ABSTRACT
This work was performed in hypertensive ISIAH and normotensive WAG rat strains. The latter was used as a control group. The general evaluation of behavior of the ISIAH and WAG rats tested in the open field, in the light-dark test, in the sound stress test, and in the fatigue test showed that the motor and exploratory activity provoked by an unfamiliar environment was much higher in the ISIAH rats as compared to the control WAG strain. Spontaneous locomotor activity of the ISIAH rats in the home cage was significantly lower as compared to the control WAG strain. This finding suggests that the ISIAH rats are hyperreactive in an novel environment. It is concluded that the hypertensive ISIAH rats are significantly different from the control WAG rats not only in the arterial blood pressure level, but also in behavioral patterns.
Subject(s)
Behavior, Animal/physiology , Hypertension/psychology , Animals , Blood Pressure/physiology , Exploratory Behavior/physiology , Male , Motor Activity/physiology , Rats , Rats, Inbred Strains , Species Specificity , Stress, Physiological/physiologyABSTRACT
NISAG rats with stress-induced arterial hypertension are characterized by hyperactivity of the sympathoadrenal system under rest conditions and during stress exposure.