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1.
Article in Russian | MEDLINE | ID: mdl-27801411

ABSTRACT

The topicality of the problem stated in the title of the this article is attributable to the lack of up-to-date information on the treatment of thermal skin wounds with the use of short wavelength ultraviolet radiation (UVR). The objective of the present study was to evaluate the effectiveness of the courses of short wavelength ultraviolet radiation under experimental conditions using a model of standardized thermal skin wounds in rabbits starting from the proliferative phase of the healing. MATERIAL AND METHODS: The experiments were carried out on 24 grey rabbits. The thermal wounds were inflicted using a special device at a temperature of 180 degrees Celsius with a 3 sec exposition. The BOP-4 apparatus operated in the 180-280 nm wavelength range was used to treat the wounds. The total length of the treatment course was 10 days with wound irradiation during 8 to 12 minutes every other day (a total of 5 irradiation sessions throughout the study period). The study methods included morphological ones (microscopy of hematoxylin-eosin and Van Gieson-stained samples, planimetry), hematological (complete blood count), biochemical (general clinical), and microbiological (wound infestation). RESULTS: The study has demonstrated the acceleration of the wound healing process as appeared from the contraction and epithelialization of the lesions, the reduction of microbial infestation, the improvement of the general condition of the animals, and positive dynamics of the hematological and biochemical parameters. CONCLUSION: The results of the present study give evidence that shortwave ultraviolet irradiation is a highly efficient method for the treatment of the thermal skin wounds and the data obtained themselves provide an additional confirmation of the evidence-based effectiveness of light therapy.


Subject(s)
Burns/therapy , Phototherapy/methods , Ultraviolet Rays , Wound Healing/radiation effects , Animals , Rabbits
2.
Antibiot Khimioter ; 60(3-4): 20-3, 2015.
Article in Russian | MEDLINE | ID: mdl-26415379

ABSTRACT

The data on inhibition of the growth of microorganisms of a characteristic spectrum and antibiotic resistance isolated from long-term healing wounds by light of various wave ranges are presented. The growing cultures on blood agar were exposed to polarized light, red and infrared, ultraviolet of medium- and short-wave continuous modes accustomed in physiotherapy of wounds.The effect of light in some way induced inhibition of the growth, but complete recovery was stated only after the use of ultraviolet light when confirmed quantitatively in terms of the CFU.


Subject(s)
Candida/radiation effects , Gram-Negative Bacteria/radiation effects , Gram-Positive Bacteria/radiation effects , Ultraviolet Therapy/methods , Anti-Bacterial Agents/pharmacology , Candida/drug effects , Candida/growth & development , Candida/isolation & purification , Colony Count, Microbial , Culture Media/chemistry , Gram-Negative Bacteria/drug effects , Gram-Negative Bacteria/growth & development , Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/drug effects , Gram-Positive Bacteria/growth & development , Gram-Positive Bacteria/isolation & purification , Humans , Infrared Rays , Ultraviolet Rays , Wound Healing/drug effects , Wound Healing/physiology , Wound Healing/radiation effects , Wounds and Injuries/drug therapy , Wounds and Injuries/microbiology , Wounds and Injuries/radiotherapy
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