Effects of Native Whey Protein and Carbohydrate Supplement on Physical Performance and Plasma Markers of Muscle Damage and Inflammation during a Simulated Rugby Sevens Tournament: A Double-Blind, Randomized, Placebo-Controlled, Crossover Study.

The importance of optimized recovery during a sport competition is undisputed. The objective of this study was to determine the effects of recovery drinks comprising either carbohydrate only, or a mix of native whey proteins and carbohydrate to maintain physical performance and minimize muscle damage during a simulated rugby sevens (rugby 7s) tournament. Twelve well-trained male rugby players participated in three simulated rugby 7s tournament days with a week's interval in between. Each tournament comprised a sequence of three simulated matches, interspersed with 2 h of recovery. Three different recovery drinks were tested: a placebo (PLA, nonenergetic chocolate-flavored drink), a carbohydrate drink (CHO, 80 g of carbohydrate) or an isoenergetic carbohydrate-protein drink (P-CHO, 20 g of Pronativ®, native whey protein and 60 g of carbohydrate). A different recovery drink, consumed after each match, was tested during each simulated tournament. Physical performance, muscle damage and muscle pain were assessed before and after each simulated tournament. Regarding physical performance, both P-CHO and CHO drinks had a positive effect on the maintenance of 50 m sprint time compared to the PLA drink (effect sizes large and moderate, respectively). Regarding muscle damage, the P-CHO supplement attenuated the creatine phosphokinase increase at POST6 compared to PLA (effect size, moderate). Finally, P-CHO and CHO drinks reduced the exercise-induced DOMS (effect size, moderate), compared to the PLA condition (effect size, large), while P-CHO only reduced pain on muscle palpation and pain when descending stairs compared to PLA 24 h post-tournament (effect size, small). This study suggests that consuming a recovery drink containing native whey proteins and carbohydrate or carbohydrate only after each match of a rugby 7s tournament may attenuate the exercise-induced increase in markers of muscle damage and maintain physical performance.

Concurrent Training Programming: The Acute Effects of Sprint Interval Exercise on the Subsequent Strength Training.

Exercise modality has been proposed to reduce the interferences between aerobic and resistance sessions during concurrent training. The aim of the study was to examine the acute effects of cycling or running sprint interval exercise on subsequent resistance training sessions. Twenty-five competitive male rugby union players were recruited. Players were tested during three conditions: CONTROL (resistance training session only), CYCLE and RUN (corresponding to a concurrent training scheme with cycling or running sprint interval exercise conducted on the morning, followed by a resistance training session). Four hours rest was proposed between the aerobic and resistance training session. Muscle performance (bar velocity during bench press and box squat, counter movement jump height) and subjective ratings (rate of perceived exertion, wellbeing) were assessed during and after aerobic or resistance training sessions. No significant difference was observed for muscle performance (vertical jump height and bar velocity). However, significant higher perceived exertion and low-value scaled subjective wellbeing were observed in RUN (7.7 ± 1.1 and 17.9 ± 4.1, respectively) as compared with the two other conditions (6.7 ± 1.5 and 21.1 ± 3.6 for CONTROL and 7.4 ± 1.1 and 20.1 ± 3.9 for CYCLE). It was concluded that the exercise modality (running or cycling) during the aerobic exercise using a sprint interval exercise did not impact the quality of the resistance session. However, subjective ratings were affected the following days. Cycling exercises might be more adequate when performing a sprint interval training session during concurrent training programs.

Chapitre 2. Le principe de dignité : un principe universel de portée limitée.

Internationally, as in many national texts, human dignity is repeatedly invoked as the cardinal reference in bioethics. In reality, this principle has particular legal characteristics linked to its dual nature of objective principle and subjective principle. However, insofar as it constitutes, in its objective dimension, an obstacle to the instrumentalization of the human being, it sometimes seems to present an incantatory and rhetorical character. In this sense, the conception of fundamental rights organized exclusively on the basis of the freedom of a self-centered individual turns out to be less protective than the principle of dignity as it is the basis of prohibitions.

Can we use GPS for assessing sprinting performance in rugby sevens? A concurrent validity and between-device reliability study.

