A Bibliometric Analysis on Tuberculosis and Diabetes Mellitus 2: Visualization, Patterns, and Trends.

BACKGROUND: The convergence of type 2 diabetes mellitus (DM2) and tuberculosis (TB) may lead to increased mortality and complications, so the underlying mechanism is under investigation. Therefore, a bibliometric analysis was performed to describe the bibliometric indicators of publications evaluating the relationship between TB and DM2. METHODS: A descriptive and observational bibliometric study was conducted using the Scopus database to identify documents published from 2016-2023, for which free and controlled terms (Medical subject headings and Emtree) were used. The variables collected comprised the number of published documents, institutions, countries, authors, journals, and type of collaboration, which were exported to Excel 2016 and analyzed with SciVal. RESULTS: A total of 456 documents, 1624 authors, and 2173 citations were identified, with Medicine and Immunology-Microbiology being the subcategories with the highest and lowest number of documents (367 and 80 documents), respectively, with a strong decreasing trend correlation (R2: 0.95; P < 0.5) between the number and year of publication. While the country with the highest production was China (71 papers), the country with the highest citation was the United States (952 citations). In terms of authors, the highest production was by the American Venketaraman, and the highest impact was by the Asian Kimberly To. The institution with the highest number of papers was the Western University of Health Sciences, while Stellenbosch had the highest impact. CONCLUSION: Although the scientific productivity of DM2 and TB have reported growth rates of 158.75% and 7.3%, respectively, our results found a decreasing trend in publications associating these two diseases. The thematic evolution of the concepts in both diseases suggests that the relationship between them is not yet known, so future studies evaluating the underlying mechanisms of this comorbidity are suggested.

Web of Science-Based Scientometric Assessment of the Importance of Filtered Water in Dentistry: Spatiotemporal Dynamics, Emerging Patterns, and Collaboration.

Objective: The aim of this study was to examine the characteristics of scientific production related to the use of filtered water in the field of dentistry. Material and Methods. A quantitative and descriptive observational study was carried out with a scientometric approach. Data were collected from the Web of Science (WOS) database during the period January 1991 to December 2023. A search strategy incorporating a combination of MeSH terms, including terms and thesauri related to "filtered water" and "dentistry", was used. R Studio version 4.3.2 and CiteSpace 6.2.R7 were used for data analysis. Results: Over the 32-year study period, 227 scholarly papers from 134 different sources were reviewed. The literature in this field has shown an annual growth rate of 10.44%. During the year 2010, a steady movement in the number of publications and authors was observed, with considerable collaborative interaction. In the year 2020, a large interaction between publications and their citations was found. The "Citation Burst" graph identified three references that have experienced the largest "burst" of citations in an evaluated period. Lotka's law described the productivity of authors, finding that most authors have published only one paper, while a smaller number of authors have published two papers. Most authors contributed a small number of articles, while a few authors contributed a large amount of the existing literature. Conclusion: A comprehensive overview of the scientific production related to the use of filtered water in dentistry over a span of 32 years is provided. The results highlight the growing interdisciplinarity and international collaboration in this field. Finally, the importance of filtered water in dentistry and its growing relevance in the scientific literature are emphasized.

Periodontitis and Neuropathic Diseases: A Literature Review.

Aim: This narrative review aimed at identifying the existing scientific literature investigating periodontitis and neuropathic diseases. Materials and Methods: A search of the literature published between 2000 and 2022 was carried out in the electronic databases of Scopus and PubMed. Studies in which the eligible articles were mainly published in English were included. Descriptive correlational studies, case-control studies, comparative studies, and cohort studies were also included. The following main keywords were used: "Neuropathic diseases," "Periodontitis," "Alzheimer's disease," and "Porphyromonas gingivalis." Results: This narrative review found that cognitively impaired persons with severe periodontitis had a higher prevalence and incidence of periodontal diseases than the rest of the population. A significant positive correlation of salivary interleukin (IL)-1beta and immediate recall scores involved in cognition was also evident. It indicates that the most investigated parameter was whether there is any common link between periodontal disease and neurodegeneration. No randomized controlled clinical studies were found in the current literature review. Conclusions: Based on the literature reviewed, there is currently no strong scientific evidence to support or discourage the cause-effect relationship of periodontal diseases and neurodegenerative diseases.

