Preparation and characterization of alloys of the Ti-15Mo-Nb system for biomedical applications.

In the development of new metallic biomaterials, the Ti-15Mo alloy has great prominence because of its excellent corrosion resistance and good combination of mechanical properties. In this study, the element niobium was added to the Ti-15Mo alloy, forming the Ti-15Mo-Nb system for the purpose of improving their properties and promoting its application as a biomaterial. These alloys are very promising to use as biomedical implants, because they integrate a new class of titanium alloys without the presence of aluminum and vanadium, which may cause cytotoxic effects. The alloys were produced by arc-melting and characterized by density, X-ray diffraction, scanning electron microscopy, microhardness, elastic modulus, corrosion, and cytotoxicity assays. The developed alloys have ß phase predominance (with bcc crystalline structure). The addition of niobium decreases the microhardness and elastic modulus, with values around 80 GPa, which is well below that of the metallic alloys used commercially for this type of application. Very low passive current densities were found for all alloys studied showing that the passive film on these alloys is highly protective. In vitro cytotoxicity tests revealed that the introduction of niobium did not cause cytotoxic effects in the studied alloys. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 639-648, 2018.

Adult-Onset Still's Disease and cytomegalovirus infection.

We present a case of a previously asymptomatic 34-year-old man that presented to the emergency department with two weeks of fever, arthralgia of the wrists and knees and sore throat. He was diagnosed with cytomegalovirus (CMV) mononucleosis. The patient remained symptomatic in the 5 following months. After an extensive workup to exclude other clinical conditions, a liver biopsy was performed and CMV hepatitis was diagnosed. He started valganciclovir therapy. Approximately one year after the initial complaints, the patient remained ill and presented clinical criteria compatible with Adult Onset Still's Disease. The patient had a marked improvement after institution of prednisolone, an effect that has been sustained during the following months.

[Kikuchi's disease. A rare cause of fever, lymphadenopathies and polyarthritis]. / Doença de Kikuchi. Uma causa rara de febre, linfadenopatias e poliartrite.

This is a case report of a 29-year-old white female patient with Kikuchi's disease, presenting fever, polyarthritis, lymph gland enlargement, anemia, leucopenia with a relative lymphocytosis, altered liver function tests and circulating immune complexes. A literature review is made with emphasis on the etiology, clinical course and pathogenesis of this illness.

[Factors involved in the survival and mortality of intensive care patients in Panama]. / Factores inherentes a la sobrevida y mortalidad de pacientes de cuidados intensivos en Panamá.

Biotechnology has been important for the management of the critical ill patients. Today the treatment is expensive and even more with complications, this work has the purpose to find out about mortality and survival and the associated factors that could promote alterations in the outcome. The authors studied 247 admissions in a six months period, their mortality and survival. We investigated the relationship between the inflammatory systemic response syndrome, the multi systemic organ failure and sepsis, with mortality and survival. We concluded that there is a high mortality related to the septic syndrome. Prevention to avoid the septic syndrome, is the best way to lower the high cost in the intensive care units.

Factores inherentes a la sobrevida y mortalidad de pacientes de cuidados intensivos en Panamá / Factors involved in the survival and mortality of intensive care patients in Panama

Biotechnology has been important for the management of the critical ill patients. Today the treatment is expensive and even more with complications, this work has the purpose to find out about mortality and survival and the associated factors that could promote alterations in the outcome. The authors studied 247 admissions in a six months period, their mortality and survival. We investigated the relationship between the inflammatory systemic response syndrome, the multi systemic organ failure and sepsis, with mortality and survival. We concluded that there is a high mortality related to the septic syndrome. Prevention to avoid the septic syndrome, is the best way to lower the high cost in the intensive care units

Causa de mortalidad en la Unidad de Cuidado Intensivo de Cirugia en La Caja de Seguro Social de Panamá / Cause of mortality in the surgery intensive care unit at the Social Security Branch of Panamá

The authors analyzed the mortality of patients admitted to the Surgical Intensive Care Unit of the Social Security Metropolitan Hospital Complex (SSMHC) in the city of Panama, from January to July 31, 1994. They determined that most of patients were males under 65 years of age and that the main cause of death was multiple trauma with shock. There was also a strong correlation between the syndrome of multiple organ failure, sepsis and death. The 17% mortality indicates an acceptable, good management of the patients admitted to the Surgical Intensive Care Unit of the SSMHC

[Cause of mortality in the surgery intensive care unit at the Social Security Branch of Panamá]. / Causa de mortalidad en la Unidad de Cuidado Intensivo de Cirugia en La Caja de Seguro Social de Panamá.

The authors analyzed the mortality of patients admitted to the Surgical Intensive Care Unit of the Social Security Metropolitan Hospital Complex (SSMHC) in the city of Panama, from January to July 31, 1994. They determined that most of patients were males under 65 years of age and that the main cause of death was multiple trauma with shock. There was also a strong correlation between the syndrome of multiple organ failure, sepsis and death. The 17% mortality indicates an acceptable, good management of the patients admitted to the Surgical Intensive Care Unit of the SSMHC.

Relapsing polychondritis and Reiter's syndrome.

We describe a case of relapsing polychondritis associated with Reiter's Syndrome in a 46-year-old white man. Relapsing polychondritis is a rare disorder of unknown etiology associated in about 30% of cases with other rheumatic disorders such as connective tissue diseases, vasculitis and exceptionally, seronegative spondyloarthritis. We found this association only once in our review of the literature.