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1.
Respir Med ; 108(12): 1771-8, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25459450

ABSTRACT

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. AIM: To investigate the effect of a comprehensive COPD management programme in decreasing COPD readmissions 1 year before and 1 year after the programme. METHOD: 185 (166 males) patients admitted for acute exacerbation of COPD (AECOPD) were recruited between September 2010 and December 2012. COPD care team provided crisis support and maintenance therapy for the COPD patients for a total of 16 weeks. The protocol included COPD clinic run by respiratory physicians, COPD education and nurse clinics by respiratory nurses, out-patient pulmonary rehabilitation programme by physiotherapists, fast track doctor's clinic, telephone hotline for patients and nurse telephone calls to patients. Readmissions over a period of 1 year were assessed. RESULTS: The mean (SD) age of the subjects and FEV1 % predicted normal were 76.9 ± 7.37 yrs and 44.4 ± 20.7% respectively. 40 (21.6%) patients required non-invasive positive pressure ventilation during the recruitment admission. Admissions for AECOPD decreased from 2.39 ± 2.05 one year before programme to 1.65 ± 2.1 one year after programme (mean difference 0.75 ± 2.11 episodes, p < 0.001). The length of hospital stay was reduced from 12.17 ± 9.14 days one year before programme to 9.09 ± 12.1 days one year after the programme (mean difference 3.09 ± 12.1 days, p < 0.001). The FEV1 percentage predicted and quality of life measured by St George's Respiratory Questionnaire showed no significant improvement at 16 weeks after recruitment into the programme as compared to at 6 weeks. CONCLUSION: COPD care programme is effective in decreasing readmissions and length of hospital day for COPD patients.


Subject(s)
Managed Care Programs , Patient Readmission/statistics & numerical data , Pulmonary Disease, Chronic Obstructive/therapy , Acute Disease , Aged , Aged, 80 and over , Delivery of Health Care, Integrated/organization & administration , Exercise Tolerance/physiology , Female , Hong Kong , Humans , Length of Stay/statistics & numerical data , Male , Patient Care Team/organization & administration , Program Evaluation , Pulmonary Disease, Chronic Obstructive/physiopathology , Quality of Life
2.
Respirology ; 17(2): 370-8, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22107482

ABSTRACT

BACKGROUND AND OBJECTIVE: This study assessed the asthma control test (ACT) cut-off values for asthma control according to the Global Initiative for Asthma guideline in adults and the effectiveness of ACT scores in predicting exacerbations and serial changes in ACT scores over time in relation to treatment decisions. METHODS: Subjects completed ACT together with same-day spirometry and fractional concentration of exhaled nitric oxide (FeNO) measurement at baseline and at 3 months. Physicians, blinded to the ACT scores and FeNO values, assessed the patient's asthma control in the past month and adjusted the asthma medications according to management guidelines. Asthma exacerbations and urgent health-care utilization (HCU) at 6 months were recorded. RESULTS: Three hundred seventy-nine (120 men) asthmatics completed the study. The ACT cut-off for uncontrolled and partly controlled asthma were ≤19 (sensitivity 0.74, specificity 0.67, % correctly classified 69.5) and ≤22, respectively (sensitivity 0.73, specificity 0.71, % correctly classified 72.1). Baseline ACT score had an odds ratio of 2.34 (95% confidence interval: 1.48-3.69) and 2.66 (1.70-4.18) for urgent HCU and exacerbations, respectively, at 6 months (P < 0.0001). However, baseline FeNO and spirometry values had no association with urgent HCU and exacerbations. The 3-month ACT score of ≤20 correlated best with step-up of asthma medications (sensitivity 0.65, specificity 0.81, % correctly classified 72.8). For serial changes of ACT scores over 3 months, the cut-off value was best at ≤3 for treatment decisions with low sensitivity (0.23) and % correctly classified (57.3%) values. CONCLUSIONS: Single measurement of ACT is useful for assessing asthma control, prediction of exacerbation and changes in treatment decisions.


Subject(s)
Asthma/diagnosis , Asthma/physiopathology , Adolescent , Adult , Aged , Aged, 80 and over , Breath Tests/methods , Exhalation , Female , Follow-Up Studies , Forced Expiratory Volume , Humans , Male , Middle Aged , Nitric Oxide/analysis , Predictive Value of Tests , Quality of Life , ROC Curve , Recurrence , Reproducibility of Results , Retrospective Studies , Spirometry/methods , Surveys and Questionnaires , Young Adult
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