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Phytochemistry ; 66(6): 653-7, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15771885

ABSTRACT

From the acetone extract of the roots of Derris trifoliata an isoflavonoid derivative, named 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isoflavonoids (the sub-class is here named as rotenoloid), was isolated and characterised. In addition, the known rotenoids, rotenone, deguelin and alpha-toxicarol, were identified. The structures were determined on the basis of spectroscopic evidence. Rotenone and deguelin were identified as the larvicidal principles of the acetone extract of the roots of Derris trifoliata.


Subject(s)
Derris/chemistry , Insecticides/isolation & purification , Plant Roots/chemistry , Rotenone/analogs & derivatives , Rotenone/isolation & purification , Animals , Culex , Insecticides/pharmacology , Larva , Models, Molecular , Molecular Structure , Rotenone/pharmacology
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