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Study of the 111In-DTPA complex by the electromigration method.
Ivanov, P I; Bontchev, G D; Bozhikov, G A; Filossofov, D V; Maslov, O D; Milanov, M V; Dmitriev, S N.
Appl Radiat Isot ; 58(1): 1-4, 2003 Jan.
Article in English | MEDLINE | ID: mdl-12485655

ABSTRACT

The electrophoretic behavior of the 111In-DTPA radiopharmaceutical has been investigated. The stability constant, diffusion coefficient and effective charge of the complex as well as the temperature dependence of the electrophoretic mobility were determined. No-carrier-added 111In with high specific activity was used in the electrophoretic experiments in ultramicroconcentrations (10(-9)M).


Subject(s)
Indium Radioisotopes/chemistry , Pentetic Acid/analogs & derivatives , Radiopharmaceuticals/chemistry , Data Interpretation, Statistical , Diffusion , Drug Stability , Electrophoresis/methods , Hydrogen-Ion Concentration , Osmolar Concentration , Pentetic Acid/chemistry , Statistical Distributions , Temperature , Time Factors
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