Subject(s)
Eye Neoplasms/diagnosis , Lymphoma, Large B-Cell, Diffuse/diagnosis , Meningeal Neoplasms/diagnosis , Pseudotumor Cerebri/diagnosis , Adolescent , Antineoplastic Agents/therapeutic use , Diagnosis, Differential , Eye Neoplasms/drug therapy , Eye Neoplasms/physiopathology , Humans , Lymphoma, Large B-Cell, Diffuse/drug therapy , Male , Meningeal Neoplasms/drug therapy , Optic Disk/pathology , Visual Acuity , Visual FieldsABSTRACT
OBJECTIVE: To report the association between herpes simplex virus (HSV) and iris atrophy with pupillary dilation. DESIGN: Retrospective case series. PARTICIPANTS: Patients with a clinical diagnosis of HSV keratouveitis seen between November 1993 and April 1994 in a single university uveitis clinic. There were 6 women and 7 men, aged 17 to 69 years (mean age 44.4 years). METHODS: Patient information was collected, including history and medications used, and a complete ophthalmologic evaluation was performed, with careful documentation of iris detail and pupillary size. RESULTS: Thirteen of 13 patients demonstrated some degree of iris atrophy; 9 of 13 had pupillary dilation on the affected side despite not being on dilating drops. CONCLUSIONS: Iris atrophy and pupillary dilation in a patient with unexplained anterior uveitis suggests the diagnosis of HSV keratouveitis.
