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Ann Vasc Surg ; 29(6): 1318.e1-6, 2015 Aug.
Article in English | MEDLINE | ID: mdl-26115610

ABSTRACT

Bacillus Calmette-Guérin (BCG) therapy is often associated with side effects. The most feared is disseminated sepsis that may occur rarely with the development of mycotic aortic aneurysms. Twenty cases of patients treated with intravesical BCG complicated by mycotic abdominal aortic aneurysm have been reported in the literature, including 2 cases of the present study. Delayed vascular work-up represents a critical aspect. Mycotic aneurysms evidence a rapid progression. Primary care physicians and urologists should be sensitized to recognize unspecified symptoms such as potential clinical manifestations of a mycotic abdominal aortic aneurysm, even several months or years after BCG therapy.


Subject(s)
Aneurysm, Infected/microbiology , Aortic Aneurysm, Abdominal/microbiology , Aortic Rupture/microbiology , BCG Vaccine/adverse effects , Urinary Bladder Neoplasms/therapy , Urothelium , Administration, Intravesical , Aged , Aged, 80 and over , Aneurysm, Infected/diagnosis , Aneurysm, Infected/surgery , Antitubercular Agents/therapeutic use , Aortic Aneurysm, Abdominal/diagnosis , Aortic Aneurysm, Abdominal/surgery , Aortic Rupture/diagnosis , Aortic Rupture/surgery , Aortography/methods , BCG Vaccine/administration & dosage , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Humans , Male , Neoplasm Invasiveness , Neoplasm Staging , Risk Factors , Time Factors , Tomography, X-Ray Computed , Treatment Outcome , Urinary Bladder Neoplasms/pathology , Urothelium/pathology
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