The purpose of this study was to (1) provide data on maximal sprinting speed (MSS) and maximal acceleration (Amax) in elite rugby sevens players measured with GPS devices, (2) test the concurrent validity of the signal derived from a radar device and a commercially available 16 Hz GPS device, and (2) assess the between-device reliability of MSS and Amax of the same GPS. Fifteen elite rugby sevens players (90 ± 12 kg; 181 ± 8 cm; 26 ± 5 y) participated in the maximal sprinting test. A subset of five players participated in the concurrent validity and between-devices reliability study. A concurrent validity protocol compared the GPS units and a radar device (Stalker ATS II). The between-device reliability of the GPS signal during maximal sprint running was also assessed using 6 V2 GPS units (Sensorevery-where, Digital Simulation, Paris, France) attached to a custom-made steel sled and pushed by the five athletes who performed a combined total of 15 linear 40m sprints. CV ranged from 0.5, ±0.1 % for MSS and smoothed MSS to 6.4, ±1.1 % for Amax. TEM was trivial for MSS and smoothed MSS (0.09, ±0.01) and small for Amax and smoothed Amax (0.54, ±0.09 and 0.39, ±0.06 respectively). Mean bias ranged from -1.6, ±1.0 % to -3.0, ±1.1 % for smoothed MSS and MSS respectively. TEE were small (2.0, ±0.55 to 1.6, ±0.4 %, for MSS and smoothed MSS respectively. The main results indicate that the GPS units were highly reliable for assessing MSS and provided acceptable signal to noise ratio for measuring Amax, especially when a smoothing 0.5-s moving average is used. This 16 Hz GPS device provides sport scientists and coaches with an accurate and reliable means to monitor running performance in elite rugby sevens.

Preconditioning Strategy in Rugby-7s Players: Beneficial or Detrimental?

PURPOSE: Preconditioning strategies are considered as opportunities to optimize performance on competition day. While investigations conducted in rugby players on the effects of a morning preconditioning session already exist, additional work is warranted. The aim of this study was to monitor changes in physical and psychophysiological indicators among international Rugby-7s players following a priming exercise. METHODS: In a randomized crossover-design, fourteen under-18 international Rugby-7s players completed, at 8:00am, a preconditioning session consisting of a warm-up followed by small-sided games, accelerations and 2 x 50-m maximal sprints (Experimental) or no pre-loading session (Control). Following a 2-hour break, the players performed a set of six 30-m sprints and a Rugby-7s match. Recovery-stress state and salivary stress-markers levels were assessed before the preloading session (Pre), immediately after (Post-1), before the testing session (Post-2) and after (Post-3). RESULTS: Experimental-Control differences in performance across a repeated sprint test consisting of six 30-m sprints were very likely trivial (+0.2 ±0.7%, 3/97/1%). During the match, the total distance covered and the frequency of decelerations were possibly lower (small) in Experimental compared to Control. Differences observed in the other parameters were unclear or possibly trivial. At Post-2, the perceived recovery-stress state was improved (small difference) in Experimental compared with Control. No difference in salivary cortisol response was observed while the preconditioning session induced a higher stimulation of salivary testosterone and alpha-amylase. CONCLUSIONS: The players' ability to repeat sprints and physical activity in match-play did not improve but their psychophysiological state was positively affected after the present pre-conditioning session.

[Dignity, founding principle of law]. / La dignité, principe fondateur du droit.

The principle of dignity made a noted appearance in the legal field on the occasion of the adoption of the first texts concerning bioethics. There is in fact an obvious correlation between the need to provide a framework for certain practices and the principle of human dignity. This recognition, which can be seen in international and European law as much as in national law, is marked by certain ambiguities as to its meaning and its impact. So this principle should be subjected to a legal analysis. From this point of view, it presents three main characteristics, it is a matrix principle, which cannot be waived and it constitutes an objective right. Today, beyond its formal recognition, the effectiveness of the principle of dignity is weakened by a tendency to give prevalence to the requirement of freedom, as a subjective right. Beyond the ideological debate on this issue, it is the protection of the individual that is at stake.

ProViz: protein interaction visualization and exploration.

UNLABELLED: ProViz is a tool for the visualization of protein-protein interaction networks, developed by the IntAct European project. It provides facilities for navigating in large graphs and exploring biologically relevant features, and adopts emerging standards such as GO and PSI-MI. AVAILABILITY: ProViz is available under the GPL and may be freely downloaded. Source code and binaries are available at http://cbi.labri.fr/eng/proviz.htm CONTACT: david.sherman@labri.fr