A novel approach based on neutrosophic Bonferroni mean operator of trapezoidal and triangular neutrosophic interval environments in multi-attribute group decision making.

Neutrosophic multicriteria is a method of decision-making that uses indeterminacy to combine several criteria or elements, frequently with incomplete or ambiguous information, to find a solution. The neutrosophic multicriteria analysis enables the assessment of qualitative and subjective aspects and can assist in resolving conflicting goals and preferences. In the Neutrosophic Multi-Attribute Group Decision Making (NMAGDM) problems, all the information provided by the decision makers (DMs) is expressed as single value neutrosophic triangular and trapezoidal numbers examined in this study which can provide more flexibility and accuracy in capturing uncertainty and aggregating preferences. We offer a novel approach for determining the neutrosophic possibility degree of two and three trapezoidal and triangular neutrosophic sets and the concepts of neutrosophic possibility mean value. The trapezoidal and triangular neutrosophic Bonferroni mean (TITRNBM) operator and the trapezoidal and triangular neutrosophic weighted Bonferroni mean (TITRNWBM) operator are two aggregation methods we then create. Further, we examine the TITRNBM and TITRNWBM attributes and their uniqueness. The NMAGDM approach with trapezoidal and triangular information is suggested based on the TITRNWBM operator and possibility degree. Finally, a concrete example of manufacturing companies searching for the best supplier for assembling the critical parts is provided to validate the established strategies and show their practical applicability and efficacy.

Computational design of mechanically coupled axle-rotor protein assemblies.

Natural molecular machines contain protein components that undergo motion relative to each other. Designing such mechanically constrained nanoscale protein architectures with internal degrees of freedom is an outstanding challenge for computational protein design. Here we explore the de novo construction of protein machinery from designed axle and rotor components with internal cyclic or dihedral symmetry. We find that the axle-rotor systems assemble in vitro and in vivo as designed. Using cryo-electron microscopy, we find that these systems populate conformationally variable relative orientations reflecting the symmetry of the coupled components and the computationally designed interface energy landscape. These mechanical systems with internal degrees of freedom are a step toward the design of genetically encodable nanomachines.

Bone density assessment for evaluation of gender differences in cervical vertebral maturation: A computed tomography study.

INTRODUCTION: The cervical vertebral maturation (CVM) method is a vital tool for assessing the biological maturation of the orthodontic patient to evaluate the amount of mandibular bone growth left. AIM: To assess and visualize the cervical vertebral morphology (bone density) of orthodontic patients of the age group 9,16,27 years. MATERIAL AND METHODS: Twenty four subjects with age group of 9,16,27 who were randomly selected and subjected to 3d tomographic study to estimate the biological age of the orthodontic patients by analyzing c1 c2 and c3 vertebrae. RESULT: The results showed that bone density of males is lesser than females in 9 and 16 years, whereas they have more bone density than females in 27 years. CONCLUSION: The study provides qualitative method of assessing the biological age of the patient by using images of cervical vertebrae by three dimensional approach. Hence it can be useful for orthodontic diagnosis and treatment plan.

Comparison and ranking of superelasticity of different austenite active nickel-titanium orthodontic archwires using mechanical tensile testing and correlating with its electrical resistivity.

INTRODUCTION: The application of light and continuous forces for optimum physiological response and the least damage to the tooth supporting structures should be the primary aim of an orthodontist. Nickel-titanium (NiTi) alloys with their desirable properties are one of the natural choices of the clinicians. AIM: This study was aimed to compare and rank them based on its tensile strength and electrical resistivity. MATERIALS AND METHODS: The sample consisted of eight groups of 0.017 inch × 0.025 inch rectangular archwires from eight different manufacturers, and five samples from each group for tensile testing and nine samples for electrical resistivity tests were used. Data for stress at 10% strain and the initial slope were statistically analyzed with an analysis of variance and Scheffe tests with P < 0.05. The stress/strain plots of each product were ranked for superelastic behavior. The rankings of the wires tested were based primarily on the unloading curve's slope which is indicative of the magnitude of the deactivation force and secondarily on the length of the horizontal segment which is indicative of continuous forces during deactivation. For calculating the electric resistivity, the change in resistance after inducing strain in the wires was taken into account for the calculation of degree of martensite transformation and for ranking. RESULTS: In tensile testing Ortho Organizers wires ranked first and GAC Lowland NiTi wires ranked last. For resistivity tests Ormco A wires were found superior and Morelli remained last. CONCLUSION: these rankings should be correlated clinically and need further studies.

Use of Ivabradine in Postural Orthostatic Tachycardia Syndrome.

Postural orthostatic tachycardia syndrome (POTS) is characterized by inappropriate increase in heart rate on assuming upright position from a supine position without a necessary drop in blood pressure. Etiology of this condition is complex and multifactorial. Autonomic dysfunction,[1] hypovolemia,[2] hyper responsiveness of beta adrenergic receptors[3] with associated elevations of plasma norepinephrine levels have been implicated as underlying pathophysiologic mechanisms. Beta blockers have previously been used to treat this condition. Ivabradine which selectively inhibits If ion current in the sino atrial node, has been reported to be useful in patients with POTS.[4,5] We present one further such case of POTS successfully treated by Ivabradine.

Reversible acute myocardial injury following air bag deployment.

This case report is about a 62 year old woman who was involved in an accident while driving her car, during which the driver side air bag deployed. She experienced intense anterior chest pain that radiated to her left arm after the accident, but was otherwise well; there was no significant medical history. An electrocardiogram done one and half hours after admission revealed 1 mm ST segment elevation in leads V2 and V3 and troponin 1 level was raised. She underwent cardiac catheterisation but three months after the accident both ECG and echocardiographic studies were normal. It is suggested that she underwent cardiac contusion rather than a myocardial infarction.