Evaluación del impacto del confinamiento en jóvenes atendidos en centros comunitarios de salud mental / Avaluació de l'impacte del confinament en joves atesos en centres comunitaris de salut mental / Evaluation of the lockdown impact on young people in community mental health centres

mental. Elobjetivo de este estudio es analizar el impacto del confinamiento debido al virus del SARS-CoV-2 en la vida delos jóvenes atendidos en servicios de salud mental comunitarios. Se trata de un estudio observacional descrip-tivo transversal que se lleva a cabo entre junio y octubre del 2020 en una muestra de 41 jóvenes usuarios delCSMIJ, HDA y CSMA de la Asociación Centro de Higiene Mental Les Corts. Los resultados muestran que la situa-ción de confinamiento ha afectado en su salud física y mental, aunque el estar acompañados por la familia y unlugar de residencia óptimo les podría haber ayudado a afrontar mejor este período.(AU)

This study aims toanalyse the lockdown impact of the SARS-CoV-2 virus on the lives of young people attending community mentalhealth services. This is a cross-sectional descriptive observational study carried out between June and October2020 in a sample of 41 young users of the Mental Health centers and Day Care Hospital from Associació Centred’Higiene Mental Les Corts. The results show that the lockdown situation has affected their physical and mentalhealth, although being accompanied by the family and an optimal place of residence could have helped themto cope better with this period.(AU)

L'objectiud'aquest estudi és analitzar l'impacte del confinament a causa del virus de la SARS-CoV-2 a la vida dels joves ate-sos en serveis de salut mental comunitaris. Es tracta d’un estudi observacional descriptiu transversal que es porta aterme entre juny i octubre de l'any 2020 en una mostra de 41 joves usuaris del CSMIJ, HDA i CSMA de l’AssociacióCentre d’Higiene Mental Les Corts. Els resultats mostren que la situació de confinament ha afectat la seva salutfísica i mental, tot i que el fet d’estar acompanyats per la família i tenir un lloc de residència òptim els podria haverajudat a afrontar millor aquest període.(AU)

Neuropsychiatric manifestations in late-onset urea cycle disorder patients.

Inherited urea cycle disorders represent one of the most common groups of inborn errors of metabolism. Late-onset urea cycle disorders caused by partial enzyme deficiencies may present with unexpected clinical phenotypes. We report 9 patients followed up in our hospital presenting late-onset urea cycle disorders who initially manifested neuropsychiatric/neurodevelopmental symptoms (the most prevalent neuropsychiatric/neurodevelopmental diagnoses were mental retardation, attention-deficit hyperactivity disorder [ADHD], language disorder, and delirium). Generally, these clinical pictures did not benefit from pharmacological treatment. Conversely, dietary treatment improved the symptoms. Regarding biochemical data, 2 patients showed normal ammonium but high glutamine levels. This study highlights the fact that neuropsychiatric/neurodevelopmental findings are common among the initial symptomatology of late-onset urea cycle disorders. The authors recommend that unexplained or nonresponsive neuropsychiatric/neurodevelopmental symptoms appearing during childhood or adolescence be followed by a study of ammonia and amino acid plasmatic levels to rule out a urea cycle disorder.