ABSTRACT
OBJECTIVES: To describe the natural history of AML, the clinical results and the need for treatment during long-term follow-up of renal AML. METHODS: Retrospective study of patients diagnosed with AML by computed tomography or nuclear magnetic resonance between 2001 and 2019, with at least two follow-up images. Clinical and imaging variables, need for intervention, complications and follow-up time were recorded. Statistical analysis was performed using SPSS 22.0. RESULTS: 111 patients and 145 AML were included. The median follow-up was 6.17 years (range 0.7-18.1, IQR 11.8-12.2). The median tumor size at diagnosis was 13 mm (IQR 7.5-30), with 24 (16.4%) being ≥ 4 cm. Most presented as an incidental finding (85.5%); in 3 (2.1%) cases, the presentation was as a spontaneous retroperitoneal hematoma. The main indication for intervention was size ≥ 4 cm in 50%. Eighteen (12%) patients received a first intervention, being urgent in 3. Embolization was performed in 15 cases and partial nephrectomy in 3. The need for reintervention was recorded in five: two underwent partial nephrectomy and two total nephrectomy; one patient required a new urgent embolization. Of the non-operated patients, 43% decreased in size or did not change, while 57% increased, with the median annual growth being 0.13 mm (IQR - 0.11 to 0.73). There were no differences in the median growth in tumors measuring ≥ 4 cm (0.16 mm) at diagnosis vs. < 4 cm (0.13 mm) (p = 0.9). CONCLUSIONS: The findings of this study suggest that AML typically demonstrate a slow-progressing clinical course during long-term follow-up. Moreover, our observations, which cast doubt on tumor size as a reliable predictor of adverse clinical outcomes, advocate for a less intensive monitoring strategy in both monitoring frequency and choice of imaging modality.
Subject(s)
Angiomyolipoma , Embolization, Therapeutic , Kidney Neoplasms , Leukemia, Myeloid, Acute , Humans , Angiomyolipoma/diagnostic imaging , Angiomyolipoma/surgery , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/surgery , Kidney Neoplasms/pathology , Follow-Up Studies , Retrospective Studies , Nephrectomy/methods , Embolization, Therapeutic/methods , Leukemia, Myeloid, Acute/complications , Leukemia, Myeloid, Acute/surgeryABSTRACT
INTRODUCTION: Paratesticular sarcoma is an aggressive malignant tumor of mesenchymal origin. The rhabdomyosarcoma is the most common among children. Rhabdomyosarcoma treatment consists of surgery, chemotherapy and radiotherapy. Prognosic depends on local recurrence and distant metastasis. MATERIAL AND METHODS: We present the case of a 16-year-old male, who in April 2016 underwent right radical orchiectomy surgery by testicular mass rapidly evolving, with pathological results indicating a paratesticular rhabdomyosarcoma. The extension study showed a precaval adenopathy suggestive of lymph node metastasis, therefore it was a high-grade rhabdomyosarcoma. There was an appropriate response after chemotherapy (Protocol EpSSG RMS2005) and we decided to perform a robotic lymphadenectomy. RESULTS: We performed a transperitoneal approach with 8 mm trocar and 12 mm optica trocar. We accessed the retroperitoneal space through a latero-colic incision. Then we performed a craniocaudal lymph node dissection until the aortic bifurcation. The surgical time was 240 min with a blood loss of 200 ml. There were no complications. The patient was discharged on the fourth day after surgery. Pathology showed metastasis of rhabdomyosarcoma without capsular rupture. After two months, we placed the left testicle into inguinal canal prior to radiotherapy. CONCLUSIONS: Robotic lymph node metastasis lymphadenectomy from paratesticular sarcomas is a feasible treatment with the advantage of minimally invasive surgery and acceptable morbidity.
