ABSTRACT
BACKGROUND: Lung transplant recipients have an increased risk for actinomycetales infection secondary to immunosuppressive regimen. CASE PRESENTATION: A case of pulmonary infection with bacteremia due to Tsukamurella tyrosinosolvens in a 54-year old man who underwent a double lung transplantation four years previously is presented. CONCLUSION: The identification by conventional biochemical assays was unsuccessful and hsp gene sequencing was used to identify Tsukamurella tyrosinosolvens.
Subject(s)
Actinomycetales Infections/diagnosis , Actinomycetales/isolation & purification , Bacteremia/diagnosis , Pneumonia, Bacterial/diagnosis , Actinomycetales Infections/microbiology , Bacteremia/microbiology , Bacterial Typing Techniques , Cluster Analysis , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , Heat-Shock Proteins/genetics , Humans , Immunocompromised Host , Lung Transplantation/adverse effects , Male , Middle Aged , Molecular Sequence Data , Pneumonia, Bacterial/microbiology , Sequence Analysis, DNA , Sequence HomologyABSTRACT
Sex hormones undergo decreases in aging men. Several studies have shown the association of low levels of bioavailable estradiol with osteoporosis in man. To allow a better approach of sex hormones influences, we evaluated bioavailable estradiol concentrations in men and its correlation with age and testosterone. We show that bioavailable estradiol decreases significantly with age. We provide reference values in men with normal testosterone levels.