A Practical Approach for Ischemic Preconditioning Intervention in Sports: A Pilot Study for Cuff Thigh Occlusion Pressure Estimation Based on Systolic Blood Pressure.

For the ischemic preconditioning (IPC) intervention, the accuracy of the protocol is paramount for mediating its possible ergogenic effects. However, the lack of standardization and widespread use of arbitrary cuff pressures (ranging from 130 to >300 mmHg) have been predominantly observed, potentially affecting the results and compromising the reproducibility of findings. Thus, the purpose of this study was to determine an appropriate cuff pressure during IPC. Seventeen healthy male participants were enrolled in the study. Anthropometric measurements were initially conducted, followed by systolic and diastolic blood pressure measurements. Subsequently, we determined the individual thigh occlusion pressure (TOP) for the right leg using a hand-held Doppler device. Based on these findings, we developed an estimation equation for TOP, considering the current brachial systolic blood pressure (SBP) values. We then conducted a retrospective analysis of its capacity to mediate occlusion. We observed the ability to estimate TOP using the equation (p = 0.01; ES: 0.86), presenting ~6% superiority in absolute values for occlusion compared to direct measurement (TOP equation: 169.9 ± 9.1; TOP direct measured: 161.2 ± 11.1). However, TOP estimation was insufficient to produce complete occlusion in two out of 17 subjects (11.8%). In conclusion, the estimation of TOP incorporating SBP values may offer a valid and practical means for cuff administration during IPC protocols with potential to minimize adverse effects and maximize its positive effects.

Unveiling Bias: Examining the Influence of Positive Results on Ergogenic Aids in Published Sports Science Studies.

We investigated the potential for publication bias in the field of sports science regarding studies on ergogenic aids and their effects on exercise performance. We found evidence to suggest that journals tend to prioritize studies with positive results (76%) while neglecting those with negative outcomes (2.7%). Worryingly, this could lead to a discrepancy between reported conclusions and actual study outcomes. We also identified inconsistencies between reported outcomes and actual performance variable outcomes. Taken together, these data highlight the need for future research to reduce bias and encourage the publication of studies with both positive and negative results to improve the reliability of scientific evidence in this field.

Use of ergogenic aids among Brazilian athletes: a cross-sectional study exploring competitive level, sex and sports.

Was investigated ergogenic aids (EAs) used by Brazilian athletes and their association with performance, sex, sports classification, and modality. It identified the main purposes of EAs and their prescription. Methods: 239 athletes of 15 modalities, ranging from regional to international level, answered a survey online. Results: Highly competitive athletes consumed nutritional and mechanical aids more (OR = 1.96 CI 95% [1.28-2.9]; OR = 1.79 CI 95% [1.29-2.47]), while the use of psychological EAs decreased [OR = 1.66 95% CI (1.18-2.94); p = 0.001]. Male athletes [OR = 1.44 CI 95% (1.11-2.88)] and individual sports practitioners [OR = 1.78 CI 95% (1.02-3.11)] used nutritional aids more. Triathlon athletes had higher nutritional EA use, while soccer athletes had lower. Combat sports athletes had higher pharmacological EA use. Conclusion: Athletes use nutritional and pharmacological aids more to improve performance and gain lean body mass. Mechanical aids were used for recovery and psychological aids for motivation. Self-prescription is common, especially for pharmacological aids.

Attenuation of Neuromuscular Fatigue by Ischemic Preconditioning with Moderate Cuff Pressure is Not Related to Muscle Oxygen Saturation in Men.

