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1.
Comput Methods Programs Biomed ; 165: 163-174, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30337071

ABSTRACT

BACKGROUND AND OBJECTIVE: Melanoma is one of the major death causes while basal cell carcinoma (BCC) is the utmost incident skin lesion type. At their early stages, medical experts may be confused between both types with benign nevus and pigmented benign keratoses (BKL). This inspired the current study to develop an accurate automated, user-friendly skin lesion identification system. METHODS: The current work targets a novel discrimination technique of four pre-mentioned skin lesion classes. A novel proposed texture feature, named cumulative level-difference mean (CLDM) based on the gray-level difference method (GLDM) is extracted. The asymmetry, border irregularity, color variation and diameter are summed up as the ABCD rule feature vector is originally used to classify the melanoma from benign lesions. The proposed method improved the ABCD rule to also classify BCC and BKL by using the proposed modified-ABCD feature vector. In the modified set of ABCD features, each border feature, such as compact index, fractal dimension, and edge abruptness is considered a separate feature. Then, the composite feature vector having the pre-mentioned features is ranked using the Eigenvector Centrality (ECFS) feature ranking method. The ranked features are then classified by a cubic support vector machine for different numbers of selected features. RESULTS: The proposed CLDM texture features combined with the ranked ABCD features achieved outstanding performance to classify the four targeted classes (melanoma, BCC, nevi and BKL). The results report 100% outstanding performance of the sensitivity, accuracy and specificity per each class compared to other features when using the highest seven ranked features. CONCLUSIONS: The proposed system established that Melanoma, BCC, nevus and BKL are efficiently classified using cubic SVM with the new feature set. In addition, the comparative studies proved the superiority of the cubic SVM to classify the four classes.


Subject(s)
Diagnosis, Computer-Assisted/methods , Skin Diseases/diagnostic imaging , Skin Neoplasms/diagnostic imaging , Algorithms , Carcinoma, Basal Cell/classification , Carcinoma, Basal Cell/diagnostic imaging , Carcinoma, Basal Cell/pathology , Carcinoma, Squamous Cell/classification , Carcinoma, Squamous Cell/diagnostic imaging , Carcinoma, Squamous Cell/pathology , Databases, Factual , Dermoscopy/methods , Diagnosis, Computer-Assisted/statistics & numerical data , Diagnosis, Differential , Fractals , Humans , Image Interpretation, Computer-Assisted/methods , Image Interpretation, Computer-Assisted/statistics & numerical data , Keratosis/classification , Keratosis/diagnostic imaging , Keratosis/pathology , Melanoma/classification , Melanoma/diagnostic imaging , Melanoma/pathology , Nevus, Pigmented/classification , Nevus, Pigmented/diagnostic imaging , Nevus, Pigmented/pathology , Pattern Recognition, Automated/methods , Pattern Recognition, Automated/statistics & numerical data , Skin/diagnostic imaging , Skin/pathology , Skin Diseases/classification , Skin Diseases/pathology , Skin Neoplasms/classification , Skin Neoplasms/pathology , Support Vector Machine
2.
Health Inf Sci Syst ; 5(1): 10, 2017 Dec.
Article in English | MEDLINE | ID: mdl-29142740

ABSTRACT

PURPOSE: Basal cell carcinoma is one of the most common malignant skin lesions. Automated lesion identification and classification using image processing techniques is highly required to reduce the diagnosis errors. METHODS: In this study, a novel technique is applied to classify skin lesion images into two classes, namely the malignant Basal cell carcinoma and the benign nevus. A hybrid combination of bi-dimensional empirical mode decomposition and gray-level difference method features is proposed after hair removal. The combined features are further classified using quadratic support vector machine (Q-SVM). RESULTS: The proposed system has achieved outstanding performance of 100% accuracy, sensitivity and specificity compared to other support vector machine procedures as well as with different extracted features. CONCLUSION: Basal Cell Carcinoma is effectively classified using Q-SVM with the proposed combined features.

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