Would you risk humanity's survival on a robot built in two years?

Project Hail Mary reflects real-world technical readiness assessment processes for robotics.

What to give your robot mother on Mother's Day.

Jung_E, the 2023 science-fiction movie from South Korea, suggests that a novel leg-wheel hybrid for robot locomotion might be appreciated.

LSD increases sleep duration the night after microdosing.

Microdosing psychedelic drugs at a level below the threshold to induce hallucinations is an increasingly common lifestyle practice. However, the effects of microdosing on sleep have not been previously reported. Here, we report results from a Phase 1 randomized controlled trial in which 80 healthy adult male volunteers received a 6-week course of either LSD (10 µg) or placebo with doses self-administered every third day. Participants used a commercially available sleep/activity tracker for the duration of the trial. Data from 3231 nights of sleep showed that on the night after microdosing, participants in the LSD group slept an extra 24.3 min per night (95% Confidence Interval 10.3-38.3 min) compared to placebo-with no reductions of sleep observed on the dosing day itself. There were no changes in the proportion of time spent in various sleep stages or in participant physical activity. These results show a clear modification of the physiological sleep requirements in healthy male volunteers who microdose LSD. The clear, clinically significant changes in objective measurements of sleep observed are difficult to explain as a placebo effect. Trial registration: Australian New Zealand Clinical Trials Registry: A randomized, double-blind, placebo-controlled trial of repeated microdoses of lysergic acid diethylamide (LSD) in healthy volunteers; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381476 ; ACTRN12621000436875.

Robot pack mules remain science fiction for now.

The plot of the 2014 science-fiction movie Young Ones revolves around a robot pack mule based on the real-world BigDog.

A fictional history of robotics features forgotten real-world robots.

The science-fiction movie The Creator uses six real-world robots from the 1950s and 1960s to show progress in AI.

Early science fiction got microbots surprisingly right.

Since 1931, science fiction has speculated on how microbots might work and how they will change our lives.

Modulation of long-term potentiation following microdoses of LSD captured by thalamo-cortical modelling in a randomised, controlled trial.

BACKGROUND: Microdosing psychedelics is a phenomenon with claimed cognitive benefits that are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing effects on neuroplasticity, which cannot be measured directly in humans, but may be indexed by non-invasive electroencephalography (EEG) paradigms. This study used a visual long-term potentiation (LTP) EEG paradigm to test the effects of microdosed lysergic acid diethylamide (LSD) on neural plasticity, both acutely while on the drug and cumulatively after microdosing every third day for six weeks. Healthy adult males (n = 80) completed the visual LTP paradigm at baseline, 2.5 h following a dose of 10 µg of LSD or inactive placebo, and 6 weeks later after taking 14 repeated microdoses. Visually induced LTP was used as indirect index of neural plasticity. Surface level event-related potential (ERPs) based analyses are presented alongside dynamic causal modelling of the source localised data using a generative thalamocortical model (TCM) of visual cortex to elucidate underlying synaptic circuitry. RESULTS: Event-related potential (ERP) analyses of N1b and P2 components did not show evidence of changes in visually induced LTP by LSD either acutely or after 6 weeks of regular dosing. However modelling the complete timecourse of the ERP with the TCM demonstrated changes in laminar connectivity in primary visual cortex. This primarily included changes to self-gain and inhibitory input parameters acutely. Layer 2/3 to layer 5 excitatory connectivity was also different between LSD and placebo groups. After regular dosing only excitatory input from layer 2/3 into layer 5 and inhibitory input into layer 4 were different between groups. CONCLUSIONS: Without modulation of the ERPs it is difficult to relate the findings to other studies visually inducing LTP. It also indicates the classic peak analysis may not be sensitive enough to demonstrate evidence for changes in LTP plasticity in humans at such low doses. The TCM provides a more sensitive approach to assessing changes to plasticity as differences in plasticity mediated laminar connectivity were found between the LSD and placebo groups. TRIAL REGISTRATION:  ANZCTR registration number ACTRN12621000436875; Registered 16/04/2021 https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381476 .

What will robots think of us?

Two recent science fiction novels humorously illustrate the importance of correct robot mental models.

Microdosing Psychedelics: Current Evidence From Controlled Studies.

