses in Brazil. This work consists of a cross-sectional study using data from the 2018 Higher Education Census. Analyses were carried out to identify the association between being a beneficiary of the Quota Law, the University for All Program, or the Student Financing Fund and three markers: born in a small-sized municipality, being non-white, or having attended high school in a public school. Analyses were performed using Pearson's chi-square test, and multivariate analysis was conducted using Poisson regression. A significant association was found between being a beneficiary of these policies and being a non-white graduate, who was born in a small town and who had studied in a public high school. All policies presented adjusted Prevalence Ratio (PR), which demonstrated an association with statistical significance. The Quota Law was the most effective policy, with RP=1.92 for non-white graduates, RP=6.66 for having studied in a public high school, and RP=1.08 for being born in a small town. Despite these results, these groups remain underrepresented in medical courses and in the workforce.

Policies for expanding access to higher education and changing the profile of medical graduates in Brazil: a cross-sectional study. / Políticas de ampliação do acesso ao ensino superior e mudança no perfil de egressos de medicina no Brasil: um estudo transversal.

This study assesses the effectiveness of policies to expand access to higher education in reducing inequities in the profile of graduates from medical courses in Brazil. This work consists of a cross-sectional study using data from the 2018 Higher Education Census. Analyses were carried out to identify the association between being a beneficiary of the Quota Law, the University for All Program, or the Student Financing Fund and three markers: born in a small-sized municipality, being non-white, or having attended high school in a public school. Analyses were performed using Pearson's chi-square test, and multivariate analysis was conducted using Poisson regression. A significant association was found between being a beneficiary of these policies and being a non-white graduate, who was born in a small town and who had studied in a public high school. All policies presented adjusted Prevalence Ratio (PR), which demonstrated an association with statistical significance. The Quota Law was the most effective policy, with RP=1.92 for non-white graduates, RP=6.66 for having studied in a public high school, and RP=1.08 for being born in a small town. Despite these results, these groups remain underrepresented in medical courses and in the workforce.

Este estudo avalia o impacto de políticas de ampliação do acesso ao ensino superior na redução de iniquidades no perfil dos egressos de cursos médicos no Brasil. Estudo transversal que utiliza dados do Censo da Educação Superior de 2018. Foram realizadas análises para identificar associação entre ser beneficiário da Lei de Cotas, do Programa Universidade para Todos ou do Fundo de Financiamento Estudantil e três marcadores: nascimento em município de pequeno porte, ser não-branco ou ter cursado ensino médio em escola pública. Realizamos análises utilizando teste de qui-quadrado de Pearson e análise multivariada através de regressão de Poisson. Houve associação significativa entre ser beneficiário destas políticas e ser egresso não branco, ter nascido em município de pequeno porte e ser egresso de escola pública no ensino médio. Todas as políticas apresentaram resultados de Razões de Prevalências (RP) ajustadas superiores a um e com significância estatística. A Lei de Cotas foi a política mais efetiva com RP=1,92 para ser egresso não-branco, RP=6,66 para ter estudado ensino médio em escola pública e RP=1,08 para ter nascido em município de pequeno porte. Apesar destes resultados, estes grupos continuam sub-representados nos cursos médicos e na composição da força de trabalho.

[Prevalence rates and inequalities in access to medicines by users of the Brazilian Unified National Health System in 2013 and 2019]. / Prevalências e desigualdades no acesso aos medicamentos por usuários do Sistema Único de Saúde no Brasil em 2013 e 2019.

The study aimed to analyze and compare the prevalence of access to medicines and associated factors among users of the Brazilian Unified National Health System (SUS). The authors analyzed data from the 2013 and 2019 editions of the Brazilian National Health Survey, a nationwide health study, representative of the Brazilian population. The outcomes were: (1) obtaining from the SUS all the medicines prescribed during care received in the SUS itself in the two weeks prior to the interview (2) and obtaining all the medicines, regardless of the source. Demographic and socioeconomic characteristics were included as independent variables. In 2019, 29.7% of the interviewees obtained all the prescribed medicines from the SUS, 81.8% obtained all the medicines in general (considering all sources), and 56.4% paid some amount for the medicines. The proportion who did obtain any medicine from the SUS and that made some out-of-pocket payment increased from 2013 to 2019. The likelihood of obtaining all the medicines in the SUS was higher among the poorest, and that of obtaining the medicines regardless of source was higher among the wealthiest. Approximately two out of three persons that were unable to access all the medicines reported difficulties obtaining them in services funded by the public sector. There was an increase in out-of-pocket expenditure on medicines in Brazil and a reduction in access through the SUS, among users of the system.

