Subject(s)
17-Hydroxysteroid Dehydrogenases/biosynthesis , Cell Proliferation/physiology , Liver Neoplasms/metabolism , Peroxisomal Multifunctional Protein-2/biosynthesis , 17-Hydroxysteroid Dehydrogenases/genetics , Animals , Gene Expression , Inflammation/genetics , Inflammation/metabolism , Liver Neoplasms/genetics , Peroxisomal Multifunctional Protein-2/genetics , RatsABSTRACT
Yttrium and aluminium complexes of two dithiodiolate ligands that feature different bridges (CF3)2C(OH)CH2SRSCH2C(OH)(CF3)2 (L(1)-H2, R = CH2CH2 and L(2)-H2, R = C6H4) were synthesized in good yields by reacting tris(silylamide)yttrium or trimethylaluminium with one equivalent of the proligand. All complexes were characterized by NMR and elemental analysis, and single-crystal X-ray structural analysis was also performed for one of the yttrium complexes. The catalytic activities of the four complexes in the ring-opening polymerization of ε-caprolactone and rac-lactide have been investigated. Furthermore, DOSY experiment and DFT calculations have been carried out to determine the structure of the isopropoxo derivative of the complex L(2)Y amide.