Taking regular low doses of psychedelic drugs (microdosing) is a practice that has drawn recent scientific and media attention for its potential psychotherapeutic effects. Yet, controlled studies evaluating this practice have lagged. Here, we review recent evidence focusing on studies that were conducted with rigorous experimental control. Studies conducted under laboratory settings using double-blind placebo-controlled procedures and investigator-supplied drug were compiled. The review includes demographic characteristics of participants and dependent measures such as physiological, behavioral, and subjective effects of the drugs. Review criteria were met by 14 studies, all of which involved acute or repeated low (5-20 µg) doses of lysergic acid diethylamide (LSD). Acute microdoses of LSD dose-dependently altered blood pressure, sleep, neural connectivity, social cognition, mood, and perception of pain and time. Perceptible drug effects were reported at doses of 10 to 20 µg but not 5 µg. No serious adverse effects were reported. Repeated doses of LSD did not alter mood or cognition on any of the measures studied. The findings suggest that low doses of LSD are safe and produce acute behavioral and neural effects in healthy adults. Further studies are warranted to extend these findings to patient samples and to other psychedelic drugs and to investigate microdosing as a potential pharmacological treatment for psychiatric disorders.

Would life be better as a robot?

A collection of short stories from Africa and the diaspora explore transhumanism in the face of ecological collapse.

RescueNet: A High Resolution UAV Semantic Segmentation Dataset for Natural Disaster Damage Assessment.

Recent advancements in computer vision and deep learning techniques have facilitated notable progress in scene understanding, thereby assisting rescue teams in achieving precise damage assessment. In this paper, we present RescueNet, a meticulously curated high-resolution post-disaster dataset that includes detailed classification and semantic segmentation annotations. This dataset aims to facilitate comprehensive scene understanding in the aftermath of natural disasters. RescueNet comprises post-disaster images collected after Hurricane Michael, obtained using Unmanned Aerial Vehicles (UAVs) from multiple impacted regions. The uniqueness of RescueNet lies in its provision of high-resolution post-disaster imagery, accompanied by comprehensive annotations for each image. Unlike existing datasets that offer annotations limited to specific scene elements such as buildings, RescueNet provides pixel-level annotations for all classes, including buildings, roads, pools, trees, and more. Furthermore, we evaluate the utility of the dataset by implementing state-of-the-art segmentation models on RescueNet, demonstrating its value in enhancing existing methodologies for natural disaster damage assessment.

Is "suicide by droid" satire or a real possibility?

Zed: A Novel humorously illustrates the need for, and challenges facing, the European Union Artificial Intelligence Act.

"Robots for good": Ten defining questions.

Ten questions to guide reflection and assessment of the "good" in robotics projects are suggested.

Assistive robots would regret a robot uprising.

Sea of Rust projects a complex emotional relationship between assistive robots and humans.

Surgical robots in movies may not be science fiction.

RoboDoc, a 2009 comedy, offers a surprisingly accurate assessment of robot surgery.

Designing a robot to recover a sunken submarine is hard.

Three Miles Down is a fictionalized version of the expedition to recover a Soviet submarine, 50 years before OceanGate Titan.

Harnessing AI and robotics in humanitarian assistance and disaster response.

AI and robotics can facilitate humanitarian assistance and disaster response, but partnerships with practitioners are crucial.

Mars robots meet bounded rationality.

A new sci-fi novel, The Strange, is set in a counterfactual Mars where an alien mineral increases the intelligence of robots.

Sci-fi imagines how good brain-machine interfaces will amplify bad choices.

Machine Man and The Andromeda Evolution explore personal and societal ramifications of brain-machine interfaces.

No impaired integration in psychopathy: Evidence from an illusory conjunction paradigm.

Progress in psychopathy research has been hampered by ongoing contention about its fundamental cause. The Impaired Integration theory of psychopathy provides an attention-based account of information integration abnormalities. We set out to evaluate the suggested mechanism via an innovative application of the well-established illusory conjunction paradigm. Two hundred participants were recruited by utilizing a psychopathic-trait-maximization technique, sampling individuals from an ex-prisoner and a population sample. We found no support for information integration deficits in psychopathic individuals (BF10 = 0.156), and the absence of a relationship between psychopathic traits and illusory conjunctions remained when accounting for confounding variables. These findings question the mechanism proposed by the Impaired Integration theory and pave the way for future research to advance our understanding of psychopathic trait etiology by assessing specific and falsifiable mechanisms thought to bring about the observed cognitive and behavioral deficits. (PsycInfo Database Record (c) 2023 APA, all rights reserved).