O objetivo do estudo foi analisar e comparar a prevalência, a forma de obtenção e os fatores associados ao acesso a medicamentos entre usuários do Sistema Único de Saúde (SUS) no Brasil. Foram analisados os dados das edições 2013 e 2019 da Pesquisa Nacional de Saúde, estudo de abrangência nacional e representativo da população brasileira. Os desfechos foram: (1) a obtenção total, por meio do SUS, dos medicamentos prescritos em atendimentos em saúde realizados no próprio SUS nas duas semanas anteriores à entrevista, e (2) a obtenção total dos medicamentos independentemente da fonte. Características demográficas e socioeconômicas foram incluídas como variáveis independentes. Em 2019, observou-se que 29,7% dos entrevistados obtiveram no SUS todos os medicamentos prescritos, que 81,8% tiveram acesso total aos medicamentos quando consideradas todas as fontes de obtenção e que 56,4% pagaram algum valor pelos medicamentos. A proporção de pessoas que não obtiveram nenhum medicamento no SUS e que efetuaram algum desembolso direto aumentou entre 2013 e 2019. A probabilidade de obter todos os medicamentos no SUS foi maior entre os mais pobres, e de consegui-los, independentemente da fonte, foi maior entre os mais ricos. Dentre as pessoas que não conseguiram acesso a todos os medicamentos, aproximadamente duas em cada três indicaram como principal motivo dificuldades de obtenção encontradas em serviços financiados pelo setor público. Verificou-se ampliação do desembolso direto para compra de medicamentos no Brasil e redução de acesso pelo SUS entre usuários do sistema.

El objetivo de este estudio fue analizar y comparar la prevalencia, la forma de obtención y los factores asociados al acceso a los medicamentos entre los usuarios del Sistema Único de Salud (SUS) en Brasil. Se analizaron los datos de las ediciones 2013 y 2019 de la Encuesta Nacional de Salud, un estudio de cobertura nacional y representativo de la población brasileña. Los resultados fueron: (1) la obtención total, a través del SUS, de los medicamentos prescritos en los servicios de salud realizados en el propio SUS en las dos semanas anteriores a la entrevista, y (2) la obtención total de los medicamentos independientemente de la fuente. Las características demográficas y socioeconómicas se incluyeron como variables independientes. En 2019 se observó que el 29,7% de los entrevistados obtuvo todos los medicamentos prescritos en el SUS, que el 81,8% tuvo acceso total a los medicamentos al considerar todas las fuentes de obtención y que el 56,4% pagó por los medicamentos. La proporción de personas que no obtuvieron ningún medicamento en el SUS y que realizaron algún gasto directo aumentó entre 2013 y 2019. Entre los pobres, la probabilidad de obtener todos los medicamentos del SUS fue mayor, y entre los más ricos también fue mayor esta obtención independientemente de la fuente. Entre las personas que no pudieron acceder a todos los medicamentos, aproximadamente dos de cada tres indicaron como razón principal las dificultades que se encuentran en los servicios financiados con fondos públicos. Hubo un aumento del gasto directo para la compra de medicamentos en Brasil y una reducción del acceso a través del SUS entre los usuarios del sistema.

Integração ensino-serviço na implantação de um curso de medicina no Paraná / Implementation of mental health care with the CIHP approach in primary care

Integrar o ensino de medicina e a rede municipal de saúde, segundo inúmeros estudos, contribui para a melhoria da formação médica e da assistência à saúde da comunidade atendida. O presente estudo analisou a integração ensino-serviço na Atenção Primária à Saúde (APS) entre o curso de medicina do Campus Toledo da Universidade Federal do Paraná (UFPR) e a Secretaria Municipal de Saúde (SMS) de Toledo, também no Paraná. Foram realizadas doze entrevistas semiestruturadas com participantes da gestão municipal, coordenação do curso de medicina de Toledo, estudantes de medicina, professores que têm aulas práticas na APS e profissionais de saúde da APS que recebem alunos. A hermenêutica foi utilizada na análise dos dados. Entre as dificuldades apontadas observou-se: estrutura física inadequada das Unidades Básicas de Saúde (UBS), comunicação parcial entre a SMS e a universidade, falta de um Contrato Organizativo de Ação Pública de Ensino-Saúde (COAPES) pactuado etc. Como sugestões para a melhoria do processo de integração, destacaram-se a capacitação da equipe de saúde e o planejamento da infraestrutura física.

