The effect of cold chamber temperature on the cadaver's electrolyte changes in vitreous humor and plasma.

Determination of time since death is one of the important objectives of a medicolegal autopsy. The level of electrolytes present in the body fluids acts as a helpful indicator in this regard. Nowadays cold chambers are present in most of the autopsy centres where the body is stored for a variable period of time at a temperature which is different from the environmental temperature. This study was undertaken to know the effect of the cold chamber temperature on the changes in sodium, potassium and chloride levels of vitreous humor and plasma and also to estimate the time since death from the levels of these electrolytes. For this, the study subjects were exposed to the cold chamber temperature (in a range of +2 °C to +4 °C) for a variable duration of time before beginning the autopsy. The results obtained substantiate the fact that the temperature of the cold chamber has a significant effect on the change in vitreous humor potassium level. In subjects exposed to the cold chamber, there was a statistically significant negative correlation between the sodium and chloride levels of vitreous humor with time since death. The R-squared value for the regression equation to predict time since death from vitreous humor sodium level was found to be 0.0916 and was considered a significant predictor of time since death.

Histopathological Profile In Fatal Yellow Phosphorous Poisoning.

Yellow phosphorous (YP) is the toxic form of elemental phosphorous and the chief constituent of firecrackers and rodenticides. In India, the rodenticide paste is frequently used for the suicidal purpose. This study is an autopsy-based observational study which describes the histopathological features of heart, lungs, liver, and kidney of fatal cases of YP poisoning. The most common autopsy features in the viscera were congestion and petechial hemorrhage. The liver histopathology findings were microvesicular steatosis (68%), hepatic necrosis (62%), macrovesicular steatosis (50%), inflammatory cells (46%), sinusoidal congestion (40%), cholestasis (32%), and toxic hepatitis (18%). Hepatic necrosis ranged from being focal to centrizonal in distribution. Congestion was the most common feature observed in the lungs and the kidney. This is the largest autopsy-based study on YP poisoning till date. The histopathological features of liver were consistent with YP poisoning whereas the findings of heart, lungs, and kidney were nonspecific in nature.

Fatal Transorbital Intracranial Penetrating Injury Due to a Bicycle Brake Handle.

Transorbital intracranial injuries are uncommon and mostly accidental in nature. These injuries are usually associated with high mortality. The key to preventing this mortality involves an early diagnosis of intracranial injuries and immediate and appropriate management. Any delay can pose a serious risk to the patient's life. A case of a 55-year-old man who had experienced an accidental self-fall while riding a bicycle is presented. Initially, he was treated at a primary health center. He was referred to the tertiary care institute due to unavailability of ancillary investigation at the primary health center. He was declared dead on arrival at the casualty in the tertiary institute. On autopsy, it was observed that the injury above the right side of the upper eyelid was penetrating the right side roof of the orbit and the right cerebral cortex and brainstem. The highlighting feature of the case is that, despite the fatal penetrating brain injury, the eyeball did not sustain any major injury.