ABSTRACT
Based on a case of gastric antral vascular ectasia (watermelon stomach) that was associated with hemorrhagic pericarditis, small cell lung carcinoma with mediastinal lymph node metastases and a synchronous squamous cell carcinoma of the base of the tongue, the authors made a review of the clinical, endoscopic and histopathological aspects of this type of gastropathy, and its association with other diseases, and of the results of its endoscopic therapy. The causes of hemorrhagic pericarditis are considered, emphasizing the necessity to know if the effusion has a malignant etiology. To the best of our knowledge the association of watermelon stomach to small cell lung carcinoma and squamous cell carcinoma of the base of the tongue has not yet been described. Extensive metastases to mediastal lymph nodes are common to small cell lung carcinoma.
Subject(s)
Carcinoma, Squamous Cell/complications , Gastric Antral Vascular Ectasia/complications , Hemorrhage/complications , Lung Neoplasms/complications , Neoplasms, Multiple Primary/complications , Pericarditis/complications , Small Cell Lung Carcinoma/complications , Tongue Neoplasms/complications , Fatal Outcome , Female , Humans , Middle AgedABSTRACT
Neurofibromatosis is a multisystemic disease in which the multiple possible clinical manifestations may have important diagnostic and prognostic implications; if arterial hypertension coexists, many pathogenic mechanisms justify that the possible secondary etiology must be considered. In this report we review the pathogenic and clinical mechanisms and we point to the diagnostic strategy to reveal anomalies and diseases that, although present, may be occult.
Subject(s)
Neurofibromatosis 1/complications , Bone Diseases/etiology , Endocrine System Diseases/etiology , Gastrointestinal Diseases/etiology , Humans , Neoplasms/etiology , Nervous System Diseases/etiology , Neurofibromatosis 1/diagnosis , Vascular Diseases/etiologyABSTRACT
Neurofibromatosis may involve every organ. Manifestations vary greatly and different kind of neoplasia may be associated with excessive frequency; it's the case of pheochromocytoma that, as a benign tumor, coexists in 10%. Description of coexistency as a malignant tumor is a rarity; therefore, we think it's interesting to publish our experience. Nevertheless the association of Von Recklinghausen's disease with hypertension is not always dependent of that kind of association.