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Antibody responses of goldfish (Carassius auratus L.) to DNA-immunisation at different temperatures and feeding levels.
Russell, P H; Kanellos, T; Negrou, M; Ambali, A A.
Vaccine ; 18(22): 2331-6, 2000 May 08.
Article in English | MEDLINE | ID: mdl-10738088

ABSTRACT

DNA vaccines which work in winter are needed for fish. At 18 weeks after intramuscular injection of a plasmid containing lacZ goldfish at 15 degrees C had five-fold more antibody to betagalactosidase than those at 25 degrees C or those at

Subject(s)
Goldfish/immunology , Vaccines, DNA/administration & dosage , Animals , Antibody Formation , Eating , Gene Expression , Injections, Intramuscular , Lac Operon , Muscle Fibers, Skeletal/enzymology , Plasmids/genetics , Seasons , Temperature , Vaccines, DNA/genetics , beta-Galactosidase/genetics , beta-Galactosidase/immunology
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