Overview, Trends, and Collaboration on Immunization, Vaccination, and Immunomodulation Therapies for Periodontitis: A Scientometric Study.

AIM: To identify patterns and trends in the field of immunization, vaccination, and immunomodulation therapies for periodontitis. MATERIALS AND METHODS: Metadata were collected from the Scopus database on publications related to these topics from January 1986 to February 2024. Several types of papers were included in this study, a total of 22 publications. Data were extracted from relevant publications and loaded into SciVal for analysis that were used to identify trends and patterns in the data, including cross-country collaboration, thematic evolution, and keyword distribution. RESULTS: Mohsen Amin of Tehran University of Medical Sciences in Iran and S. Aadil Ahamed and Annie Kitty George of Saveetha Institute of Medical and Technical Sciences in India were found to be notable contributors in this field. India leads in terms of academic paper production, followed by Iran and China. The journals Expert Review of Vaccines and International Immunopharmacology have published significant papers in this field. CONCLUSIONS: According to Lotka's Law, most authors have written only one paper, reflecting the distribution of productivity in many academic and scientific fields. Collaborations were observed between Iran and Canada, Korea and New Zealand, and the United States and Belgium. This study provides useful insight into the predominant trends and patterns in the scientific literature in the field of immunization, vaccination, and immunomodulation therapies for periodontitis. CLINICAL SIGNIFICANCE: The findings of this study may help to understand the dynamics of the production on immunization, vaccination, and immunomodulation therapies could reduce the inflammation and progression of periodontitis, thus improving the patient's oral and overall health. How to cite this article: Mauricio F, Mendoza R, Silva H, et al. Overview, Trends, and Collaboration on Immunization, Vaccination, and Immunomodulation Therapies for Periodontitis: A Scientometric Study. J Contemp Dent Pract 2024;25(2):128-133.

Shear strength of metal brackets using LED lamps with different wavelengths: An in vitro comparative study.

AIM: To evaluate the shear strength of Orthocem and BracePaste polymerizable cement light-cured with light-emitting diode (LED) units with different wavelengths (Bluephase N) with their high power, low power, and soft start programs in the bonding of metal brackets. MATERIALS AND METHODS: In vitro experimental research was performed. Mini Roth 0.022 metal brackets (Roth Orthometric brackets) were used. The adhesives were placed on the metal brackets with Orthocem and BracePaste resin cement. To compare the average strengths, the analysis of variance (ANOVA) test was used (P < 0.05). RESULTS: The average shear strength was better with Bracepaste polymerizable cement compared to Orthocem cement in all its high power, low power, and soft star programs; the highest was Bracepaste with soft start of 26.52 MPa, and the lowest was Orthocem with soft start of 13.92 MPa. When evaluating the differences, it was found that these were statistically significant in all groups (P < 0.05). CONCLUSIONS: Differences were found in the shear strength of light-curing Orthocem and Bracepaste light-curing cement cured with LED units with different wavelengths in bonding metal brackets to the tooth in vitro.

Antibacterial Efficacy of Matricaria recutita Essential Oil against Porphyromonas gingivalis and Prevotella intermedia: In Vitro Study.

AIM: To evaluate in vitro the antibacterial efficacy of Matricaria recutita (chamomile) essential oil at 50 and 75% against Porphyromonas gingivalis ATCC 33277 and Prevotella intermedia ATCC 25611 at 24 and 48 hours. MATERIAL AND METHODS: The sample consisted of 80 discs and Mueller-Hinton Agar, the medium chosen for the culture. To determine the bacterial sensitivity, discs were placed in each Petri dish with concentrations of essential oil at 50 and 75%, distilled water and 0.12% chlorhexidine. Subsequently, the inhibition halos were measured in millimeters at 24 and 48 hours after culture, with the Kirby-Bauer disk diffusion method. RESULTS: In groups treated with Porphyromonas gingivalis, measurements at 24 and 48 hours yielded 22.14 ± 2.61 and 22.63 ± 2.67 mm for 0.12% chlorhexidine, 18.90 ± 0.41 and 19.22 ± 0.54 mm for 75% essential oil, and 15.55 ± 0.45 and 15.77 ± 0.46 mm for 50% essential oil, respectively. No statistically significant differences were observed among the groups (p > 0.05). CONCLUSION: No significant differences were found between the antibacterial efficacy of 0.12% chlorhexidine and 50 and 75% essential oil of Matricaria recutita on Porphyromonas gingivalis and Prevotella intermedia at 24 and 48 hours. CLINICAL SIGNIFICANCE: The study demonstrates that essential oil derived from Matricaria recutita may effectively combat bacteria associated with periodontal disease. This discovery has the potential to impact dental practice by introducing a natural treatment option. Further research is warranted to fully elucidate the clinical significance and potential applications of this finding.