Integrating medical education and the municipal health network, according to numerous studies, contributes to improving medical training and health care in the community served. This study analyzed the teaching-service integration in primary health care (PHC) between the medical course at the Toledo Campus of the Federal University of Paraná (UFPR) and the Municipal Health Department (SMS) of Toledo, PR. Twelve semi-structured interviews were carried out with participants from the municipal administration, the coordination of the Toledo medicine course, medicine students, teachers who teach practical classes at PHC, and health professionals from PHC who receive students. Hermeneutics was used in the data analysis. Among the difficulties pointed out, it was observed: the inadequate physical structure of the Basic Health Units (UBS), partial communication between the SMS and the university, thelack of an Organizational Contract for Public Education-Health Action (COAPES) agreed upon, etc. As suggestions for improving the integration process, the training of the health team and the planning of the physical infrastructure were highlighted.

Brazil's health system functionality amidst of the COVID-19 pandemic: An analysis of resilience.

Background: As of December 31, 2020, Brazil had the second-highest burden of COVID-19 worldwide. Given the absence of federal government coordination, it was up to the local governments to maintain healthcare provision for non-COVID health issues. In this descriptive study, we aimed to discuss the SUS functionality and resilience, describing the impact of the pandemic on non-COVID health services delivery while considering the regional inequalities of the allocation of financing health system, health infrastructure and health workforce. Methods: We used input-output framework based on the World Health Organization (WHO) Health System Building Blocks to estimate health system functionality and resilience. An ecological assessment was designed to calculated mean relative changes to compare the first year of the pandemic in Brazil with the previous one. All data used in this study were anonymized and made available by the Brazilian Ministry of Health. Input indicators were categorized in health system financing (federal funding received as well as expenditure of both state and city governments), health system's infrastructure (hospital beds) and health workforce (healthcare workers positions). Output indicators were categorized into nine different groups of service delivery procedures. To explore the relationship between the variation in procedures with socioeconomic conditions, we used the Socioeconomic Vulnerability Index (SVI). Findings: State governments had a 38·6% increase in federal transfers, while municipal governments had a 33·9% increase. The increase of ICU beds reached its peak in the third quarter of 2020, averaging 72·1% by the end of the year. The country also saw an increase in jobs for registered nurses (13·6%), nurse assistants (8·5%), physiotherapists (7·9%), and medical doctors (4·9%). All procedures underwent expressive reduction: Screenings (-42·6%); Diagnostic procedures (-28·9%); Physician appointments (-42·5%); Low and medium complexity surgeries (-59·7%); High complexity surgeries (-27·9%); Transplants (-44·7%); Treatments and clinical procedures due to injuries of external causes (-19·1%); Irrepressible procedures (-8·5%); and Childbirths (-12·6%). The most significant drop in procedures happened in the first quarter of the pandemic, followed by progressive increase; most regions had not yet recovered by the end of 2020. State-level changes in numbers of procedures point towards a negative trend with SVI. Interpretation: The Brazilian Government did not consider that socioeconomically vulnerable states were at a higher risk of being impacted by the overburden of the health system caused by the COVID-19, which resulted in poorer health system functionality for those vulnerable states. The lack of proper planning to improve health system resilience resulted in the decrease of a quarter of the amount of healthcare procedures increasing the already existing health disparities in the country. Funding: MCTIC/CNPQ/FNDCT/MS/SCTIE/DECIT No 07/2020.

Lessons from the Brazilian radiotherapy expansion plan: A project database study.

