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Bioorg Med Chem Lett
; 12(18): 2615-9, 2002 Sep 16.
Article
in English
| MEDLINE
| ID: mdl-12182873
ABSTRACT
Screening of the Roche compound library led to the identification of 4-aminoquinoline 4 as structurally novel NR1/2B subtype selective NMDA receptor antagonist. The SAR which was developed in this series resulted in the discovery of highly potent and in vivo active blockers.
