ABSTRACT
La afección renal es infrecuente en la esclerosis sistémica, a diferencia de otras colagenosis. La aparición de síndrome nefrótico se ha relacionado con el uso de fármacos, especialmente la D-penicilamina, o raramente como manifestación de amiloidosis secundaria, bastante infrecuente en la esclerosis sistémica. Presentamos un caso de síndrome nefrótico en una paciente con esclerosis sistémica, producido por una glomerulonefritis membranosa, descrito de forma excepcional en la literatura (AU)
The renal affectation is infrequent in scleroderma, unlike other collagen diseases. The appearance of nephrotic syndrome has been related to the drug use, specially the D-penicilamine, or rarely as a manifestation of secondary amilodosis, quite infrequent in scleroderma. We report a case of nephrotic syndrome in a patient with systemic scleroderma, produced by a membranous glomerulonephritis, exceptionally described in literature (AU)
Subject(s)
Humans , Female , Middle Aged , Nephrotic Syndrome/complications , Scleroderma, Diffuse/complications , Glomerulonephritis, Membranous/complications , Enkephalin, D-Penicillamine (2,5)-/adverse effects , Amyloidosis/complicationsABSTRACT
The renal affectation is infrequent in scleroderma, unlike other collagen diseases. The appearance of nephrotic syndrome has been related to the drug use, specially the D-penicilamine, or rarely as a manifestation of secondary amilodosis, quite infrequent in scleroderma. We report a case of nephrotic syndrome in a patient with systemic scleroderma, produced by a membranous glomerulonephritis, exceptionally described in literature.