Parents' acceptance to vaccinate children against COVID-19: A Syrian online survey.

After the widespread of COVID-19 virus worldwide, vaccination targeted reducing spread of cases and mortality rates. However, vaccination hesitancy was observed among the communities worldwide. Vaccination hesitancy involved parents regarding the decision of vaccinating their children- After obtaining ethical approval, an online cross-sectional study was conducted from 1 March to 22 April 2021 to evaluate the parents' acceptance of vaccinating their children against the COVID-19 virus in Syria. Data were analyzed using descriptive and multivariate logistic regression analysis in IBM, SPSS V. 28.0 package program (IBM Corporation, Armonk, NY, USA). Among 283 participants, 105 participants agreed to vaccinate their children, and 178 were not. A significant correlation between age and vaccine willingness was found (P-value < 0.0001*), especially in the age group between 18 and 30 years old (45.2%). Parents who accepted vaccinating themselves were more willing to vaccinate their children (34.6%). According to our results, there is a greater need to enhance awareness and knowledge programs about the vaccine's effectiveness and encourage parents to accept giving the vaccine to their children.

Peritoneal effusion as unusual complication post COVID 19 infection.

Introduction: COVID 19 is a new virus appeared in the late of 2019, and spread widely through the world, causing respiratory symptoms and sometimes could cause digestive manifestations. Case presentation: We reported a case of a 72 years old women presented with a complaint of dry cough, dyspnea and swollen abdomen, which she diagnosed with COVID19 and her medical history showed type 2 diabetes mellitus and acute kidney injury one month prior to her presentation. CT-abdomen showed Ascites and slightly hepatomegaly then we performed prednisolone antibiotics medication. After a week the Ascites decreased and her condition was good and stable. Discussion: Few similar cases have been reported in the literature as case reports, but our article reports the first case report from Syria, which may increase the clinical awareness towards rare complications of COVID19 infection among Syrian clinical doctors, especially pulmonologists. Conclusion: The peritoneal effusion consider as s rare digestive manifestation of COVID19 that Clinical doctors should take aware off.

Autoimmune polyglandular syndrome type 2: A case report.

Introduction: Autoimmune polyglandular syndrome 2(APS 2) is immune-mediated destruction that affects two or more endocrine glands and causes a constellation of multiple glands insufficiencies. Case presentation: we reported a rare case 9 years old male diagnosed with APS 2; he had adrenal insufficiency three years ago due to leak adherence to hydrocortisone. He was admitted to the hospital for adrenal crises after hemodynamic stability; laboratory evaluation showed that he had Hashimoto's thyroiditis, celiac disease, and the glutamic acid decarboxylase antibody (GAD) Anti-islet cell antibodies were positive, so he was also predisposed to DM 1 later. Discussion: APS 2, also known as Schmidt's syndrome, is usually defined by the occurrence of the same fludrocortisone or more of the followings: primary adrenal insufficiency (Addison's disease), Grave's disease, primary hypothyroidism, type 1 diabetes mellitus, celiac disease, and pernicious anemia. Conclusion: This case report underlines the importance of early recognition and treatment of acute endocrine diseases and the necessity to investigate pediatric patients with autoimmune diseases for coexisting conditions.

Tonic non-colonic convulsions-status epilepticus- as the presenting complaint of COVID-19.

Introduction: COVID19 might present as neurological symptoms including headaches, dizziness, anosmia, stroke, and loss of consciousness. Cases with severe COVID-19 are more likely to be complicated by neurological symptoms, but tonic non-colonic convulsion is still a rare presentation of COVID19 as an initial symptom. Case presentation: A 23-years old male presented to the ambulance with a complaint of loss of consciousness for more than 1 h and tonic convulsions without clonic movements. The investigations including computed tomography for the brain and chest and lumbar puncture were within normal range and the diagnostic workup concluded that COVID-19 is the cause of the status epilepticus. Discussion: Our case demonstrates a tonic non-clonic convulsion as a possible complication for COVID-19 infection as some respiratory viruses can cause neurological symptoms. After excluding the co-incidence of other pathological etiologies, we highly suspect that the seizures in our case are generated by COVID-19 infection. Conclusion: This case represents a rare case in the literature review which can increase the awareness of tonic non-clonic seizures and other neurological manifestations as the presenting symptom of the COVID19.