ABSTRACT
Rendu-Osler-Weber Syndrome also known as Hereditary Hemorrhagic Telangiectasia is a rare systemic fibrovascular dysplasia, with dominant autosomal inheritance. It is characterized by recurrent epistaxis, mucocutaneous telangiectasia, visceral arteriovenous malformation and positive family history. There may be hematologic, neurologic, dermatologic and gastrointestinal complications. Therapy is supportive and aimed at preventing complications. In this article we report a case of Rendu-Osler-Weber in a 64 year-old man, with history of mucocutaneous telangiectasia since the third decade of life, recurrent epistaxis, positive family history and vascular ectasia in the gastrointestinal tract.
Subject(s)
Telangiectasia, Hereditary Hemorrhagic/pathology , Tongue Diseases/pathology , Endothelial Cells/pathology , Humans , Male , Middle Aged , Syndrome , Telangiectasia, Hereditary Hemorrhagic/complicationsABSTRACT
Rendu-Osler-Weber Syndrome also known as Hereditary Hemorrhagic Telangiectasia is a rare systemic fibrovascular dysplasia, with dominant autosomal inheritance. It is characterized by recurrent epistaxis, mucocutaneous telangiectasia, visceral arteriovenous malformation and positive family history. There may be hematologic, neurologic, dermatologic and gastrointestinal complications. Therapy is supportive and aimed at preventing complications. In this article we report a case of Rendu-Osler-Weber in a 64 year-old man, with history of mucocutaneous telangiectasia since the third decade of life, recurrent epistaxis, positive family history and vascular ectasia in the gastrointestinal tract.
Subject(s)
Humans , Male , Middle Aged , Telangiectasia, Hereditary Hemorrhagic/pathology , Tongue Diseases/pathology , Syndrome , Telangiectasia, Hereditary Hemorrhagic/complications , Endothelial Cells/pathologyABSTRACT
Epidermodysplasia Verruciformis is a genodermatosis characterized by susceptibility to infection by specific HPV types (HPV 3/10 and beta-HPVs). It is considered to be the first model in human carcinogenesis induced by HPV. In this report we present a rare case of Epidermodysplasia Verruciformis associated with vertical transmission of HIV. Although most patients with HIV present infections by HPV virus, the frequency of Epidermodysplasia Verruciformis is no greater in patients with HIV because in EV there is a deficiency of specific cellular immunity to infection by some types of HPV, called HPV-related Epidermodysplasia Verruciformis.
Subject(s)
Epidermodysplasia Verruciformis/pathology , HIV Infections/complications , Epidermodysplasia Verruciformis/etiology , Humans , Male , Skin/pathology , Young AdultABSTRACT
Epidermodysplasia Verruciformis is a genodermatosis characterized by susceptibility to infection by specific HPV types (HPV 3/10 and beta-HPVs). It is considered to be the first model in human carcinogenesis induced by HPV. In this report we present a rare case of Epidermodysplasia Verruciformis associated with vertical transmission of HIV. Although most patients with HIV present infections by HPV virus, the frequency of Epidermodysplasia Verruciformis is no greater in patients with HIV because in EV there is a deficiency of specific cellular immunity to infection by some types of HPV, called HPV-related Epidermodysplasia Verruciformis.
A Epidermodisplasia Verruciforme é uma genodermatose que se caracteriza pela susceptibilidade à infecção por tipos específicos de HPV (HPVs 3 e 10 e os beta-HPVs) e é considerada o primeiro modelo no homem de carcinogênese induzida pelo HPV. Neste artigo apresenta-se um caso raro de Epidermodisplasia Verruciforme em um paciente com HIV desde o nascimento. Apesar dos doentes com HIV apresentarem mais infecções pelos vírus HPVs, existem poucos relatos na literatura de Epidermodisplasia Verruciforme no doente com HIV. Isso se explica, pois a Epidermodisplasia Verruciforme é consequência de uma deficiência celular específica à infecção por alguns tipos distintos de HPVs, ditos HPVs relacionados a Epidermodisplasia Verruciforme.
Subject(s)
Humans , Male , Young Adult , Epidermodysplasia Verruciformis/pathology , HIV Infections/complications , Epidermodysplasia Verruciformis/etiology , Skin/pathologyABSTRACT
As cicatrizes de acne são comuns,mas de difícil tratamento. Existem várias técnicas utilizando lasers para sua correção, sendo os fracionados de CO2 os mais usados atualmente. Entretanto, para se obter resultados significativos, o procedimento pode tornar-se muito agressivo. Propõe-se nova técnica de aplicação de laser de CO2 fracionado exclusivamente sobre as cicatrizes de acne, denominada técnica de Croll, em analogia à técnica de Cross. O objetivo é otimizar os resultados e minimizar os efeitos colaterais. Nesse trabalho relatamos 15 casos bem-sucedidos com utilização da técnica de Croll na correção de cicatrizes de acne.
Acne scars are a common however difficult to treat condition.There are a number of laser-based techniques for their correction; fractional CO2 lasers are currently the most frequently used. In order to obtain good results, interventions can, however, become considerably aggressive.Therefore, we propose a new fractional CO2 laser technique, performed only on acne scars.The objective is to optimize results with minimal side-effects.We have named it the CROLL Technique in an analogy to the CROSS technique. We report 15 cases that were successfully treated using this technique.