Ischemic preconditioning (IPC) has been an excellent strategy for enhancing sports performance recovery, although there is still no consensus on the ideal protocol. Thus, this study aimed to evaluate the effects of IPC with different cuff pressures (low pressure, medium pressure, and high pressure) on the attenuation of neuromuscular fatigue after an isometric test protocol. And to verify whether this improvement was related to muscle oxygen saturation during the test protocol. Thirty males (18-35 years old) with experience in resistance training were allocated to three different groups: low pressure (20 mmHg), medium pressure (100 mmHg), and high pressure (190 mmHg). The individual occlusion pressure of each participant was identified using ultrasound. Each participant performed two test protocols (8 maximal isometric contractions lasting 20-s with a 10-s rest interval) in an extension chair; after the first test protocol, the participant received the IPC intervention with a low, medium, or high cuff pressure or received the noncuff intervention (randomized order). Only the medium-pressure group showed a smaller decrease in mean force change compared to the no-cuff condition (-4.40% vs. -13.10%, p=0.01, respectively), and the low- and high-pressure groups did not exhibit significant pressure differences (IPC vs. noncuff: -8.40% vs. -13.10%, p=0.11 and -9.10% vs. -14.70%, p=0.12, respectively). Muscle oxygen saturation across test protocols showed no significant differences in all IPC conditions (p>0.05). Although, IPC with medium pressure was effective at optimizing the recovery of neuromuscular performance, this improvement is not related to an increase in muscle oxygen saturation during exercise.

Mechanical demands and pacing profile adopted by elite mountain bikers during different cross-country events / Demandas mecânicas e perfil de ritmo adotado por ciclistas de montanha de elite durante diferentes eventos do cross-country

ABSTRACT Different competitive environments appears to affect the physical demands during the sports competitions. Thus, the aim of this study was to report the mechanical demand and pacing behaviour of twelve male elite mountain bikers on cross-country short track (XCC) and cross-country Olympic (XCO). During both competition, total race time, speed, power output (PO) and cadence (CA) were recorded. As the race time in the XCC is shorter (21.0 ± 0.5 vs 84.0 ± 3.0 min; p<0.01), the average speed (26.6 ± 0.6 vs 17.8 ± 0.6 km/h; p<0.01), PO (365.0 ± 26.7 vs 301.0 ± 26.2 watts; p<0.01) and CA (81.2 ± 4.7 vs 77.4 ± 4.3 rev∙min−1; p=0.01) were higher than the XCO. While a variable pacing was adopted during XCC, a positive profile was adopted in XCO. In addition, athletes adopted a more conservative starting pace during XCC (below average race speed) but a faster start during XCO (above average race speed). These findings demonstrated that mechanical parameters and pacing profile adopted by cyclists are different between XCC and XCO. Therefore, mountain bikers and coaches must develop specific strategy and training methods in order to obtain success in each competition.

RESUMO Diferentes ambientes competitivos parecem afetar as demandas físicas durante as competições esportivas. Assim, o objetivo deste estudo foi reportar as demandas mecânicas e o comportamento do pacing de doze homens ciclistas de montanha da categoria elite durante o cross-country de pista curta (XCC) e o cross-country Olímpico (XCO). Durante ambas as competições, o tempo total de corrida, velocidade, potência (PO) e cadência (CA) foram gravados. Como o tempo de prova do XCC é menor (21,0±0,5 vs 84,0±3,0 min; p<0,01), a velocidade média (26,6±0,6 vs 17,8±0,6 km/h; p<0,01), PO (365,0±26,7 vs 301,0±26,2 watts; p<0,01) e CA (81,2±4,7 vs 77,4±4,3 rev∙min−1; p=0,01) foram maiores que no XCO. Enquanto um ritmo variável foi adotado no XCC, um perfil positivo foi adotado no XCO. Além disso, os atletas adotaram um ritmo inicial mais conservador durante o XCC (abaixo da velocidade média da prova), mas um início mais rápido durante o XCO (velocidade acima da média da prova). Esses achados demonstraram que os parâmetros mecânicos e o ritmo adotados pelos ciclistas são diferentes entre o XCC e XCO. Portanto, ciclistas e treinadores devem desenvolver estratégias e métodos de treinamento específicos para obter sucesso em cada competição.