Exploration and Bibliometric Mapping of Scientific Production on Quality of Life, Social Impact, and Security in Love Relationships in Patients with Dental Prostheses.

AIM: To explore and conduct a bibliometric mapping of scientific production on quality of life, social impact, and security in love relationships in patients with dental prostheses. MATERIALS AND METHODS: This study is a bibliometric, retrospective, observational analysis of scientific publications indexed in Scopus from 2017 to 2022. The search was conducted on March 8, 2023, using the MESH thesaurus and a defined search strategy. Fifty-two relevant studies were identified and exported to the SciVal program for further analysis. Various bibliometric indicators were used to analyze scientific production, including number of citations, publication, authorship, institution and collaboration, journal quartile, country of origin, h-index, CiteScore 2020, SCImago Journal Rank (SJR), Field Weighted Citation Impact (FWCI), and Source Normalized Impact per Paper (SNIP). RESULTS: Most of the articles (39) were in the highest quality quartiles (Q1 and Q2). Brazil produced a total of 15 scientific publications with a domain-weighted impact of 0.65, while Germany produced a total of 11 publications with a domain-weighted impact of 3.15. The results show that international collaboration (32.7%) and national collaboration (38.5%) are more frequent. The most influential author is Daniel Ralph Reißmann with a total of 72 publications followed by Oliver Schierz with 27 publications. German institutions (University of Hamburg, Leipzig University, and Ludwig Maximilian University of Munich) lead in scientific productivity. The Journal of Prosthetic Dentistry (Q1) has the highest number of articles (7) and a citation-to-publication ratio of 14.7. CONCLUSION: Scientific production on quality of life in patients with dental prostheses is still scarce, although its dissemination is mainly in high-impact scientific journals. CLINICAL SIGNIFICANCE: This study provided a deeper understanding of how dental prostheses affect people's lives. This can provide practitioners with valuable information to make clinical treatment decisions to improve quality of life. In addition, it can guide future studies to deepen the understanding of this topic in the clinical setting.

Global academic output on COVID-19 and Guillain-Barre Syndrome: A bibliometric analysis.

The purpose of this study was to bibliometrically analyze scientific publications on Guillain-Barré syndrome (GBS) related to COVID-19. A specialized search of the Scopus was used (December 2019 to February 2022). Collected publications were evaluated in Scival (Elsevier). The results were arranged in tables for presentation. We found 959 papers that were collected and the highest percentage of these belonged to the area of Neurology. Josef Finsterer was the author with the highest academic production, but Benedict Michael was the one with the highest impact worldwide. Although the Universidade Federal de São Paulo (Brazil) was the college with the highest scientific production, it was King's College London that reported the highest impact. Regarding the journals, the Journal of Neurology is the one with the highest worldwide production. In addition, an increase in first quartile publication and articles with national collaboration was reported. Scholarly output on COVID-19 and GBS have been increasing. Although national collaboration has the highest proportion of manuscripts, it is the international type that reported a greater impact, this would show a great interest on the part of researchers from all over the world regarding this topic.

Antibacterial Efficacy against Streptococcus mutans of Different Desensitizing Dentifrices: A Comparison In vitro Study.

