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1.
J Med Case Rep ; 17(1): 540, 2023 Dec 31.
Article in English | MEDLINE | ID: mdl-38160233

ABSTRACT

BACKGROUND: The incidence of esophageal atresia with tracheoesophageal fistula is 1 out of 3000-5000 live births. Its incidence in lower middle income countries is not known. The infants usually present with excessive secretions or choking while feeding and are at risk for aspiration. The outcome of these infants in lower middle income countries is not encouraging due to delays in referral, sepsis at presentation requiring preoperative stabilization, postoperative complications such as anastomosis leaks, pneumonia, and pneumothorax. CASE PRESENTATION: We present two African babies who were term infants at age 2 days (male) and 5 days (female) with diagnosis of esophageal atresia and tracheoesophageal fistula. The 5-day-old infant required preoperative stabilization due to sepsis and delayed surgery with a poor postoperative outcome. The 2-day-old infant was preoperatively stable and had a good postoperative outcome. The challenges faced in management of these two cases have been highlighted. CONCLUSION: Outcome of infants with esophageal atresia and tracheoesophageal fistula in lower middle income countries is not encouraging due to delays in referral and poor postoperative healing attributed to sepsis and recurrent pneumothorax. Timely referral, preoperative condition of the infant, and timely management has shown to be a contributory factor for an improved outcome.


Subject(s)
Esophageal Atresia , Pneumothorax , Sepsis , Tracheoesophageal Fistula , Female , Humans , Male , Anastomotic Leak/etiology , Anastomotic Leak/surgery , Esophageal Atresia/complications , Esophageal Atresia/surgery , Pneumothorax/complications , Postoperative Complications/surgery , Retrospective Studies , Sepsis/complications , Tracheoesophageal Fistula/diagnosis , Tracheoesophageal Fistula/surgery , Tracheoesophageal Fistula/complications , Infant, Newborn
2.
Pediatr Neurol ; 50(6): 655-7, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24842260

ABSTRACT

INTRODUCTION: Spinal teratomas are extremely rare; they constitute <0.5% of all spinal cord tumors. These rare tumors have nonspecific manifestations but in most cases are accompanied by neurological deficits. Rupture of a mature teratoma can cause chemical meningitis. PATIENT DESCRIPTION: A 7-year-old boy presented with paroxysmal abdominal pain and a history of recurrent aseptic meningitis. Kernig and Brudzinski signs were present. Lumber puncture revealed pleocytosis with no evidence of bacteria growth. Imaging of the spine revealed a cystic lesion in spinal cord at thoracic level 9-11. Endoscopic excision of the cyst was successfully performed. Surgical and histopathological findings confirmed extramedullary matured teratoma. CONCLUSIONS: As the symptomatic attacks of spontaneous rupture of spinal teratoma resemble presentations of Mollaret meningitis, spinal teratoma should be considered in the differential diagnosis of Mollaret meningitis. We describe a rare example of spinal teratoma causing recurrent meningitis. Spine imaging should be considered in individuals with recurrent aseptic meningitis as this promotes earlier diagnosis, more appropriate treatment, and improved neurological outcome.


Subject(s)
Meningitis/physiopathology , Spinal Cord Neoplasms/physiopathology , Teratoma/physiopathology , Child , Humans , Magnetic Resonance Imaging , Male , Meningitis/etiology , Neuroendoscopy , Neurosurgical Procedures , Spinal Cord Neoplasms/pathology , Spinal Cord Neoplasms/surgery , Teratoma/pathology , Teratoma/surgery , Treatment Outcome
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