Background: The Radiotherapy Expansion Plan for Brazil's Unified Health System (PER-SUS) was an innovative program designed by the Ministry of Health in 2012 to provide improvements to the challenging problem of access to radiotherapy in the country. This study sought to analyze the execution and implementation of installations proposed by PER-SUS, and their capacity to address the problems of radiotherapy access in Brazil. Methods: From the first release (February 2015) until October 2021, all PER-SUS monthly progress reports were retrospectively analyzed. The beneficiary institutions, project location, project status, project type, dates of the progress on the stages, and reasons for cancellations or possible justifications for changing the status were collected. Brazilian geographic data, health care demands, and cancer incidences were correlated. Finally, we performed an Ishikawa diagram and 5W3H methodology, aiming to better understand the findings and to yield possible ways to improve the access to radiotherapy. Findings: After ten years, the PER-SUS project delivered nearly 50% of the planned implementation of radiotherapy equipment. There was a 17% growth in the national number of linear accelerators (LINACS) with PER-SUS, against a 32% increase in cancer incidence in Brazil in the same period. The following points were identified: a high rate of beneficiary exclusions reflecting inappropriate selection or inadequate planning; delays in execution related to bureaucratic obstacles and underestimation of the requirements (logistics/people); early closing of the equipment factory as a result of lack of project prioritization by the Government. Interpretation: Only about 50% of PER-SUS are being carried out. However, delays and exclusions of beneficiaries were observed. The dimension of the need for radiotherapy care in Brazil is greater than considered, and might not be fully attended by PER-SUS. Geographic, epidemiological, logistical, and economic variables could be reevaluated to allow better strategic planning and improvement proposals. PER-SUS could be optimized for the next decade, by involving all stakeholders' participation, alignment, and engagement. In the future, the States and regions with a higher LINAC shortage should be prioritized to improve RT access across the country. Considering the data and the initial project deadline, PER-SUS did not achieve the pre-established goals specified by the Brazilian Government. Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

A resiliência de sistemas de saúde: apontamentos para uma agenda de pesquisa para o SUS / The health systems resilience: notes for a research agenda for the SUS

RESUMO A pandemia provocada pela Covid-19 deu relevância à resiliência dos sistemas de saúde. Neste artigo, buscou-se explorar elementos que subsidiem uma agenda de pesquisa sobre resiliência para o Sistema Único de Saúde (SUS). A partir de revisão de escopo, analisou-se o desenvolvimento conceitual e metodológico da resiliência aplicada à pesquisa sobre sistemas de saúde em nível internacional e nacional, identificando quem são os grupos formuladores e o que propõem como modelos de análise. Em seguida, apresentou-se uma proposta de modelo de análise de resiliência adaptada às características do sistema de saúde brasileiro. O modelo embasou o apontamento de questões-chave a serem investigadas em pesquisas sobre a resiliência do SUS, a partir de quatro dimensões: governança e liderança, financiamento, recursos (força de trabalho, infraestrutura, medicamentos e tecnologias) e prestação de serviços. Ao final, discutem-se oportunidades e desafios para implementação de uma agenda de pesquisas de resiliência para o SUS.

ABSTRACT The COVID-19 pandemic highlighted the resilience of health systems. In this paper, we seek to explore elements to support a research agenda on resilience for the Unified Health System (SUS). First, based on a scoping review, we analyzed the conceptual and methodological development of resilience applied to health systems research both at international and national levels, identifying who the formulating groups are and what they propose as analytical frameworks. Then, we propose an analytical framework adapted for the Brazilian health system features. The framework underpinned the pointing out of critical issues to be investigated in research on SUS resilience, based on four dimensions: governance and leadership, financing, resources (workforce, infrastructure, medicines, and technologies), and service provision. Finally, we discuss opportunities and challenges for implementing a research agenda on resilience for the SUS.