AIM: To evaluate the antibacterial efficacy of desensitizing dentifrices. MATERIAL AND METHODS: An experimental, in vitro, longitudinal, analytical, and prospective study was carried out. Subsequently, the following groups were formed: Streptococcus mutans vs Vitis® Sensible. S. mutans vs Sensodyne® Repair and Protect. Also, S. mutans vs Colgate® Sensitive Pro-ReliefTM and S. mutans vs Colgate Total 12® at 100, 50, 25, and 12.5%. Each Petri dish was properly labeled with the letter corresponding to the toothpaste and was placed in the incubator for 24 hours at 37°C. A 0.12% chlorhexidine solution was used as a positive control and distilled water as a negative control. The manuscript was written following the checklist for reporting in vitro studies (CRIS) guidelines. RESULTS: It was found that when comparing the inhibition halos of the desensitizing toothpaste against S. mutans, Colgate® Sensitive Pro-ReliefTM 100% paste had the highest efficacy at 24 and 48 hours with an average of 25.2 ± 1.0 and 23.5 ± 1.1 mm, respectively. On the other way, Sensodyne paste had no efficacy at any of its concentrations 100, 50, 25, and 12.5%. Finally, it was found that there were statistically significant differences between each of the groups evaluated with a p < 0.001. CONCLUSIONS: It was concluded that mainly the 100% pure concentrations of the desensitizing pastes had antibacterial efficacy against S. mutans. However, Sensodyne® Repair and Protect paste had no effect. CLINICAL SIGNIFICANCE: This research has clinical relevance because the use of desensitizing pastes is highly frequent. Therefore, it is necessary to know if these pastes offer an efficient antibacterial effect to control the main microorganisms of the oral cavity.

Scholarly Output in Peruvian National Dentistry according to Gender Disparity: A 10-Year Bibliometric Study.

Objective: To evaluate Peruvian scientific publications in dentistry according to sex disparity (2011-2020). Methods: This was a retrospective bibliometric study. The unit of analysis was made up of Peruvian dentistry publications indexed in the Scopus database during the last 10 years. Records with metadata (410) corresponding to the period 2011-2020 were downloaded and standardized and refined by analyzing the metadata. The search strategy was developed based on the individual profiles of each Peruvian institution that has a dental school or college. It was evaluated according to the AF-ID of each institution in the Scopus database. In addition, the information provided by the Scopus SciVal tool was used. Finally, publications, impact, and collaboration indicators were used, such as total number per document, per author, average of citations, h-index, collaboration rate, number of institutions, the Source Normalized Impact per Paper indicator, the CiteScore, and the Scopus Field-Weighted Citation Impact. Results: The greatest increase was evident in 2018, with 2019 and 2020 being the maximum peak of scientific publication growth. However, sustained growth has not been evidenced in relation to the female sex. The analysis of coauthorship by the authors revealed four large clusters, of which the first three were represented by male researchers, such as Arriola-Guillen L., Mayta-Tovalino F., and Mendoza-Azpur G., and one by a female, Guerrero María E. Evaluating the national scientific publication in dentistry according to the CiteScore, it was found that most of the publications (145) from Peru were published in Q4 journals, although 90 manuscripts were published in Q1 journals. Conclusions: The Peruvian national dental publication in the last 10 years was mainly supported by male dentists, which invites us to reflect on the need to equalize opportunities so that female researchers can also reduce these gaps.

Comparison of the Microhardness of Surface Enamel Exposed to Anti-asthmatic Inhalants.

OBJECTIVE: To determine the effect of anti-asthmatic inhalers salbutamol and budesonide on the surface microhardness of bovine tooth enamel. MATERIALS AND METHODS: The study was experimental, prospective, longitudinal, and comparative. The sample consisted of permanent mandibular incisors, which were prepared in (n = 90) blocks of dental enamel of size 3 × 3 mm and 2 mm thick, separated into 6 groups of 15 specimens each in sterile bottles properly labeled and contained in artificial saliva at 37°C. Three measurements (baseline, 5 days, and 10 days) were performed after immersion to determine the microhardness using a Vickers microdurometer programmed to apply a load of 100 gm for 15 seconds. RESULTS: It was observed that the enamel surface microhardness decreased after 5 and 10 days, after being in contact with the anti-asthmatic inhalers based on salbutamol and budesonide. In addition, it was evidenced that there is a greater decrease in the superficial microhardness of the enamel when comparing the values at the beginning and after 10 days; likewise, the reduction in the microhardness of enamel exposed to budesonide was greater (120.8 kg/mm2) compared to salbutamol (112.3 kg/mm2) (p<0.001). CONCLUSION: The two anti-asthmatic inhalers studied decreased superficial enamel microhardness, with the budesonide-based inhaler having a greater erosive effect. CLINICAL SIGNIFICANCE: This research allowed us to know the values of the microhardness of the superficial enamel after being exposed to different anti-asthmatic inhalers that are indicated in daily clinical practice. Therefore, it is important to evaluate this microhardness since the use of different inhalers is very prevalent.