Local muscle oxygenation during different cuff-pressures intervention: a punctual near-infrared spectroscopy measurement

Abstract Aim: To verify the response of tissue saturation index (TSI) during ischemia-reperfusion (IR) interventions with different cuff-pressures. Methods: Twenty-nine healthy men experienced in resistance training were recruited. Each one has undergone a control condition (no cuff) and one of the three IR interventions: 1) 190 mmHg (CP-190, 22.7 ± 3.0 years; 176.6 ± 3.9 cm; 77.3 ± 9.5 kg; 2) 100 mmHg (CP-100, 22.9 ± 6.3 years; 180.5 ± 4.0 cm; 85.2 ± 14.1 kg) and 3) 20 mmHg (CP-20, 20.3 ± 2.4 years; 171.8 ± 5.2 cm; 72.4 ± 6.0 kg). Cuffs were placed on the proximal region of the thighs. IR interventions consisted of three cycles of 2-min occlusion-reperfusion. TSI was measured using near-infrared spectroscopy (NIRS), positioned on the middle portion of the vastus lateralis of the dominant leg. The oxygenation was measured at the control conditions (no cuff) and during cuff interventions. Results: While TSI values of CP-20 did not change compared to control (p > 0.05), the TSI in CP-190 was lower in the ischemia (p < 0.05), and CP-100 was lower in the second and third ischemia (p < 0.05). However, the TSI value increased during reperfusion but did not return to control levels (p < 0.05). Conclusion: TSI of the CP-190 significantly decreased during ischemia. However, these values increased by about 16% in the reperfusion period. Thus, our results show that the RI intervention may have caused an increase in metabolic demand, as even with the release of blood flow, the TSI values were below those of the other interventions.

Is Social Media Spreading Misinformation on Exercise and Health in Brazil?

Instagram (IG) reaches millions of people, sharing personal content and all kinds of information, including those related to exercise and health. However, the scientific quality of the posted information is questionable. Thus, this study aimed to analyze whether exercise and health information posted by popular Brazilian IG influencers has technical-scientific accuracy. A personal IG account was created to identify Brazilian IG profiles. The inclusion criteria of the accounts were: (1) having 50% of all the shared posts related to topics about exercise and health, such as nutrition, health and wellness, medicine, or physical fitness; and (2) having over 100,000 followers. Qualitative analysis revealed a low quality percentage (38.79 ± 25.43%) for all analyzed posts. Out of all the posts, only 13 (~2.7%) cited a reference endorsing the information. Moreover, the higher quality-ratio score of the posts was not directly associated with the higher educational qualification of the influencers (r = 0.313; p = 0.076). Nevertheless, the number of followers was inversely correlated with the educational qualification of the influencers (r = -0.450; p = 0.009), but not with the quality-ratio score of the posts (r = -0.178 p = 0.322). We conclude that prominent Brazilian IG influencers disseminate low-quality information about exercise and health, contributing to the wide-spreading of misinformation to millions of followers.

Ischemia-Reperfusion Intervention: From Enhancements in Exercise Performance to Accelerated Performance Recovery-A Systematic Review and Meta-Analysis.

It has been demonstrated that brief cycles of ischemia followed by reperfusion (IR) applied before exercise can improve performance and, IR intervention, applied immediately after exercise (post-exercise ischemic conditioning-PEIC) exerts a potential ergogenic effect to accelerate recovery. Thus, the purpose of this systematic review with meta-analysis was to identify the effects of PEIC on exercise performance, recovery and the responses of associated physiological parameters, such as creatine kinase, perceived recovery and muscle soreness, over 24 h after its application. From 3281 studies, six involving 106 subjects fulfilled the inclusion criteria. Compared to sham (cuff administration with low pressure) and control interventions (no cuff administration), PEIC led to faster performance recovery (p = 0.004; ES = -0.49) and lower increase in creatine kinase (p < 0.001; effect size (ES) = -0.74) and muscle soreness (p < 0.001; ES = -0.88) over 24 h. The effectiveness of this intervention is more pronounced in subjects with low/moderate fitness level and at least a total time of 10 min of ischemia (e.g., two cycles of 5 min) is necessary to promote positive effects.

Ischemic preconditioning improves performance and accelerates the heart rate recovery.

