Subject(s)
Humans , Male , Female , Infant, Newborn , Adult , Renal Dialysis , Hypertension/drug therapy , Pregnancy ComplicationsABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Lipodystrophy/complications , Glomerulonephritis, Membranous/etiologyABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Proteinuria/etiology , Glomerulonephritis, IGA/etiology , Kidney Diseases/etiology , Hepatolenticular Degeneration/chemically induced , Nephrotic Syndrome/chemically induced , Proteinuria/pathology , Enkephalin, D-Penicillamine (2,5)-/adverse effects , Zinc Acetate/administration & dosage , Fibrinolytic Agents/administration & dosage , Ceruloplasmin/administration & dosage , Copper/urine , Nephrotic Syndrome/complications , Nephrotic Syndrome/drug therapy , Enkephalin, D-Penicillamine (2,5)-/administration & dosageSubject(s)
Humans , Male , Middle Aged , Renal Dialysis , Renal Insufficiency, Chronic/therapy , IgA Deficiency/etiology , Risk FactorsSubject(s)
Hypersensitivity, Immediate/complications , IgA Deficiency/etiology , Kidney Failure, Chronic/complications , Renal Dialysis , Adrenal Cortex Hormones/therapeutic use , Angioedema/etiology , CD4-CD8 Ratio , Cardiac Tamponade/surgery , Comorbidity , Emergencies , Hemodiafiltration , Humans , Hypersensitivity, Immediate/drug therapy , Hypotension/etiology , IgA Deficiency/blood , IgA Deficiency/drug therapy , Immunoglobulin E/immunology , Kidney Failure, Chronic/therapy , Lymphopenia/etiology , Middle Aged , Pericardiocentesis , Renal Dialysis/adverse effects , Water-Electrolyte Imbalance/etiologyABSTRACT
No disponible
Subject(s)
Humans , Female , Pregnancy , Adult , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/complications , Pre-Eclampsia/physiopathology , Pregnancy Complications/diagnosisABSTRACT
AA (secondary) amyloidosis is one of the most severe and uncommon complications of several rheumatic disorders and chronic infections such as tuberculosis (TB). Successful treatment depends on the control of the underlying inflammatory process, what can lead to an improvement or a regression in organ dysfunction. If the disorder persists, it has been reported in some cases of AA amyloidosis secondary to rheumatic diseases, that the use of biologic therapy is so far the only opportunity to reduce the development of AA amyloidosis and to reverse established deposits. We report herein a case of a latent TB infection complicated by a life-threatening AA amyloidosis presented as nephrotic syndrome. After an adequate antituberculostatic treatment, AA amyloidosis remained active and Tocilizumab (TCZ) was started with a dramatic resolution of the proteinuria, stabilization of the amyloid deposits and improvement in general condition.