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1.
Proc Int Astron Union ; 16(Suppl 362): 184-189, 2023 Jan 23.
Article in English | MEDLINE | ID: mdl-36923908

ABSTRACT

The hot accretion flow around Kerr black holes is strongly magnetized. Magnetic field loops sustained by a surrounding accretion disk can close within the event horizon. We performed particle-in-cell simulations in Kerr metric to capture the dynamics of the electromagnetic field and of the ambient collisionless plasma in this coupled configuration. We find that a hybrid magnetic topology develops with a closed magnetosphere co-existing with open field lines threading the horizon reminiscent of the Blandford-Znajek solution. Further in the disk, highly inclined open magnetic field lines can launch a magnetically-driven wind. While the plasma is essentially force-free, a current sheet forms above the disk where magnetic reconnection produces macroscopic plasmoids and accelerates particles up to relativistic Lorentz factors. A highly dynamic Y-point forms on the furthest closed magnetic field line, with episodic reconnection events responsible for transient synchrotron emission and coronal heating.

2.
Science ; 369(6510): 1497-1500, 2020 09 18.
Article in English | MEDLINE | ID: mdl-32943524

ABSTRACT

Binary interactions dominate the evolution of massive stars, but their role is less clear for low- and intermediate-mass stars. The evolution of a spherical wind from an asymptotic giant branch (AGB) star into a nonspherical planetary nebula (PN) could be due to binary interactions. We observed a sample of AGB stars with the Atacama Large Millimeter/submillimeter Array (ALMA) and found that their winds exhibit distinct nonspherical geometries with morphological similarities to planetary nebulae (PNe). We infer that the same physics shapes both AGB winds and PNe; additionally, the morphology and AGB mass-loss rate are correlated. These characteristics can be explained by binary interaction. We propose an evolutionary scenario for AGB morphologies that is consistent with observed phenomena in AGB stars and PNe.

3.
Am J Hum Genet ; 62(6): 1416-24, 1998 Jun.
Article in English | MEDLINE | ID: mdl-9585607

ABSTRACT

There is genetic predisposition associated with >=10% of all cancer of the prostate (CaP). By means of a genomewide search on a selection of 47 French and German families, parametric and nonparametric linkage (NPL) analysis allowed identification of a locus, on chromosome 1q42.2-43, carrying a putative predisposing gene for CaP (PCaP). The primary localization was confirmed with several markers, by use of three different genetic models. We obtained a maximum two-point LOD score of 2.7 with marker D1S2785. Multipoint parametric and NPL analysis yielded maximum HLOD and NPL scores of 2.2 and 3.1, respectively, with an associated P value of . 001. Homogeneity analysis with multipoint LOD scores gave an estimate of the proportion of families with linkage to this locus of 50%, with a likelihood ratio of 157/1 in favor of heterogeneity. Furthermore, the 9/47 families with early-onset CaP at age <60 years gave multipoint LOD and NPL scores of 3.31 and 3.32, respectively, with P = .001.


Subject(s)
Chromosomes, Human, Pair 1 , Prostatic Neoplasms/genetics , Age of Onset , Chromosome Mapping , Genetic Heterogeneity , Genetic Linkage , Genetic Predisposition to Disease , Genotype , Humans , Lod Score , Male , Microsatellite Repeats
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