ABSTRACT
OBJECTIVE: carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a personal series of gastrointestinal carcinoid tumors, and to compare it to those in the literature. PATIENTS AND METHODS: the medical records of 40 Caucasian patients with over 50 gastrointestinal carcinoid tumors (including multiple cases) who were seen for a period of 16 years (1994-2009) were reviewed. RESULTS: mean age at presentation was 52 years, 50% were females, and mean tumor size was 9.9 mm. Most were gastroduodenal (42.5%) or rectal (30%), and were treated endoscopically. Metastases and carcinoid syndrome (CS) were seen in 5% of patients. Survival at study endpoint was 85%. CONCLUSIONS: age and gender were consistent with the literature. There was an increase in gastroduodenal (multifocal) and rectal carcinoids, likely because the series was essentially endoscopical in nature (bias). There was a lower rate of CS and higher survival, likely due to earlier diagnosis and treatment.
Subject(s)
Carcinoid Tumor , Gastrointestinal Neoplasms , Adolescent , Adult , Aged , Aged, 80 and over , Carcinoid Tumor/diagnosis , Carcinoid Tumor/therapy , Female , Gastrointestinal Neoplasms/diagnosis , Gastrointestinal Neoplasms/therapy , Humans , Male , Middle Aged , Retrospective Studies , Young AdultABSTRACT
Objetivo: los tumores carcinoides (TC) son los tumores neuroendocrinos más frecuentes. Los digestivos se diagnostican en las piezas quirúrgicas, en la clínica, y mediante los métodos de imagen (endoscopia, ecoendoscopia, TAC y Octreoscan, etc.). El objetivo de este trabajo retrospectivo fue revisar una serie personal de tumores carcinoides digestivos y compararla con la literatura. Pacientes y métodos: se revisaron las historias clínicas de 40 pacientes de raza blanca con más de 50 tumores carcinoides digestivos, algunos múltiples, observados durante 16 años (1994- 2009). Resultados: la edad media de presentación fue 52 años, 50% mujeres, con un tamaño medio del tumor de 9,9 mm. La mayoría eran gastroduodenales (42,5%) y rectales (30%) y fueron tratados por vía endoscópica. Las metástasis y el síndrome carcinoide (SC) se observó en un 5% de los casos. La supervivencia en el momento de cerrar el estudio era del 85%. Conclusiones: la edad y el sexo fueron similares a lo descrito en la literatura. Hubo un aumento de los carcinoides gastroduodenales (multifocales) y rectales, probablemente porque la serie era fundamentalmente endoscópica (sesgo). Se observó una disminución de la aparición SC y un aumento de la supervivencia probablemente por un diagnóstico y tratamiento más precoz(AU)
Objective: carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a personal series of gastrointestinal carcinoid tumors, and to compare it to those in the literature. Patients and methods: the medical records of 40 Caucasian patients with over 50 gastrointestinal carcinoid tumors (including multiple cases) who were seen for a period of 16 years (1994- 2009) were reviewed. Results: mean age at presentation was 52 years, 50% were females, and mean tumor size was 9.9 mm. Most were gastroduodenal (42.5%) or rectal (30%), and were treated endoscopically. Metastases and carcinoid syndrome (CS) were seen in 5% of patients. Survival at study endpoint was 85%. Conclusions: age and gender were consistent with the literature. There was an increase in gastroduodenal (multifocal) and rectal carcinoids, likely because the series was essentially endoscopical in nature (bias). There was a lower rate of CS and higher survival, likely due to earlier diagnosis and treatment(AU)
Subject(s)
Humans , Male , Female , Middle Aged , Carcinoid Tumor/diagnosis , Carcinoid Tumor/surgery , Endoscopy , Neuroendocrine Tumors/diagnosis , Neuroendocrine Tumors/surgery , Microsurgery/methods , Carcinoid Tumor/physiopathology , Carcinoid Tumor , Retrospective Studies , Neuroendocrine Tumors/physiopathology , Neuroendocrine Tumors , 28599Subject(s)
Humans , Male , Female , Adult , Middle Aged , Helicobacter pylori/pathogenicity , Crohn Disease/complications , Crohn Disease/epidemiology , Colitis, Ulcerative/complications , Colitis, Ulcerative/diagnosis , Inflammatory Bowel Diseases/complications , Inflammatory Bowel Diseases/diagnosis , Sulfasalazine/therapeutic use , Mycobacterium avium subsp. paratuberculosis/pathogenicity , Enteritis/complications , Enteritis/diagnosis , Mycobacterium avium/isolation & purification , Mycobacterium avium/pathogenicity , Odds Ratio , Logistic ModelsABSTRACT
A review and update on 3D endoscopic ultrasonography is included regarding all of this technique s aspects, technical details, and current indications. Images from our own clinical experience are presented.
Subject(s)
Endosonography/methods , Gastrointestinal Diseases/diagnostic imaging , Imaging, Three-Dimensional , Humans , Rectal Diseases/diagnostic imagingABSTRACT
Se efectúa una revisión y puesta al día de la ultrasonografía endoscópica tridimensional en 3D, en todos sus aspectos, sus detalles técnicos y sus indicaciones actuales. Se presentan imágenes de experiencia propia
A review and update on 3D endoscopic ultrasonography is included regarding all of this technique's aspects, technical details, and current indications. Images from our own clinical experience are presented
Subject(s)
Humans , Endosonography/methods , Imaging, Three-Dimensional/methods , Laparoscopy/methods , Rectal Diseases/diagnosisABSTRACT
A review and update on tridimensional ultrasonography covering all its aspects, ultrasonography and 3D endoscopic ultrasonography, its technical details and current indications, such as volume calculation, vascular architecture assessment, and role in interventionist ultrasounds. Images included are from the author's own experience.
Subject(s)
Imaging, Three-Dimensional , Ultrasonography/methods , Gastrointestinal Diseases/diagnostic imaging , HumansABSTRACT
Se efectúa revisión y puesta al día de la ultrasonografía tridimensionalen 3D, en todas sus facetas, ecografía y ultrasonografíaendoscópica 3D, sus detalles técnicos y sus indicaciones actuales,como son el cálculo de volúmenes, la evaluación de la arquitecturavascular, y la ayuda a la ecografía intervencionista.Se presentan imágenes de experiencia propia
A review and update on tridimensional ultrasonography coveringall its aspects, ultrasonography and 3D endoscopic ultrasonography,its technical details and current indications, such as volumecalculation, vascular architecture assessment, and role ininterventionist ultrasounds.Images included are from the authors own experience