BACKGROUND: Previous studies have assessed the effects of ischemic preconditioning (IPC) on exercise performance and physiological variables, such as lactate and muscle deoxygenation. In this study, we verified the IPC effects on performance and heart rate during and immediately after a maximal incremental cycling test (ICT). METHODS: Eighteen recreationally trained cyclists (28±4 years) were allocated to one of three groups: IPC, SHAM and Control. After the first visit to familiarization, cyclists attended the laboratory on two separate occasions to perform an ICT: in the 1st visit they performed the reference test (baseline), and in 2nd the test ischemic preconditioning (2 cycles of 5-min occlusion [at 50 mm Hg above systolic arterial pressure]/ 5-min reperfusion), SHAM (identical to ischemic preconditioning, but at 20 mm Hg) or control (no occlusion) interventions (post intervention). During the ICT, heart rate, power output and perceived exertion were measured and the heart rate was monitored throughout the recovery. RESULTS: Only ischemic preconditioning group improved performance time by 4.9±4.0% and decreased heart rate at submaximal point during ICT, of 170±8 to 166±8 bpm (P<0.05). Also, IPC promoted faster heart rate recovery, mainly on first minute (from 151±9 to 145±8 bpm; P<0.05), compared to baseline. No differences for other parameters were found. CONCLUSIONS: Two cycles of five minutes of ischemia were relevant to produce positive effects on performance and alter the heart rate during and soon after ICT.

The relative peak power output of amateur mountain bikers is inversely correlated with body fat but not with fat-free mass

Abstract Aims: To evaluate whether body mass (BM) and body composition may influence mountain bike cycling performance. Methods: Forty male amateur mountain bikers attended the laboratory on two non-consecutive days. At the first visit, anthropometric measures (height, BM, body fat [BF], fat-free mass [FFM] and body mass index [BMI]) and familiarization to incremental cycling test were performed. On the second visit, cyclists performed again the incremental cycling test to measure peak power output (PPO), peak power output relative to BM (PPO-BM), and time to exhaustion (TE), which were posteriorly correlated with BM and anthropometric measures. Results: A low and moderate significant correlation were observed between TE and BM (p<0.01; r=0.40) and FFM (p<0.01; r=0.56). Moderate significant correlation was found between PPO and BM (p<0.01; r=0.45), BMI (p=0.03; r=0.35) and strong with FFM (p<0.01; r=0.59). Also, PPO-BM significantly correlated with BM (p=0.04; r=-0.31), BMI (p=0.02; r=-0.35) and BF (p<0.01; r=-0.55). No other significant correlations were observed. Conclusion: Considering PPO-BM as mainly performance variable, BM and BF can be a determining factor in mountain biking performance but FFM did not.

Combined effects of exercise training and high doses of anabolic steroids on cardiac autonomic modulation and ventricular repolarization properties in rats.

Several studies have reported that high doses of synthetic anabolic androgenic steroids (AAS) can have serious negative effects on health, including the cardiovascular system. The aim of this study was to evaluate the combined effects of AAS and exercise training on ventricular repolarization and cardiac autonomic modulation in rats. Male Wistar rats were allocated into 4 groups: sedentary rats treated with vehicle, sedentary rats treated with nandrolone decanoate, swimming-trained rats treated with vehicle, and swimming-trained rats treated with nandrolone decanoate. Ventricular repolarization was evaluated by electrocardiographic analysis of QT interval and QT dispersion. Cardiac autonomic modulation was assessed by heart rate variability. Our results show that AAS increased QT interval and QT dispersion in sedentary rats treated with nandrolone decanoate as compared to sedentary rats treated with vehicle, indicating AAS-induced ventricular repolarization abnormalities. When rats treated with nandrolone decanoate were subjected to concomitant exercise training, ventricular repolarization was normalized. On the other hand, AAS-induced reduction in cardiac parasympathetic modulation was not prevented by exercise training. In conclusion, AAS produced cardiac autonomic dysfunction and ventricular repolarization disturbances in rats. Combining an exercise training protocol during the AAS treatment attenuated the ventricular repolarization abnormalities and did not prevent cardiac autonomic dysfunction.