Bibliometric Analysis of the Current Landscape of Global Scientific Production on the Development of Vaccines against Dental Caries.

Objective: To perform a bibliometric analysis of the scientific research on the development of vaccines against dental caries. Methods: An extraction of the scientific production published on the development of vaccines against dental caries between 2011 and 2020 was carried out from the Scopus database. Microsoft Excel was used for the elaboration of tables and SciVal for the bibliometric analysis of the data, which were divided into indicators of production, impact, and collaboration. Finally, VOSviewer was used for co-occurrence analysis of keywords and collaborative networks. Results: 106 studies were retrieved from the Scopus database, which were conducted on the development of dental caries vaccines within the years 2011-2020. Wuhan University, in China, was the university with the highest scientific production on the subject, with 4 publications. Regarding the most productive journals, the first place was occupied by the Journal of Dental Research with 7 publications. Regarding the most productive journals, the first place was occupied by the Journal of Dental Research with 7 publications. The highest percentage of the documents analyzed was in quartile 1 journals and in the national collaboration pattern. Conclusion: Most of the manuscripts regarding the development of vaccines against dental caries were published in China and in Q1 quartile journals. In addition, Yan Huimin, Yang Jingyi, Zhou Dihan, Yang Yi, Li Yuhong and Fan Mingwen were found to top the list of most productive authors. The Journal of Dental Research was also identified as the most productive and cited journal.

Antibacterial Effect of Red Laser Therapy on Enterococcus faecalis Using Different Photosensitizers: An In Vitro Study.

OBJECTIVE: To assess the antibacterial effect of red laser using different photosensitizers such as methylene blue and malachite green on monoradicular premolars contaminated with E. faecalis ATCC 29212. METHODS: This was an in vitro experimental study. Monoradicular premolars (44, 45, 34, and 35) were used, which were treated with ProTaper Next. After instrument change, irrigation, disinfection, and aspiration were performed with 2 ml of 4% NaOCl with a NaviTip 30°G needle (Ultradent, South Jordan, UT, USA). Group 1: RL + MB (red laser associated with methylene blue photosensitizer), group 2: RL + MG (red laser associated with malachite green photosensitizer), and group 3: control (no treatment). The E. faecalis strain was cultured on trypticase soy agar (TSB) (Difco, Detroit, MI, USA) and incubated at 37°C for 24 h. After the incubation period, colony-forming units (CFU/ml) of each group were counted using the plate count method. The ANOVA test was used with a significance level of p < 0.05. RESULTS: Group 1 had the lowest antibacterial contamination as it averaged only 530 ± 581.3 CFU/ml, while group 2 had the highest contamination with an average of 1990 ± 542.5 CFU/ml. Comparison revealed that there were statistically significant differences between the RL + MB and RL + MG groups (p < 0.001). CONCLUSIONS: Group 1 had the best antimicrobial potential because it presented the lowest contamination in CFU/ml of E. faecalis compared to group 2 and group 3.

Scientific Production on Monkeypox in Dentistry: A Bibliometric Analysis.

AIM: To analyze the characteristics and visibility of the scientific production of monkeypox in dentistry. MATERIALS AND METHODS: A bibliometric study was carried out with the publications indexed in the Scopus database up to 22 September 2022. A search strategy was developed using Boolean operators "AND" and "OR," in addition to the MeSH term "monkeypox virus" (MPXV) in the subarea of dentistry. The bibliometric indicators were measured objectively with the SciVal program. RESULTS: Of the publications identified, 40% were indexed in first-quartile journals. India and Brazil are the countries with two published papers, while India has more views than the rest. Banaras Hindu University, Varanasi, Uttar Pradesh, India and Dr. Ram Manohar Lohia Hospital, New Delhi, India are the institutions with the highest number of citations with respect to the world average (FWCI: 2.74). The International Dental Journal has a publication on monkeypox in the field of dentistry. India is the country with the most authors (06) who have published about the study. Samaranayake Lakshman Perera is the most productive and high-impact author. CONCLUSION: In the area of dentistry, scientific production on monkeypox is still scarce; however, the publications identified are mainly in high-impact indexed journals (Q1 and Q2). It is necessary to prioritize this disease as a line of research, in addition to articulating efforts between dental teams from different institutions. CLINICAL SIGNIFICANCE: It is necessary to demonstrate the characteristics of scientific publications on monkeypox in dentistry worldwide in order to have a panoramic view of the dynamics of scientific articles in this area.

KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion.

Metastasis is the main cause of carcinoma-related death, yet we know little about how it initiates due to our inability to visualize stochastic invasion events. Classical models suggest that cells accumulate mutations that first drive formation of a primary mass, and then downregulate epithelia-specific genes to cause invasion and metastasis. Here, using transparent zebrafish epidermis to model simple epithelia, we can directly image invasion. We find that KRas-transformation, implicated in early carcinogenesis steps, directly drives cell invasion by hijacking a process epithelia normally use to promote death-cell extrusion. Cells invading by basal cell extrusion simultaneously pinch off their apical epithelial determinants, endowing new plasticity. Following invasion, cells divide, enter the bloodstream, and differentiate into stromal, neuronal-like, and other cell types. Yet, only invading KRasV12 cells deficient in p53 survive and form internal masses. Together, we demonstrate that KRas-transformation alone causes cell invasion and partial dedifferentiation, independently of mass formation.

Theory of mind, emotion recognition and emotional reactivity factors in early multiple sclerosis: Results from a South American cohort.

OBJECTIVES: To study different components of social cognition and quality of life in patients with early multiple sclerosis and low Expanded Disability Status Scale and to test the influence of cognitive performance, fatigue and neuropsychiatric symptoms on social cognition performance. METHODS: Thirty-four patients with relapsing-remitting MS, with ≤2 years of disease duration and scores ≤2 on the EDSS and 30 healthy controls underwent neuropsychological assessment with the Brief Repeatable Neuropsychological Test Battery. Components of social cognition, such as emotion recognition, theory of mind, empathy, and emotional reactivity, were assessed with the Reading the Mind in the Eyes test, the Faux Pas task, the International Affective Imagery System, and the Empathy Quotient. Anxiety, depression, fatigue and quality of life were measured. RESULTS: Patients showed significant differences in verbal memory, executive functions and social cognition, especially emotion recognition and ToM. Regarding emotional reactivity, patients showed a positive bias in the interpretation of the valence of neutral images. CONCLUSIONS: Patients with early MS showed impairments in several components of social cognition independent of cognitive performance, neuropsychiatric symptoms and fatigue. Social cognition deficits may be present in MS even in the early stages.

Histological Comparison of Post-extraction Alveolar Bone Repair Treated with Melatonin and Calcium Sulfate: An In Vivo Study in Cavia porcellus.

AIM AND OBJECTIVE: To histologically compare alveolar bone repair after tooth extraction treated with melatonin and calcium sulfate in an in vivo experimental study in guinea pigs (Cavia porcellus). MATERIALS AND METHODS: The study was of longitudinal, prospective, and experimental design in an animal bio-model. A total of 24 male guinea pigs were included, weighing from 700 to 900 g and separated into two experimental groups (melatonin and calcium sulfate) for three periods (15, 30, and 45 days) at 15-day intervals after surgery. The guinea pigs were randomly included into groups for the time evaluated. RESULTS: In relation to bone repair cells using calcium sulfate, the presence of osteoblasts at 15, 30, and 45 days was 39.0 ± 63, 55.3 ± 6.0, respectively, with 61.3 ± 10.0 cells per field. Regarding bone repair cells using melatonin, the presence of osteoblasts at 15, 30, and 45 days was 25.0 ± 3.7, 49.3 ± 1.5, respectively, with 53.6 ± 5.6 cells per field. CONCLUSION: Both melatonin and calcium sulfate were found to be useful in bone repair at a histological and clinical level, although they present certain nonsignificant, albeit marked advantages in the bone repair process when compared with the control socket at the histological level. CLINICAL SIGNIFICANCE: This research allows us to know the usefulness of these easily accessible chemicals for the generation of bone repair.

Effects of Different Light-curing Modes on the Compressive Strengths of Nanohybrid Resin-based Composites: A Comparative In Vitro Study.

