Improving the bioavailability of manganese and meat quality of broilers by using hot-melt extrusion nano method.

1. Mineral excretion is an issue in the poultry industry. The use of micro minerals in nano form can increase bioavailability and decrease excretion rate. However, information concerning the bioavailability of nano manganese (Mn) in broiler chicks is limited.2. This experiment studied the influences of hot-melt extrusion (HME)-processed manganese sulphate on body weight gain, Mn bioavailability, nutrient digestibility and meat quality in broiler chicks fed a corn-soybean meal-based diet as a starter and grower phase. A total of 700 birds (Ross 308, 1-day-old) were randomly placed in 35 cages (20 birds per cage). The broiler chicks were fed one of seven experimental diets, which consisted of a control (without supplemental Mn), different levels of MnSO4 (IN-Mn60; 60, 120, and 200 mg/kg), or HME MnSO4 (HME-Mn; 60, 120, and 200 mg/kg).3. There was an increased serum Mn content in broilers fed diet supplemented with HME-Mn. In the grower phase, increased dietary Mn levels elevated the concentrations in the serum, liver, and tibia. There were increases in the excreta Mn content of broilers fed increasing levels. The supplementation of HME-Mn showed a lower percentage of abdominal fat compared with the IN-Mn treatment diets. Supplementation with HME-Mn decreased intramuscular fat compared with the diets supplemented with IN-Mn. The supplementation of HME-Mn decreased the thiobarbituric acid reactive substances (TBARS) at d 6 of age. The HME-Mn source showed a greater decrease in TBARS compared with the IN-Mn treatment.4. In conclusion, HME processing increased bioavailability and could be used as an environmentally friendly method to facilitate lower levels of Mn in the diet of broiler chickens.

Devolution of healthcare system in Kenya: progress and challenges.

OBJECTIVES: The aim of the present study was to systematically review the progress and challenges on the devolved healthcare system in Kenya. STUDY DESIGN: A systematic review design was adopted for the present study. METHODS: Literature search was on biomedical databases of the most recent available electronic data published in English, that is, between January 2012 and April 2020. The populations for eligible studies were stakeholders within the county governments, healthcare workers and community dwellers. The databases included PubMed, EMBASE and Google Scholar. The following were the key words used in the search: 'Devolution of Health' 'Health care system in Kenya' AND 'County Health Facilities' 'challenges' AND 'progress' AND 'Kenya'. Other literature sources were after screening of all the references of all the added articles. Before the development of search terms, we looked for appropriate Medical Subject Headings terms and applied with maximal truncations. The data were qualitatively analysed, and findings were presented by three thematic domains. RESULTS: The search generated 1109 articles, of which 23 articles met the inclusion criteria. Data were presented and organized under three thematic domains: (1) localised decision-making process, (2) improvement in structural development and (3) inadequate resources/funds/staff. CONCLUSION: This is a systematic review which, to the best of our knowledge, is the first study of its kind to present the available evidence on the progress and challenges on the devolved healthcare system in Kenya. The major findings of this review were as follows: there was improvement in the health structural development that was brought by devolution in the country. However, devolution is not free of challenges. The major challenges noted in the postdevolution era within the health sector include inadequate resources/funds from the national government and understaffed health facilities. The study recommends allocation of resources to counties commensurate with the devolved functions. The study calls out for further research on equity and equality of the devolved healthcare system in Kenya.