Subject(s)
Rhabdomyosarcoma , Robotic Surgical Procedures , Testicular Neoplasms , Adolescent , Child , Humans , Lymph Node Excision/methods , Lymphatic Metastasis , Male , Orchiectomy , Rhabdomyosarcoma/pathology , Rhabdomyosarcoma/surgery , Robotic Surgical Procedures/methods , Testicular Neoplasms/pathology , Testicular Neoplasms/surgeryABSTRACT
OBJECTIVE: Epidemiological data on urolithiasis in Spain have appeared in publications especially local and regional level, with few referrals to Spanish national territory. The aim of this paper is to review and systematize the epidemiological data published on urolithiasis in Spain. METHODS: We reviewed publications in national and international scientific journals, meetings and conferences, and research reports (1977-2016). PubMed search (indexed papers) and manual bibliography search (not indexed works) were performed. Bibliometric data evaluated: Year of publication, geographic area, number of cases, sample type, study design and publishing format. Demographic systematization of data: age, age and frequency distribution by gender, family history, social stratum, profession, place of residence, ethnics, seasonality and dietary habits. RESULTS: Publications revised: 79 corresponding to 56 main authors. Selected publications with original data: 42 (2 composed by Part I and II, and 2 composed by paper and thesis), corresponding to 35 authors. Bibliometric and demographic data of all publications are displayed in tables, sorted by variables. CONCLUSIONS: The comprehensive review of studies on epidemiology in Spain constitutes a solid basis for future research about epidemiology of urolithiasis.
Subject(s)
Urolithiasis/epidemiology , Adolescent , Adult , Aged , Bibliometrics , Demography , Female , Humans , Male , Middle Aged , Socioeconomic Factors , Spain/epidemiology , Time Factors , Young AdultABSTRACT
OBJETIVO: Los datos epidemiológicos sobre urolitiasis en España han aparecido sobre todo en publicaciones de ámbito comarcal y autonómico, siendo escasas las de carácter nacional español. El objetivo de este trabajo es revisar y sistematizar los datos epidemiológicos publicados sobre urolitiasis en España en los distintos trabajos. MÉTODOS: Revisión de las publicaciones en revistas científicas nacionales e internacionales, reuniones y congresos, e informes de investigación (1977-2016). Búsqueda en PubMed (trabajos indexados) y rastreo bibliográfico manual (trabajos no indexados). Datos bibliométricos evaluados: año de publicación, zona geográfica, número de casos, tipo de muestra, diseño del estudio y formato de publicación. Datos demográficos sistematizados: edad, distribución de edad y frecuencia por género, antecedente familiar, estrato social, profesión, lugar de residencia, aspectos étnicos, estacionalidad y hábitos dietéticos. RESULTADOS: Publicaciones revisadas: 79, correspondientes a 56 autores principales. Publicaciones seleccionadas con datos originales: 42 (2 compuestas de parte I y II), correspondientes a 35 autores. Se muestran en tablas los datos bibliométricos y demográficos del conjunto de publicaciones, ordenados por variables. CONCLUSIONES: La revisión completa de trabajos sobre epidemiología en España constituye una base sólida para establecer futuras investigaciones epimiológicas sobre urolitiasis
OBJECTIVE: Epidemiological data on urolithiasis in Spain have appeared in publications especially local and regional level, with few referrals to Spanish national territory. The aim of this paper is to review and systematize the epidemiological data published on urolithiasis in Spain. METHODS: We reviewed publications in national and international scientific journals, meetings and conferences, and research reports (1977-2016). PubMed search (indexed papers) and manual bibliography search (not indexed works) were performed. Bibliometric data evaluated: Year of publication, geographic area, number of cases, sample systematization of data: age, age and frequency distribution by gender, family history, social stratum, profession, place of residence, ethnics, seasonality and dietary habits. RESULTS: Publications revised: 79 corresponding to 56 main authors. Selected publications with original data: 42 (2 composed by Part I and II, and 2 composed by paper and thesis), corresponding to 35 authors. Bibliometric and demographic data of all publications are displayed in tables, sorted by variables. CONCLUSIONS: The comprehensive review of studies on epidemiology in Spain constitutes a solid basis for future research about epidemiology of urolithiasis