ABSTRACT
The article presents the results of the proximal small intestine parietal microbiocenosis research in patients with chronic pancreatitis by polymerase chain reaction in real time. The study includes an assessment of the pharmacological correction's efficiency in this category of patients.
Subject(s)
Intestinal Mucosa/microbiology , Intestine, Small/microbiology , Pancreatitis, Chronic/drug therapy , Pancreatitis, Chronic/microbiology , Adult , Case-Control Studies , Female , Humans , Male , Middle Aged , Pancreatitis, Chronic/etiology , Prebiotics/microbiology , Severity of Illness Index , Synbiotics , Treatment OutcomeABSTRACT
Study of the colon was carried out in patients with cholelithiasis after cholecystectomy. Estimated clinical symptoms, the mucous membrane status by the results of the histological, morphometric methods, computed ploidometry and immunomorphology of colon biopsy specimens. Mucosal atrophy, the buildup of sclerotic processes and proliferative activity of colonocytes was significantly more frequent in patients with cholecystectomy in history, than in patients with cholelithiasis and the control group. Most of the examined patients have disorders of the colon microbiocenosis. Use of domestic liquid synbiotic complexes Normoflorin L and B allowed to hold a successful correction of disbiosis.