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Klin Med (Mosk) ; 75(2): 31-3, 1997.
Article in Russian | MEDLINE | ID: mdl-9157211

ABSTRACT

The study of free-radical processes elucidated concentrations of O2 producing a negative effect in chronic obstructive bronchitis sufferers with respiratory insufficiency (RI). In RI of the second and third degree concentration of inhaled O2 should not exceed 50%. In this concentration O2 toxicity is not evident, unbalance of the system free radical-antiradical activity is less pronounced, O2 transport from the lungs to the tissue reaches optimal level. A course of oxygen therapy (20 daily sessions lasting 30 min., 50% O2) is not toxic, promoted activation of SOD and alleviation of arterial hypoxemia.


Subject(s)
Oxygen Inhalation Therapy/methods , Oxygen/administration & dosage , Respiratory Insufficiency/therapy , Blood Gas Analysis , Chronic Disease , Dose-Response Relationship, Drug , Free Radicals/metabolism , Humans , Oxygen/adverse effects , Oxygen Consumption , Oxygen Inhalation Therapy/adverse effects , Respiratory Insufficiency/metabolism , Superoxide Dismutase/metabolism
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