1.
Org Lett
; 18(19): 5142-5145, 2016 10 07.
Article
in English
| MEDLINE
| ID: mdl-27676586
ABSTRACT
A photochemical method for the direct synthesis of 1H-pyrazoles from pyridazine N-oxides was developed. This chemistry features a regioselective approach to nonsymmetrically substituted pyridazine N-oxides. Herein, we highlight the first strategic use of photoinduced ring-opening reactions of 1,2-diazine N-oxides for the preparative synthesis of nitrogen heterocycles.
2.
Chem Commun (Camb)
; 51(25): 5287-9, 2015 Mar 28.
Article
in English
| MEDLINE
| ID: mdl-25558484
ABSTRACT
The conversion of readily available silylalkynes, iodobenzene diacetate, and azide anions was utilized to form and react cyanocarbenes. A copper(II)-catalyzed reaction was found to react in a different manner. Both of these methods benefit from the formation and in situ reaction of hypervalent iodonium alkynyl triflates in O-H insertion reactions.