Prevalências e desigualdades no acesso aos medicamentos por usuários do Sistema Único de Saúde no Brasil em 2013 e 2019 / Prevalence rates and inequalities in access to medicines by users of the Brazilian Unified National Health System in 2013 and 2019 / Prevalencias y desigualdades en el acceso a los medicamentos por parte de los usuarios del Sistema Único de Salud en Brasil en 2013 y 2019

O objetivo do estudo foi analisar e comparar a prevalência, a forma de obtenção e os fatores associados ao acesso a medicamentos entre usuários do Sistema Único de Saúde (SUS) no Brasil. Foram analisados os dados das edições 2013 e 2019 da Pesquisa Nacional de Saúde, estudo de abrangência nacional e representativo da população brasileira. Os desfechos foram: (1) a obtenção total, por meio do SUS, dos medicamentos prescritos em atendimentos em saúde realizados no próprio SUS nas duas semanas anteriores à entrevista, e (2) a obtenção total dos medicamentos independentemente da fonte. Características demográficas e socioeconômicas foram incluídas como variáveis independentes. Em 2019, observou-se que 29,7% dos entrevistados obtiveram no SUS todos os medicamentos prescritos, que 81,8% tiveram acesso total aos medicamentos quando consideradas todas as fontes de obtenção e que 56,4% pagaram algum valor pelos medicamentos. A proporção de pessoas que não obtiveram nenhum medicamento no SUS e que efetuaram algum desembolso direto aumentou entre 2013 e 2019. A probabilidade de obter todos os medicamentos no SUS foi maior entre os mais pobres, e de consegui-los, independentemente da fonte, foi maior entre os mais ricos. Dentre as pessoas que não conseguiram acesso a todos os medicamentos, aproximadamente duas em cada três indicaram como principal motivo dificuldades de obtenção encontradas em serviços financiados pelo setor público. Verificou-se ampliação do desembolso direto para compra de medicamentos no Brasil e redução de acesso pelo SUS entre usuários do sistema.

The study aimed to analyze and compare the prevalence of access to medicines and associated factors among users of the Brazilian Unified National Health System (SUS). The authors analyzed data from the 2013 and 2019 editions of the Brazilian National Health Survey, a nationwide health study, representative of the Brazilian population. The outcomes were: (1) obtaining from the SUS all the medicines prescribed during care received in the SUS itself in the two weeks prior to the interview (2) and obtaining all the medicines, regardless of the source. Demographic and socioeconomic characteristics were included as independent variables. In 2019, 29.7% of the interviewees obtained all the prescribed medicines from the SUS, 81.8% obtained all the medicines in general (considering all sources), and 56.4% paid some amount for the medicines. The proportion who did obtain any medicine from the SUS and that made some out-of-pocket payment increased from 2013 to 2019. The likelihood of obtaining all the medicines in the SUS was higher among the poorest, and that of obtaining the medicines regardless of source was higher among the wealthiest. Approximately two out of three persons that were unable to access all the medicines reported difficulties obtaining them in services funded by the public sector. There was an increase in out-of-pocket expenditure on medicines in Brazil and a reduction in access through the SUS, among users of the system.

El objetivo de este estudio fue analizar y comparar la prevalencia, la forma de obtención y los factores asociados al acceso a los medicamentos entre los usuarios del Sistema Único de Salud (SUS) en Brasil. Se analizaron los datos de las ediciones 2013 y 2019 de la Encuesta Nacional de Salud, un estudio de cobertura nacional y representativo de la población brasileña. Los resultados fueron: (1) la obtención total, a través del SUS, de los medicamentos prescritos en los servicios de salud realizados en el propio SUS en las dos semanas anteriores a la entrevista, y (2) la obtención total de los medicamentos independientemente de la fuente. Las características demográficas y socioeconómicas se incluyeron como variables independientes. En 2019 se observó que el 29,7% de los entrevistados obtuvo todos los medicamentos prescritos en el SUS, que el 81,8% tuvo acceso total a los medicamentos al considerar todas las fuentes de obtención y que el 56,4% pagó por los medicamentos. La proporción de personas que no obtuvieron ningún medicamento en el SUS y que realizaron algún gasto directo aumentó entre 2013 y 2019. Entre los pobres, la probabilidad de obtener todos los medicamentos del SUS fue mayor, y entre los más ricos también fue mayor esta obtención independientemente de la fuente. Entre las personas que no pudieron acceder a todos los medicamentos, aproximadamente dos de cada tres indicaron como razón principal las dificultades que se encuentran en los servicios financiados con fondos públicos. Hubo un aumento del gasto directo para la compra de medicamentos en Brasil y una reducción del acceso a través del SUS entre los usuarios del sistema.