1.
J Org Chem
; 80(4): 2037-41, 2015 Feb 20.
Article
in English
| MEDLINE
| ID: mdl-25621816
ABSTRACT
An asymmetric Diels-Alder reaction of 2,4-dienols and methyl acrylate utilizing a chiral Zn(II)/Mg(II) bimetallic template with low catalyst loading was successfully achieved. The bimetallic Lewis acid template derived from (R)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol catalyzed the Diels-Alder reaction in the presence of molecular sieves 4 Što afford various functionalized bicyclic γ-lactones with high enantiomeric purities.