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Rev Esp Enferm Dig ; 86(3): 651-4, 1994 Sep.
Article in Spanish | MEDLINE | ID: mdl-7986597

ABSTRACT

The purpose of the study was to determine whether a correlation between the radioisotopic "spleen-to-liver" ratio and the hepatic damage (according to Knodell's Index) exists in patients with chronic liver disease, in order to ascertain whether hepatic biopsy should be performed under visual (laparoscopic) control or not (blind liver biopsy). Thirty patients with inflammatory chronic hepatic disease were studied (9 chronic persistent hepatitis, 14 active chronic hepatitis and 7 hepatic cirrhosis). An inverse correlation was found between Knodell's Index and the "spleen-to-liver" ratio with moderate statistical significance (r = -0.46). In conclusion, the isotopic "spleen-to-liver" ratio correlates moderately well with the degree of hepatic damage and consequently it can only be used as orientation about the preferable way for obtaining a liver biopsy (laparoscopically or not).


Subject(s)
Liver Diseases/pathology , Liver/pathology , Spleen/pathology , Biopsy , Chronic Disease , Hepatitis, Chronic/diagnostic imaging , Hepatitis, Chronic/pathology , Humans , Liver/diagnostic imaging , Liver Diseases/diagnostic imaging , Radionuclide Imaging , Spleen/diagnostic imaging , Technetium Tc 99m Sulfur Colloid , Ultrasonography
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