OBJECTIVE: To evaluate the effects of polymerization conducted by using LED lamps of different wavelengths (polywave and monowave) on the compressive strengths of nanohybrid composite resins Filtek™ Bulk Fill - 3M and 3M™ Filtek™ Z350 XT. MATERIALS AND METHODS: The study was prospective, experimental in vitro, and comparative. The sample consisted of nanohybrid composite resins. The sample size (n) was 100 specimens, divided into 10 groups. CRIS (Checklist for Reporting In-vitro Studies) Guidelines were used for writing this article. RESULTS: There were statistically significant differences between all groups with P < 0.001. Group 2 (nanohybrid composite resin blocks 3M™ Filtek™ Z350 XT with Monowave LED lamps) showed the highest compressive strength of 238.36±34.69N; CI (213.55-263.18) N. This was followed by Group 4 (nanohybrid composite resin blocks 3M™ Filtek™ Z350 XT with Poliwave LED lamps, High Power) and Group 6 (nanohybrid composite resin blocks 3M™ Filtek™ Z350 XT with Poliwave LED lamps, Soft Star), with compressive strengths of 222.33 ± 53.09N, and 209.21 ± 22.52N, respectively. CONCLUSIONS: Significant differences were found between the compressive strengths of 3M™ Filtek™ Z350 XT and Filtek™ Bulk Fill - 3M resins, and that of resins photopolymerized with monowave and polywave LED lamps and halogen light. Thus, the types of light and lamp directly influence the compressive strengths of the composite resins.

Management of Peri-implant Mucositis of Multiple Osseointegrated Implants Using a Modified Free Gingival Graft "Punch Technique" in the Total Edentulous Area: A Case Report.

The purpose of this case report was to describe a technique to modify the free gingival graft by perforations within the graft to guarantee a horizontal increase in the keratinized mucosa in the anteroinferior sector of a total edentulous mandible after osseointegration of previously placed dental implants in a hybrid prosthesis protocol. A 71-year-old male underwent free modified gingival graft surgery with perforations at the level of each implant. At 3 months, the mucosa appeared to be healthy and keratinized, especially at a horizontal level around the implants previously diagnosed with mucositis, providing the patient with satisfactory results. Finally, the hybrid prosthesis was cleaned and polished due to the presentation of a hard plate at the level of the abutments. Within the limitations of this case report, further research is needed to evaluate the long-term efficacy of this modification to the free gingival graft.

Comparison of the Antifungal Efficacy of Four Concentrations of Minthostachys mollis (Muña) Essential Oil against Candida albicans: An In Vitro Study.

AIM AND OBJECTIVE: This paper aims to compare the antifungal efficacy of four concentrations of Minthostachys mollis essential oil (MEO) against Candida albicans ATCC 10231. MATERIALS AND METHODS: This study was conducted in vitro. Ten kilograms of M. mollis (Muña) were collected in the city of Tarma, Peru. The plant was then dried in the shade at room temperature (21°C), and the essential oil was obtained through distillation. C. albicans ATCC 10231 was cultured at a MacFarland scale of 0.5, which corresponds to a concentration of 3 × 108 CFU/mL. Each plate was filled with one of the four MEO concentrations (25, 50, 75, or 100%), dimethyl sulfoxide (negative control), or fluconazole (positive control), a known antifungal agent. After incubation, each plate was examined using the Kirby-Bauer method. RESULTS: Compared to MEO 25%, MEO 50%, and MEO 75%, MEO 100% had the highest antifungal efficacy at 24, 48, and 72 hours of evaluation, with an average of 18.9 ± 0.7, 18.2 ± 0.7, and 17.0 ± 0.4 mm, respectively. However, fluconazole had higher efficacy (27.9 ± 0.5, 27.5 ± 0.5, and 23.7 ± 0.7 mm, respectively). Post hoc analysis showed that there were significant differences between all concentrations of the MEO groups and their respective positive and negative control groups (p <0.001). CONCLUSION: Among the MEO groups, the pure concentration (MEO 100%) had the highest antifungal efficacy. However, fluconazole presented greater efficacy, and the differences were statistically significant. CLINICAL SIGNIFICANCE: This research allowed to know the efficacy of this natural resource against one of the most prevalent fungi in the oral cavity. Therefore, a line of research could be opened to deepen its potential benefits for oral health.