Subject(s)
Adenoma/pathology , Hair Follicle/pathology , Skin Neoplasms/pathology , Adenoma/diagnosis , Female , Humans , Middle Aged , Skin Neoplasms/diagnosisABSTRACT
Induction of psoriasis following administration of beta blocker containing eye drops has rarely been documented. We report eight cases of psoriasis triggered by timolol eye drops. Since the clinical and histopathological features of this drug reaction are indistinguishable from those of idiopathic psoriasis, a thorough drug history should be taken in all patients, especially elderly ones, with recent onset of psoriasis.
Subject(s)
Adrenergic beta-Antagonists/adverse effects , Psoriasis/chemically induced , Timolol/adverse effects , Adrenergic beta-Antagonists/administration & dosage , Adult , Aged , Aged, 80 and over , Female , Glaucoma, Open-Angle/drug therapy , Humans , Male , Middle Aged , Ophthalmic Solutions , Timolol/administration & dosageABSTRACT
Dermatofibrosarcoma protuberans (DFSP) is a dermal and subcutaneous slow-growing tumor of intermediate malignancy. Different histological variants of DFSP have been described, depending on cellular and stromal peculiarities. Here, we report the histological features of a DFSP in which cells were frequently arrayed in cords and fascicles that were interweaved, conforming a peculiar braided pattern. This finding might pose difficulties in the differential diagnosis with neural neoplasms and expands the morphological spectrum of DFSP.
