1.
Ann Oncol
; 35(6): 569-570, 2024 Jun.
Article
in English
| MEDLINE
| ID: mdl-38548063
2.
Cancer Radiother
; 28(1): 83-92, 2024 Feb.
Article
in English
| MEDLINE
| ID: mdl-37620212
ABSTRACT
Head and neck carcinomas are initially metastatic in about 15% of cases. Radiotherapy is a cornerstone in the multimodal strategy at the locoregional phase. In patients with head and neck cancer, often heavily pretreated and with comorbidities, who relapse locoregionally or at distant sites, radiotherapy has also become increasingly important at the metastatic phase. Data on the optimal sequence of systemic treatments and metastasis-directed treatments including stereotactic irradiation are still lacking. Several randomized head and neck trials have been initiated that should provide important answers, including one recent GORTEC trial.