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1.
Nature ; 615(7953): 597-604, 2023 03.
Article in English | MEDLINE | ID: mdl-36949335

ABSTRACT

Recent developments have ushered in a new era in the field of black-hole astrophysics, providing a direct view of the remarkable environment near black-hole event horizons. These observations have enabled astronomers to confirm long-standing ideas on the physics of gas flowing into black holes with temperatures that are hundreds of times greater than at the centre of the Sun. At the same time, the observations have conclusively shown that light rays near a black hole experience large deflections that cause a dark shadow in the centre of the image, an effect predicted by Einstein's theory of general relativity. With further investment, this field is poised to deliver decades of advances in our understanding of gravity and black holes through stringent tests of general relativity, as well as insights into the role of black holes as the central engines powering a wide range of astronomical phenomena.

2.
Article in English | MEDLINE | ID: mdl-33842188

ABSTRACT

In this article, the binding abilities of arginine, citrulline, N-acetyl citrulline and thiocitrulline on the active sites of SARS-COV-2 protease have been investigated using in-silico studies. All the above ligands bind selectively and preferentially to Cys-145 active site and also to other amino acids surrounding to it in the main protease. Of which arginine forms less number of weaker bonds compared to the other ligands, it by itself is a precursor for the formation of citrulline analogues with in the cell. Major advantage of using the above ligands is that in addition to its preferential binding, they have the ability to increase the immunity by assisting NO generation. Our results show that N-acetyl citrulline, citrulline, thiocitrulline and arginine may be used as a supplement during the treatment of SARS-COV-2.

3.
Sci Adv ; 6(12): eaaz1310, 2020 Mar.
Article in English | MEDLINE | ID: mdl-32206723

ABSTRACT

The Event Horizon Telescope image of the supermassive black hole in the galaxy M87 is dominated by a bright, unresolved ring. General relativity predicts that embedded within this image lies a thin "photon ring," which is composed of an infinite sequence of self-similar subrings that are indexed by the number of photon orbits around the black hole. The subrings approach the edge of the black hole "shadow," becoming exponentially narrower but weaker with increasing orbit number, with seemingly negligible contributions from high-order subrings. Here, we show that these subrings produce strong and universal signatures on long interferometric baselines. These signatures offer the possibility of precise measurements of black hole mass and spin, as well as tests of general relativity, using only a sparse interferometric array.

4.
Science ; 350(6265): 1242-5, 2015 Dec 04.
Article in English | MEDLINE | ID: mdl-26785487

ABSTRACT

Near a black hole, differential rotation of a magnetized accretion disk is thought to produce an instability that amplifies weak magnetic fields, driving accretion and outflow. These magnetic fields would naturally give rise to the observed synchrotron emission in galaxy cores and to the formation of relativistic jets, but no observations to date have been able to resolve the expected horizon-scale magnetic-field structure. We report interferometric observations at 1.3-millimeter wavelength that spatially resolve the linearly polarized emission from the Galactic Center supermassive black hole, Sagittarius A*. We have found evidence for partially ordered magnetic fields near the event horizon, on scales of ~6 Schwarzschild radii, and we have detected and localized the intrahour variability associated with these fields.

5.
Phys Rev Lett ; 111(5): 051303, 2013 Aug 02.
Article in English | MEDLINE | ID: mdl-23952384

ABSTRACT

Magnetic fields appear to be present in all galaxies and galaxy clusters. Recent measurements indicate that a weak magnetic field may be present even in the smooth low density intergalactic medium. One explanation for these observations is that a seed magnetic field was generated by some unknown mechanism early in the life of the Universe, and was later amplified by various dynamos in nonlinear objects like galaxies and clusters. We show that a primordial magnetic field is expected to be generated in the early Universe on purely linear scales through vorticity induced by scale-dependent temperature fluctuations, or equivalently, a spatially varying speed of sound of the gas. Residual free electrons left over after recombination tap into this vorticity to generate magnetic field via the Biermann battery process. Although the battery operates even in the absence of any relative velocity between dark matter and gas at the time of recombination, the presence of such a relative velocity modifies the predicted spatial power spectrum of the magnetic field. At redshifts of order a few tens, we estimate a root mean square field strength of order 10(-25)-10(-24) G on comoving scales ~10 kpc. This field, which is generated purely from linear perturbations, is expected to be amplified significantly after reionization, and to be further boosted by dynamo processes during nonlinear structure formation.

6.
Science ; 321(5887): 376-9, 2008 Jul 18.
Article in English | MEDLINE | ID: mdl-18583579

ABSTRACT

We determined some basic properties of stars that produce spectacular gamma-ray bursts at the end of their lives. We assumed that accretion of the outer portion of the stellar core by a central black hole fuels the prompt emission and that fall-back and accretion of the stellar envelope later produce the plateau in the x-ray light curve seen in some bursts. Using x-ray data for three bursts, we estimated the radius of the stellar core to be approximately (1 - 3) x 10(10) cm and that of the stellar envelope to be approximately (1 - 2) x 10(11) cm. The density profile in the envelope is fairly shallow, with rho approximately r(-2) (where rho is density and r is distance from the center of the explosion). The rotation speeds of the core and envelope are approximately 0.05 and approximately 0.2 of the local Keplerian speed, respectively.

7.
Nature ; 449(7164): 872-5, 2007 Oct 18.
Article in English | MEDLINE | ID: mdl-17943124

ABSTRACT

Stellar-mass black holes are found in X-ray-emitting binary systems, where their mass can be determined from the dynamics of their companion stars. Models of stellar evolution have difficulty producing black holes in close binaries with masses more than ten times that of the Sun (>10; ref. 4), which is consistent with the fact that the most massive stellar black holes known so far all have masses within one standard deviation of 10. Here we report a mass of (15.65 +/- 1.45) for the black hole in the recently discovered system M 33 X-7, which is located in the nearby galaxy Messier 33 (M 33) and is the only known black hole that is in an eclipsing binary. To produce such a massive black hole, the progenitor star must have retained much of its outer envelope until after helium fusion in the core was completed. On the other hand, in order for the black hole to be in its present 3.45-day orbit about its (70.0 +/- 6.9) companion, there must have been a 'common envelope' phase of evolution in which a significant amount of mass was lost from the system. We find that the common envelope phase could not have occurred in M 33 X-7 unless the amount of mass lost from the progenitor during its evolution was an order of magnitude less than what is usually assumed in evolutionary models of massive stars.

8.
Science ; 307(5706): 77-80, 2005 Jan 07.
Article in English | MEDLINE | ID: mdl-15637269

ABSTRACT

Black holes are most often detected by the radiation produced when they gravitationally pull in surrounding gas, in a process called accretion. The efficiency with which the hot gas radiates its thermal energy strongly influences the geometry and dynamics of the accretion flow. Both radiatively efficient thin disks and radiatively inefficient thick disks are observed. When the accreting gas gets close to the central black hole, the radiation it produces becomes sensitive to the spin of the hole and the presence of an event horizon. Analysis of the luminosities and spectra of accreting black holes has yielded tantalizing evidence for both rotating holes and event horizons. Numerical simulations imply that the relativistic jets often seen from accreting black holes may be powered in part by the spin of the hole.

9.
Nature ; 425(6961): 908-9, 2003 Oct 30.
Article in English | MEDLINE | ID: mdl-14586450
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